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《Chinese Journal of Medical Computed Imaging》 2001-06
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Transthoracic Needle Biopsy under CT Guidance(a Report of 320 Cases)

Li Chengzhou,Liu Shiyuan,Xiao Xiangsheng,et alDepartment of Radiology,Changzheng Hospital,The Second Military Medical University,Shanghai 200003  
To evaluate the diagnostic value and complications of transthoracic needle biopsy of thoracic masses and nodules under CT guidance.Materials and Method:320 patients who underwent transthoracic needle biopsy under CT guidance were collected.267 cases presented with pulmonary lesions,and 30 with mediastinal masses,other 23 cases with pleural and chest wall lesions.Both histopathologic and cytopathologic analyses were involved in all patients.Positive predictive value,sensitivity,specificity,accuracy rate,false-negative rate and pneumothorax occur rate were analysesed.Results:Biopsies in 191 cases yielded malignant lesions,carcinoma cells were not found,in 129 cases which specific-negative results were found in 58 cases,non-specific results in 46,and the renaining 25 cases were found to have false-negative results as the cases were leter proved to be cancer,by operation and follow-up.Positive predictive rate was 100%,sensitivity and specificity were 88.4% and 80.6%respectively,with total accuracy of 92.2%.No false-positive result was found,false-negative rate was 19.4%.Pneumothorax occured in 29(9.1%) of 320 cases,but chest tube placement and drainage were necessary in only five cases(1.6%).Conclusion:CT-guided transthoracic biopsy was a safe and valuable diagnostic method with high sensitivity,to decrease false-negative rate is a key to further improvement.
【CateGory Index】: R816.4
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【References】
Chinese Journal Full-text Database 1 Hits
1 CHEN Xiang-meng a,LIU Xiu-guo a,LIANG Ming-zhu a,WANG Guo-jie a,ZHANG Li-jing a,QIN Pei-xin a,CHEN Kai a,HE Yan-li a,DING Xiang-lian a,YI Xian-ping b a).Department of Radiology;b).Department of Pathology,The 5th Affiliated Hospital of Sun Yat-sen University,Zhuhai 519000,China;CT-guided Biopsy of Thoracic Lesions Using 20-gauge Cutting Needle[J];CT理论与应用研究;2010-04
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 QU Peng,YU Xiao-ling Department of Interventional Ultrasonography,General Hospital of PLA,Beijing 100853,China;Research on Significance and Complications of Ultrasound-guided Percutaneous Biopsy in Diagnosis of Pleura Lesions[J];中国医疗设备;2013-05
2 CAO Dong-xing,CHENG Tao(Department of Medical Imaging,Anhui Provincial Hospital Affiliated to Anhui Medical University Hefei 230001,China);The technique of MSCT-guided percutaneous needle aspiration biopsy of lung[J];中国临床保健杂志;2011-06
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