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Experimental study of antitumor effect of Sanlengqijia Heji

Hu Zongtao,Dong Liuyi,Gao Shan,et al(Dept of Pharmacology,Anhui Medical University,Hefei 230032,China)  
Objective To investigate the anticancer effect of Sanlengqijia Heji in vivo and in vitro.Methods Mice bearing transplanted tumor S180 and Heps were used to study the anticancer effects of Sanlengqijia Heji; MTT assay was used to assess the viability of SMMC-7721 cells treated with different concentrations of Sanlengqijia Heji; strengthening body resistance test was employed to observe the immune function of Sanlengqijia Heji on mice.Results Sanlengqijia Heji obviously inhibited the growth of transplanted tumor S180 and Heps in vivo and significantly inhibited the viability of SMMC-7721 cells in vitro in a dose-dependent manner,strengthening body resistance test suggested that Sanlengqijia Heji could improve the immune function of mice.Conclusion Sanlengqijia Heji has definite anticancer effects in vivo and in vitro on mice and its mechanism may be correlated with inhibiting tumor cell growth and improving immune function of mice.
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