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《China Medical Devices》 2018-S1
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Therapeutic Effect Observing of Different Medication of Primary Hypertension based on Dynamic Blood Pressure Monitor

JI Fang;Nanjing Occupational Disease Prevention and Control of Hospital;  
Objective To compare and analyze the effect of nifedipine sustained release tablets and nifedipine controlled release tablets in the treatment of primary hypertension. Methods A total of 287 patients with primary hypertension from December 2016 to December 2017 in our hospital were selected, which were divided into two groups, group a and b, with 160 patients in group a and 127 patients in group b. Group a patients were treated with nifedipine sustained-release agent, 20 mg each time, twice a day. Patients in group b were treated with nifedipine controlled release agent, 30 mg each time, once a day, and their dynamic blood pressure was tested 7 weeks later. The blood pressure of group a and group b before and after treatment and the average blood pressure of 24 hours were analyzed. Results Before drug treatment, there was no significant difference in blood pressure between group a and group b(P0.05). After treatment, the difference between group a and group b was statistically significant(P0.05) while comparation was performed in patients with diastolic blood pressure, systolic blood pressure and the mean diastolic pressure within 24 h. The situation of the two groups of patients before and after treatment was statistically significant(P0.01). There was no significant difference between two groups of adverse reaction(P0.05). Conclusion Both nifedipine sustained release tablets and nifedipine controlled release tablets have the function of lowering blood pressure in the treatment of hypertension, but nifedipine controlled release tablets have higher therapeutic performance.
【CateGory Index】: R544.11
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