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《Journal of Diffcult and Complicated Cases》 2003-02
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The therapeutic effect of naloxone on treating acute cerebral infarction of large area

HAN Shuanren. Department of Neurology, Taiyuan Central Hospital, Shanxi, Taiyuan 030009,China  
Objective To investigate the clinical effect and safety of naloxone in treating patients with acute cerebral infarction of large area. Methods 91 patients with acute cerebral infarction of large area were randomly divided into two groups, treatment group (n=61) and control group (n=30). All the patients were treated with 20% mannitol in early stage, while the patients in treatment group were given naloxone in addition,2.4 mg once, twice a day, for 14 days. Results The recovery degree of nervous function in treatment group was much better than that of control group (P0.001). The effective rate and total effective rate in treatment group was 36.07% and 86.89 % respectively, compared with those of control group, there was a significant difference between two groups (P0.001). Conclusion Naloxone is an effective and safe drug for treating patients with acute cerebral infarction of large area.
【CateGory Index】: R743.33
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【References】
Chinese Journal Full-text Database 1 Hits
1 YANG Yong-sen,TAO Xia,ZHONG Ze-qing,et al.Center of Difficult and Complicated Disease,Affiliated Taihe Hospital of Yunyang Medical College,Hubei,Shiyan 442000,China;Relationship between the dosage and efficiency of naloxone in the treatment of acute cerebral infarction[J];Chinese Journal of Difficult and Complicated Cases;2006-06
【Citations】
Chinese Journal Full-text Database 1 Hits
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