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《Chinese Journal of Conservative Dentistry》 2001-01
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The combining effects of recombinant human bone morphogenetic protein-2 and basic fibroblast growth factor on the proliferation of human periodontal ligament cells

WU Yong,WU Zhi-fen,WANG Qin-tao, et al ( College of Stomatology,The Fourth Military Medical University, Xi'an 710032,China )  
AIM: To evaluate the effects of a combination of recombinant human bone morphogenetic protein-2 (rhBMP-2)and basic fibroblast growth factor(bFGF) on the proliferation of periodontal ligament cells(PDLCs). METHODS: Using cell culture technique, enzyme kinetics methods. RESULTS: Both rhBMP-2 and bFGF could promote the proliferation of PDLCs. Significantly greater proliferation was found in combined group comparing with individual groups ( P 0.05) . CONCLUSION: rhBMP-2 and bFGF could promote the proliferation of PDLCs and had synergistic action.
【Fund】: 国家自然科学基金资助课题!(3970 0 0 35 )
【CateGory Index】: R780.2
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