Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Difficult and Complicated Cases》 2014-03
Add to Favorite Get Latest Update

Clinical features of cerebral gliomas:analysis of 10 cases

ZHANG Lvming;HAN Guoqing;YANG Xu;XU Yicheng;LI Jilai;DU Jichen;Department of Neurology,Beijing Aerospace Center Hospital/Aerospace Clinical Medical College,Peking University;  
Objective To investigate the clinical features,radiological and pathological features of gliomatosis cerebri,in order to improve the diagnosis and treatment.Methods From July 2007 to October 2013,a retrospective analysis of the clinical data of admitted pathological diagnosed brain glioma patients(10 eases) was performed.Results In the 10 patients,there were 6 males and 4 females,aged from 28 to 75 years old,median 47.4 years of age,combined with increased intracranial pressure,neurological deficits or irritating symptoms onset,skull imaging examination showed diffuse lesions,involving ≥3 cerebral lobes.Cranial CT scan showed low density,head MR scan showed slightly lower signal on T1W1,T2W1and FLAIR showed high signal,enhancement scan showed no enhancement or only mild enhancement.All 10 patients were pathologically confirmed,five cases in line with WHO Ⅱ- grade Ⅲ,4 patients in grade Ⅱ,1 case of grade Ⅲ.Pathological examination showed abnormal proliferation of glial cells with mild nuclear shaped,seven cases with diffuse astrocyte-based,two cases with diffuse mainly oligodendrocytes,one case was astrocytes hyperplasia concomitant oligodendrocyte proliferation,revealed "structural growth".Immunohistochemical staining showed GFAP(+ or + +),in some cases Olig-2(- or +) P53showed between 5%- 75%(+) except the main types are oligodendrocyte proliferation,Ki 67 in 5%to 50%(+).Six cases underwent surgery,one case was lost of follow up,rest five cases were survived at the end of follow up;in the 4 cases of non-surgical patients,2 patients died,survived of two cases.Conclusion Gliomatosis cerebri has low incidence.The clinical manifestations are not specific,imaging and pathological examination showed characteristic changes,combined with imaging and pathological findings can improve the accuracy of diagnosis,operation excision of the lesion may prolong the survival time than non-operation treatment.
【CateGory Index】: R739.4
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 3 Hits
1 Yi-dong Chen1,Xiao-guang Qiu2 1.Department of Radiotherapy,Beijing Shijitan Hospital,Capital Medical University,Beijing 100038,P.R.China;2.Beijing Tiantan Hospital,Capital Medical University, Beijing 100050,P.R.China;The Current Management for Gliomatosis Cerebri[J];Chinese Journal of Neuro-Oncology;2012-01
2 LIU Liang GE Wei▲ LUO Shunxiang TANG Tian DING Wanjun The Second Department of Oncology,the People's Hospital of Wuhan University,Hubei Province,Wuhan 430060,China;Clinical curative effect analysis of 109 cases of patients with brain malignant gliomas treated with operation combined with postoperative radiotherapy[J];China Medical Herald;2012-30
3 HUANG Renhua1 SHEN Jialin2 LU Qing2 YAN Junrong2 XIE Huaying1 BAI Yongrui1 1.Department of Chemotherapy,Renji Hospital Affiliated to Medical College of Shanghai Jiaotong University,Shanghai 200127,China;2.Department of Radiology,Renji Hospital Affiliated to Medical College of Shanghai Jiaotong University,Shanghai 200127,China;Application of DWI in the differential diagnosis of brain glioma and brain metastases[J];China Medical Herald;2012-33
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Kun-Wei Liu1,2*,Bo Hu1,3 and Shi-Yuan Cheng1,2 1University of Pittsburgh Cancer Institute,2Department of Pathology,and 3Department of Medicine,University of Pittsburgh School of Medicine,Pittsburgh,PA 15213,USA.;Platelet-derived growth factor receptor alpha in glioma:a bad seed[J];Chinese Journal of Cancer;2011-09
2 XIE Yun-peng,TIAN tian,SHEN Xing-bin,et al(Chengde Medical College,Hebei Chengde 067000,China);EXPRESSION AND SIGNIFICANCE OF TGF-Β1,SMAD7 AND VEGF IN ASTROCYTOMA[J];Journal of Chengde Medical College;2011-01
3 QIAN Yin-feng,YIN Min-min,YU Yong-qiang* Department of Radiology,the First Affiliated Hospital of Anhui Medical University,Hefei 230022,China;Diffusion weighted MR imaging in differentiation of low grade gliomas[J];Chinese Journal of Magnetic Resonance Imaging;2010-01
4 LIU Xin-xin,HAN Xiao-yu,LI Zhi-yong,MIAO Yan-wei Department of Radiology,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China;Immature teratoma of lateral ventricle:one case of MR report[J];Chinese Journal of Magnetic Resonance Imaging;2010-06
5 WANG Fei-fei,CHENG Jing-liang,ZHAO Yi-lei,ZHANG Yong,YAN Chen-yu,BAI Jie,ZHANG Hui-xia,CUI Xiao-lin MRI Room of Radiology Department,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;Dynamic susceptibility contrast perfusion weighted MR imaging in grading of meningioma[J];Chinese Journal of Magnetic Resonance Imaging;2011-01
6 SONG Qian,QI Yue-tong,LI Ying Department of Radiology,General Hospital,Tianjin Medical University,Tianjin 300052,China;Chordoid glioma of the third ventricle:one case report[J];Chinese Journal of Magnetic Resonance Imaging;2011-02
7 LIU Cai-bao, KANG Hou-yi, ZHOU Peng-cheng, XIAO Hua-liang, ZHANG Wei-guo* Department of Radiology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China;One case report of intraspinal diffuse melanocytosis[J];Chinese Journal of Magnetic Resonance Imaging;2011-06
8 ZHAO Jun,ZHOU Jun-lin*,ZHANG Jing Center of Imaging Diagnosis,Second Hospital of Lanzhou University,Gansu Lanzhou 730030,China;MRI diagnosis of different levels of oligodendrogliomas[J];Chinese Journal of Magnetic Resonance Imaging;2012-01
9 Xingli Zhao Yu Tian Zhaohui Li Chao Du Department of Neurosurgery,China-Japan Union Hospital,Jilin University,Changchun 130031,Jilin Province,China. Wei Ji First Ward of Medical Department,Jilin Cancer Hospital,Changchun 130021,Jilin Province.China.;Gliomatosis Cerebri[J];中国肿瘤临床(英文版);2008-04
10 Yin-sheng Chen1,2, Ming-wei Wu1, Fu-rong Chen1, Yun-jie Wang2, Zhong-ping Chen1 1. Department of Neurosurgery/Neuro-oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P. R. China; 2. Department of Neurosurgery, the First Affiliated Hospital, China Medical University, Liaoning Shenyang, 110001, P. R. China;Vasculogenic Mimicry Assay of Glioma Stem Cell in Vitro[J];Chinese Journal of Neuro-Oncology;2010-03
China Proceedings of conference Full-text Database 3 Hits
1 Yuya Yoshida1,Mitsutoshi Nakada1,Naotoshi Sugimoto2,Tomoya Harada1,Yasuhiko Hayashi1,Daisuke Kita1,Naoyuki Uchiyama1,Yutaka Hayashi1,Akihiro Yachie3,Yoh Takuwa2 and Jun-ichiro Hamada1 1 Department of Neurosurgery,Graduate School of Medical Science,Kanazawa University,Kanazawa,Japan 2 Department of Physiology,Graduate School of Medical Science,Kanazawa University,Kanazawa,Japan 3 Department of Pediatrics,Graduate School of Medical Science,Kanazawa University,Kanazawa,Japan;Sphingosine-1-phosphate receptor type 1 regulates glioma cell proliferation and correlates with patient survival[A];[C];2011
2 Department of Neurosurgery, The First Affiliated Hospital, China Medical University, Shenyang, Liaoning Province 110001, People’s Republic of China (Yin-Sheng Chen*, Zhi-Tao Jing, and Yun-Jie Wang) State Key Laboratory for Cancer Research in Southern China and Department of Neurosurgery/Neuro-oncology, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong Province 510060, People’s Republic of China (Yin-Sheng Chen*, Cong Li and Zhong-Ping Chen);Histologic research of microcirculation patterns in human and xengraft model glioblastoma[A];[C];2011
3 Yuya Yoshida Mitsutoshi Nakada Tomoya Harada Shingo Tanaka Takuya Furuta Yasuhiko Hayashi Daisuke Kita Naoyuki Uchiyama Yutaka Hayashi Jun-ichiro Hamada Department of Neurosurgery,Graduate School of Medical Science,Kanazawa University,13-1 Takara-machi,Kanazawa 920-8641,Japan;The expression level of sphingosine-1-phosphate receptor type 1 is related to MIB-1 labeling index and predicts survival of glioblastoma patients[A];[C];2011
【Secondary Citations】
Chinese Journal Full-text Database 4 Hits
1 Song Dayong,Wei Dun,Liao Cunming(Department of Neurosurgery,Affiliated Hospital of North China Coal Uninversity,Jilin 132011,China);Study on effect of psychological intervention on gliomas before and after microsurgery[J];Chongqing Medicine;2011-25
2 CHEN Xin,ZHANG Yong-li,TANG Zhen,LING Yi-tai,ZHOU Dong-jing,DIAO Huan-sheng(Department of Radiology,Chinese Traditional Medical Hospital of Guangdong Province,Guangzhou 510120,China);Differentiation between Solitary Metastases and High-grade Gliomas by using Diffusion,Perfusion and Proton Spectroscopic MR Imaging[J];Journal of Practical Radiology;2008-11
3 LIN Zhi-xiong,TAN Shu-lian,ZHOU Ai-ping,MEI Wen-zhong,HE Li-sheng,JIANG Chang-zhen,KANG De-zhi. Department of Neurosurgery,the First Affiliated Hospital of Fujian Medical University,Fuzhou 350004,Fujian,China;The impact of non-pathological factors on TMZ treatment of cerebral glioma[J];Chinese Journal of Contemporary Neurology and Neurosurgery;2008-05
4 HONG Jian,ZHANG Jian-ning.The Department of Neurosurgery of Huanhu Hospital,Tianjin 300060,China;The Cost-Effectiveness Analysis of Treatment of Neuroglioma by Using the Microneurosurgery Technology[J];Medicine & Philosophy(Clinical Decision Making Forum Edition);2009-04
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved