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《Chinese Journal of Medical Computed Imaging》 2001-05
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Differentiation of Benign from Malignant Breast Tumor by Dynamic Enhanced MRI

Tang Weijun,Li Ke,Shen Tianzhen,et alDepartment of Radiology,Huashan Hospital,Fudan University,Shanghai 200040  
Purpose:To evaluate the value of dynamic enhanced MRI in distinguishing benign and malignant breast tumors.Materials and Method:2DFSPGR was used to scan 45 patients with histologically proved benign (14) and malignant (38) breast tumors on a GE 1.5T scanner using a breast phase-array coil.The scan was begun right after the Gd-DTPA administration,and was continuously scanning till 8~10min after the injection.The value of dynamic enhanced MRI was evaluated by calculating the sensitivity and specificity,for which the criteria of morphology,enhancement curve type and enhancement parameters were used.Results:By using the criteria of morphology,the specificity was the highest(93%),and by enhancement curve type,the sensitivity was the highest(100%),on combining these two,the sensitivity and specificity all reached the highest,the diagnostic accuracy was 98%.For the quantitative indexes such as the steepest sloop and enhancement ratio(1min,2min),when the criteria of 3%/s,70%,90% were used,the sensitivity and specificity all reached maximum,being 89%,79%; 95%,64% and 82%,79% respectively.Conclusion:In differentiating benign from malignant breast tumor by dynamic enhanced MRI,higher diagnostic accuracy will be reached when morphology and enhancement curve type criteria are combined.
【CateGory Index】: R737.9
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