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《Chinese Journal of Clinical Pharmacology and Therapeutics》 2005-09
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Discussion on basic request and standardization in safety pharmacology

SHI Hong~1, LU Yan-ping~2, QIAN Bo-chu~ 1,2~1 Institute of Materia Medica, Zhejiang Academy of Medical Science, Hangzhou 310013,Zhejiang; ~2 Institute of Materia Medica, Zhejiang University City College, Hangzhou 310015, Zhejiang  
Safety pharmacology is an integrated discipline that has evolved from the distinct fields of pharmacology, physiology and toxicology. Safety pharmacology studies identify, monitor and characterize potentially undesirable pharmacodynamic activities in non-or pre-clinical studies. In this paper the actuality of safety pharmacology is analyzed, the basic request of experiment design is discussed, and the standardization of design for the experiment of central nervous system, cardiovascullar system and respiratory system is discussed.
【CateGory Index】: R96
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