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《Journal of Yunnan University of Traditional Chinese Medicine》 2015-05
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The Clinical Effect of Intralesional Glucocorticoid Injection in the Treatment of Alopecia Areata Patients with Eyebrow Loss Symptom

SUN Dan;YANG Xiaohong;HE Huiying;TAO Maocan;LU Xianchang;CAO Yi;The First Affiliated Hospital of Zhejiang Chinese Medical University;  
Objective To observe the clinical effect of local injections with glucocorticoid for alopecia areata(AA) patients who with eyebrow loss. Methods 60 AA patients with eyebrow loss were divided into three groups in order of been diagnosed initially.20 cases in the treatment group were treated with diprospan suspension localized injection biweekly and hair-promoting capsules Ⅰorally taken five capsules per time and three times per day;20 cases in the control groupⅠ were treated with diprospan suspension localized injection biweekly;20 cases in the control group Ⅱ were treated with hair-promoting capsules Ⅰ orally taken five capsules per time and three times per day;The injection of the glucocorticoid suspension was stopped after 8 weeks,while hair-promoting capsuleⅠwas continued to 12 weekends. The observational indicator was evaluated at baseline,2nd weekends,4th weekends,8th weekends and 12 th weekends after treatment. Results The difference of clinical effects showed significance as time goes on(F=218.253,P 0.01);Time factors and group factors had interactive effects on clinical effects:the clinical effect of treatment group and control group showed gradual improvement as time goes on(F=7. 709,P0.01);The clinical effect of treatment groups were more significant than control group(P 0.01),the difference between control group Ⅰ and control group Ⅱ was not obvious(P 0.05).Conclusion The glucocorticoid localized injection has many characteristics with simplicity operation,quickly and precisely clinic effect,and its side effect would gradually resolved as time goes on after glucocorticoid withdrawl. Combination of glucocorticoid localized injection and hair-promoting capsulesⅠorally taken is worth to promote to treat AA patients with eyebrow loss symptom.
【Fund】: 全国名老中医专家传承工作室建设项目—鲁贤昌名中医工作室(国中医药人教涵[2012]149号)
【CateGory Index】: R758.71
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 LI Xin,YANG Rui,ZANG Qiang,HU Yong-xiu(School of Basic Medical Sciences,Capital University of Medical Sciences,Beijing 100069,China);Pharmacological actions of glucocorticoids:progress in mechanisms[J];Journal of International Pharmaceutical Research;2009-01
2 LOU Wei-hai,CHEN Wei-wen(Beijing TCM Hospital Affiliated to Capital Medical University,Beijing 100010,China);Clinical features and syndrome differentiation of alopecia areata on 411 cases[J];China Journal of Traditional Chinese Medicine and Pharmacy;2011-09
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Lu'an People's Hospital , Lu'an 237005,Anhui LI Lin;Female facial recurrent dermatitis to the clinical analysis of 58 cases[J];Journal of Anhui Health Vocational & Technical College;2008-04
2 Liu Xuegong,Cheng Yizhuang,Hong Bo,et alDeptment of Nuclear Medicine,The Affiliatted Provincial Hospital of Anhui Medical University,Hefei 230001;Strontium-90 beta plesiotherapy treated capillary haemangioma in enfant skin[J];Anhui Medical Journal;2009-07
3 YAN Huai-shi,BAI Ya-ping(Department of Acupuncture and Moxibustion,Anhui Provincial Hospital,Anhui Hefei 230001,China);Acupoint Injection in Treatment of Hiccups after Abdominal Operation:A Report of 41 Cases[J];Journal of Anhui Traditional Chinese Medical College;2010-06
4 Li Weihong,Huang Shao,Tan Xiaoyan,et al Xinfu Branch of Maoming City People Hospital,Guangdong Province(525000);Therapeutic Effect Observation of Psoriasis Treated with Chinese Drug Hilum Application and Preservation Enema[J];Journal of Zhejiang University of Traditional Chinese Medicine;2008-04
5 TIAN Li-ming,HU Yao-hua(Department of Dermatology,South China Hospital,South China University,Hengyang 421002);Study on correlation between CAG polymorphisms of androgen receptor gene and the acne cystica of Han population in Hunan Province[J];Beijing Medical Journal;2009-02
