Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Difficult and Complicated Cases》 2016-11
Add to Favorite Get Latest Update

Clinical effect of BiPAP noninvasive ventilation combined with terbutaline and ambroxol in severe COPD patients

Jiaerken·lasibai;LAN Qiuyan;LI Junmei;Department of Respiratory Medicine,the 474 Hospital of PLA;  
Objective To observe the clinical effect of severe chronic obstructive pulmonary disease(COPD) patients treated by BiPAP noninvasive ventilation combined with terbulaline and ambroxol.Methods From June 2014 to 2015 October,100 patients of severe COPD from PLA 474 hospital were enrolled as object of observation.They divided into noninvasive ventilation group(45 case) and Combined treatment group(55 case),noninvasive ventilation group treated by BiPAP noninvasive ventilation,Combined treatment group treated by BiPAP noninvasive ventilation combined with terbutaline and ambroxol.Clinical effect by Pulmonary function,blood gas indexes and serum inflammatory cytokines levels before and after treatment,adverse reaction conditions were observed.Results The total effective rate in observation group was significantly higher than the control group(98.2%vs.84.4%,χ~2=6.346,P=0.012);the indexes of lung function before treatment in2 groups of 6 minute walk test(6MWT),forced vital capacity(FVC),forced expiratory volume in one second(FEV_1),FEV_1/FVC,maximal mid-expiratory flow(MMEF) and the peak expiratory How rate(PEF) had no statistical significance of PaO_2,pH and blood gas index and PaCO,level difference(P0.05).Alter treatnienl,the 2 groups of patients with lung function index and PaO_2 and pH were higher than that before treatment,PaCO_2 was lower than before treatment,and the observation group changed more obviously than that in control group(P0.05);before treatment,no significant difference between the 2 groups of patients with IL-8,1L-17,hs-CRP,TNF-α index(P 0.05).After treatment,the indexes of the 2groups of patients were lower than that before treatment,and the observation group decreased more obvious than the control group(P0.05).No adverse reactions occurred in 2 groups of patients.Conclusion BiPAP noninvasive ventilation combined with terbutaline and ambroxol has better therapeutic effect in the treatment of severe COPD patients,can significantly improve the patients lung function and blood gas levels.
【Fund】: 新疆维吾尔族自治区科技支疆(指令性)项目(201491121)
【CateGory Index】: R563.9
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 1 Hits
1 Chen Jie;Department of Medicine,Huangshi Central Hospital of Edong Healthcare Group(Affiliated Hospital of Hubei Polytechnic University);;Effect of nasal non-invasive synchronized intermittent mandatory ventilation on acute exacerbation of chronic obstructive pulmonary disease with respiratory failure[J];中国医药;2017-07
Chinese Journal Full-text Database 7 Hits
1 WANG Daofeng;Fu Jun;HE Shigui;WEN Yin;Department of Internal Medicine,Taixing People's Hospital;;Analysis on effect of Chuankezhi injection combined with salmeterol fluticasone on immune function in chronic obstructive pulmonary disease with acute aggravating period[J];疑难病杂志;2015-09
2 HU Zhenyu;ZOU Wailong;Department of Respiration,Beijing Space Center Hospital;;Effects of the changes in serum IL-8,TNF-αand CRP levels of patients with chronic obstructive pulmonary disease in treatment with alprostadil[J];疑难病杂志;2015-06
3 ZHAO Xiao-fang;LI Jian-di;LUO Bo;Zhuji People's Hospital;;Clinical efficacy of montelukast sodium combined with terbutaline in treatment of children with cough variant asthma[J];中华医院感染学杂志;2014-22
4 ;Phenotypes and treatment of chronic obstructive pulmonary disease[J];中华肺部疾病杂志(电子版);2014-02
