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《Chinese and Foreign Medical Research》 2011-17
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Matrine injection and intraperitoneal injection of cisplatin efficacy in treatment of cancer ascites

CHEN Cong-zheng1,CHEN Yan-hua2.1Wanbei Coal Mining Group's General Hospital,Suzhou 235123,China  
Objective Matrine injection(Yanshu) intraperitoneal injection of cisplatin treatment of malignant ascites in patients with clinical efficacy.Methods 57 patients with malignant ascites were randomly divided into matrine and cisplatin group(treatment group)31 cases,cisplatin alone(control group)26 cases,two groups of patients in each intraperitoneal injection of the drugs as possible before release make ascites,the treatment group of matrine 30 ml add warm saline injection 200 ml,cisplatin 40 mg add warm saline 200 ml,intraperitoneal injection;the control group of cisplatin 60 mg add warm saline 500 ml,intraperitoneal injection.1 week,4 times for a course of treatment,observation of life in patients with ascites change and quality improvement of conditions.Results There were ascites had disappeared or significantly reduced quality of life in varying degrees of change,but the treatment group was better than the control group.Conclusion Matrine injection and intraperitoneal injection of cisplatin can improve treatment of malignant ascites efficiency,and can improve quality of life,decreased side effects of chemotherapy drugs.
【CateGory Index】: R730.5
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