6 XU Pei-hong1,YUAN Ding-fen1,XUE Feng2,et al.(1.Department of Dermatology,Shanghai The Sixth People′s Hospital,Shanghai Jiao Tong University,Shanghai 200233,China;2.Department of Dermatology,Ruijin Hospital,Medical School,Shanghai Jiao Tong University,Shanghai 200025,China);Study on the expressions of TLR 2,3,9 mRNA in the peripheral blood mononuclear cells of Condylomata acuminata[J];Chongqing Medicine;2010-15
7 CHENG Juan,DUAN Hong-yan,LI An-xin Dermatology and STD Center,Out-Patient Clinic,302 Hospital of PLA,Beijing 100039,China;Current state of epidemiology,diagnosis and treatment of syphilis[J];Infectious Disease Information;2012-01
8 TANG Jian-Ping,YANG Yu-Jia,SUN Lei.Department of Dermatology,Hunan Children′s Hospital,Changsha 410007,China;Expression of blood Toll-like receptors and cytokines in children with recurrent herpes simplex[J];Chinese Journal of Contemporary Pediatrics;2009-09
9 ;复方氟米松软膏治疗湿疹皮炎类皮肤病临床疗效观察[J];Contemporary Medicine;2012-02
10 ;派瑞松联合盐酸布替萘芬擦剂治疗头部脂溢性皮炎疗效观察[J];Contemporary Medicine;2012-10
China Proceedings of conference Full-text Database 3 Hits
1 ;除湿饮治疗老年湿热内蕴型亚急性湿疹的临床研究[A];[C];2008
2 XU Jia ZHANG Cang WANG Ping (Beijing Traditional Chinese Medicine Hospital of Capital Medical University,Beijing 100010,China);Clinical Observation and Animal Studies on Effect of Compound Qin-Bai ointment in Treating Active stage Psoriasis[A];[C];2008
3 LIU Ying(Hubei University of traditional Chinese Medicine 420079 );Clinical observation of the collagen mask and red light treatment of facial contact dermatitis[A];[C];2012
【Secondary Citations】
Chinese Journal Full-text Database 8 Hits
1 WANG Guo bin,YI Wei,SHE Shi feng (1998 Grade postgraduate,Guangzhou University of Traditional Chinese Medicine,Guangdong Guangzhou 510405,China);ANALGESIC EFFECT OF DIFFERENT DRUG POINT-INJECTION THERAPY IN RATS OF ADJUVANT ARTHRITIS[J];Journal of Anhui Traditional Chinese Medical College;2002-01
2 ;Contrast Observation on Injection Metoclopramide in Different Acupuncture Point for the Treatment of Emesis after Chemical Treatment to Mammary Cancer[J];Hunan Guiding Journal of Traditional Chinese Medicine and Pharmacology;2004-02
3 Yang Renda dt al(Department of Acupuncture and Moxibustion,410007);STUDY ON INTEKRELATION OF CHANNEL POINTS AND ZANGFU ORGANS BASED ON DKUG ACTION OF POINT INJECTION[J];JOURNAL OF HUNAN COLLEGE OF TRADITIONAL CHINESE MEDICINE;1995-04
4 Du Junrong (School of Pharmacy, West China University of Medical Sciences Chengdu 610041);INHIBITION OF PROLIFERATION OF HUMAN SMOOTH MUSCLE CELLS BY TANSHINONEⅡA[J];WEST CHINA JOURNAL OF PHARMACEUTCAL SCIENCES;1999-01
5 HU Xiaomin, YIN Xiaotao, YIN Wen, LI Yuecai. Department of Emergency Medicine,Xijing Hospital ,the Fourth Military Medical University ,Xi'an 710032,China;Effects of Ligustrazini on activation of NF-κB in pulmonary alveolar macrophages(PAM) in rabbits[J];Journal of Emergency Medicine;2005-09
6 ZHANG Xue-jun, LI Hui, YANG Sen, ZHANG An-ping, LIN Da, FAN Li, WANG Pei-guang, WANG Zai-xing (Institute of Dermatology of Anhui Medical University, Hefei 230022, China);An open multi-center clinical trial with compound betamethasone injection for the treatment of light drug eruption[J];Journal of Clinical Dermatology;2008-06
7 Wang Nan;et al.(Atherosclerosis Research Center);Inhibition of Bovine Smooth Muscle Cell-mediated Low Density Lipoprotein Oxidation by Salviae Miltiorrhizae[J];ACTA ACADEMIAE MEDICINAE NANJING;1994-04
8 LI Zhao-liang1,SHI Qiu-ling2,ZHU Ping-xian3(1.Department of Emergency,Nan'ao People's Hospital of Shenzhen, Shenzhen 518121,China;2.Department of Ultrasound,Shenzhen People's Hospital, Shenzhen 518000,China;3.Department of Internal Medicine,Longgang District People's Hospital of Shenzhen,Shenzhen 518172,China);Intervention Effect of Tanshinone ⅡA on Vascular Endothelial Cell Function in Patients with Atherosclerosis[J];Journal of Nanchang University(Medical Science);2012-07
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