5 Gao Jingzhen;Chen Baoyuan;Department of Respiratory Medicine,Tianjin Medical University,Tianjin 4th Center Hospital;;The curative effect of sustaining treatment by ambroxol in different hours for patients with acute exacerbation of chronic obstructive pulmonary disease[J];中华老年医学杂志;2014-03
6 ZHANG Jing;YUE Hong-mei;Department of Respiratory ,the First Hospital of Lanzhou University;Department of Respiratory,the Jinchuan Group Hospital;;Clinical observation of BiPAP combined with compressing inhalation of terbutaline plus ambroxol of treating COPD patients[J];甘肃医药;2014-02
7 XU Hai-song;HU Yan-xia;JIANG Qi-zhou;Hangzhou Normal University Affiliated Hospital;;Clinical significance of ambroxol hydrochloride in treatment of postoperative pulmonary infections in hypertensive intracerebral hemorrhage patients[J];中华医院感染学杂志;2014-01
Chinese Journal Full-text Database 9 Hits
1 Liu Xin;Zhang Junxia;Department of Medicine,Shangqiu First People's Hospital;;The clinical efficacy of Huatan and Boosting Qi therapy combined with moxifloxacin in the treatment of patients with acute exacerbation of chronic obstructive pulmonary disease and its effect on cytokine and hemorheology[J];国际医药卫生导报;2016-23
2 AN Xiaojie;NIE Qingrong;DENG Ganfei;Liangxiang Teaching Hospital Affiliated to Capital Medical University;;Influence of Moxifloxacin Combined Gung Piperacillin Sodium / Tazobactam on Immunoglobulin PCT and CRP of Patients with COPD Combined Acute Lower Respiratory Tract Infection[J];河北医学;2015-12
3 CHEN Jin-long;ZHUANG Si-si;QIN Yu-ming;CAO LI-ming;YANG Shi-wei;CHENG Xue-ying;Nanjing Children's Hospital,Nanjing Medical University;;Clinical observation of macrolides in the treatment of children with cough variant asthma caused by Mycoplasma pneumoniae infections[J];中华医院感染学杂志;2015-23
4 XIONG Hanzhong;WANG Zhi'an;ZHANG Fuyu;Department of Respiration,Ezhou Central Hospital;Department of Endocrinology,Ezhou Central Hospital;;Research of piperacillin sodium/tazobactam combined moxifloxacin in treatment of patients with COPD combined acute lower respiratory tract infections[J];西部医学;2015-11
5 LIANG Xu-man;HUANG Gan;Yangjiang Hospital of Traditional Chinese Medicine;;Curative Effect Observation of Ambroxol Hydrochloride and Symptomatic Treatment in the Treatment of COPD Patients with Pulmonary Infection[J];中国医学创新;2015-32
6 FENG Zhi-hong;NIE Xiu-hong;Department of Respiratory,Xuanwu Hospital Affiliated to Capital Medical University;;Efficacy of Montelukast sodium in the treatment of cough variant asthma and its influence on inflammatory mediators in induced sputum[J];临床肺科杂志;2015-11
7 QIU Yan;ZHOU Xiao-lei;CAO Ying;Department of Respiratory Medicine,the Fifth People's Hospital of Xinyang;;Significance of vital capacity and forced vital capacity in evaluation of degree of airway limited in stable COPD patients[J];医药论坛杂志;2015-09
8 PAN Xue-dong;ZHANG Hong;LIU Mao-hong;Department of Respiratory Medicine,Pixian People's Hospital;;Effect observation of ambroxol sequential treatment for acute exacerbation of chronic obstructive pulmonary disease[J];实用医院临床杂志;2015-05
9 LI Shuping;LIU Xueguan;WEI Qing;TANG Yuyi;XIANG Hui;DENG Tingjun;Department of Respiratory Medicine,Hechi Hospital of Traditional Chinese Medicine;Department of Respiratory Medicine,People’s Hospital of Hechi;;Analysis of clinical efficacy of montelukast combined with seretide for cough variant asthma[J];右江医学;2015-04
Chinese Journal Full-text Database 4 Hits
1 Li Rufang;Department of Respiratory Medicine,the Third People's Hospital of Datong City;;Effect of noninvasive positive pressure ventilation on pulmonary function in patients with chronic obstructive pulmonary disease complicated with chronic respiratory failure[J];中国医药;2016-07
2 Liu Xiaoli;Liu Fangxun;Zhang Hua;Liu Fang;Niu Zhihong;Huang Xiuqing;Jiang Yanwen;Department of Respiratory and Critical Care Medicine,Beijing Shijitan Hospital,Capital Medical University;Department of Community Health Center,Beijing Shijitan Hospital,Capital Medical University;Beijing Institute of Geriatrics,Ministry of Health,Beijing Hospital;;Clinical observation of Bi-level positive airway pressure ventilation therapy treating overlap syndrome[J];中国医药;2016-05
3 Cheng Xi;Shen Ya-wei;The people's liberation army 105 hospital;The Forth Affiliated Hospital of AnHui Medical University;;The comparison of different mechanical ventilation mode in saving acute lung injury[J];中国临床医生;2014-06
4 HOU Jing-yu (Department of Emergency,The First Affiliated Hospital of Xinxiang Medical College,Weihui 453100,Henan Province,China);Effect of two ventilation modes on the peripheral circulation and blood gas analysis in chronic obstructive pulmonary disease complicated with respiratory failure patients[J];中国临床药理学杂志;2013-03
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 LIN Zhen-huai;SUN Yan-cheng;WANG Yong-cang;YANG Yu-liang;WANG Jian;Department of Respiratory Diseases,the Second Central Hospital of Baoding;;Influence and Curative Effect of Salmeterol Xinafoate and Fluticasone Propionate on Inflammatory Factors of AECOPD Patients[J];解放军医药杂志;2015-02
2 LI Lizhen;LI Quanqing;WU Ying;LIU Zhonghua;Department of Nephrology, Hunan Mawangdui Hospital;;Effects of Prostaglandin E1 on the Microinflammatory State of the Elderly Patients with Maintenance Hemodialysis[J];中外医疗;2014-35
3 YUAN Gui-hong;SUN Hang-cheng;WANG Yue;JING Li-jun;Jin Tan City Hospital of traditional Chinese Medicine;;Clinical Observation of Chuankezhi Injection on acute exacerbation of COPD[J];中医药导报;2014-12
4 GUO Shao-mei;YU Jie;Cadre Respiratory Ward,Jiangxi Provincial People's Hospital;;Effect of Lipo Prostaglandin E1 Injection on Pulmonary Arterial Hypertension in Patients with Chronic Obstructive Pulmonary Disease[J];南昌大学学报(医学版);2014-07
5 Cui Zhengsen;Li Han;Jiang Baozhen;Dept of Geriatric Respiratory Diseases,The First Affiliated Hospital of Anhui Medical University,The Institute of Pulmonology,Anhui Medical University;;The elevated level of HMGB1 in serum and its clinical role in patients with COPD,pneumonia and lung cancer[J];安徽医科大学学报;2014-06
6 ZHANG Chunchi;DONG Yanjuan;HE Yue;HE Xin;Third Department of Internal Medicine,Beijing Military Region Hospital;;Effect of alprostadil injection on cerebral blood flow in transient ischemic attack[J];疑难病杂志;2014-05
7 ZHU Qin-rui;ZHOU Zheng-min;Department of Respiratory Medicine,Affiliated Hospital of Weifang Medical University;;Impact of Salmeterol and Fluticasone Propionate Powder on Brain Natriuretic Peptide and High Sensitivity C-reactive Protein of COPD Patients with Respiratory Failure[J];医学综述;2014-06
8 ZHANG Lin;Department of Emergency,Affiliated Hospital of Yan'an University;;Change of Inflammatory Factors and the Effect of Salmeterol Fluticasone Propionate in AECOPD Patients[J];医学综述;2014-03
9 Hu Zhengbo;Chen Lujia;Lu Haibo;Liu Lili;452 Hospital of PLA;;Systematic Evaluation on Chuankezhi Injection for Treating Chronic Obstructive Pulmonary Disease[J];中国药业;2013-23
10 YUAN Li-xin;Shenyang Ninth People's Hospital;;Clinical Efficacy of Salmeterol Xinafoate and Fluticasone Propionate Powder for Inhalation for Patients with Pneumonoconiosis Complicated with Acute Exacerbations of Chronic Obstructive Pulmonary Disease[J];中国医院用药评价与分析;2013-10
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved