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《Chinese Journal of Pharmaceutical Analysis》 2013-12
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Determination of isoimperatorin and nodakenin in Notopterygium incisum by high performance liquid chromatography- tandem mass spectrometry

SHEN Yan;HAN Chao;HUANG Fu-zhen;ZHU Zhen-ou;LEI Xin-xiang;College of Chemistry and Materials Engineering,Wenzhou University;Wenzhou Entry-Exit Inspection and Quarantine Bureau;  
Objective: To establish a high performance liquid chromatography- tandem mass spectrometry( HPLC- MS / MS) method for the determination of isoimperatorin and nodakenin in Notopterygium incisum. Methods: The sample was extracted by ultraphonic extraction,and diluted in methanol for further analysis. The analysis was performed on a C 18 column( 150 mm × 2. 1 mm,3. 5 μm) using a gradient elution program with the mobile phase of 0. 1% acetic acid solution and acetonitrile. The analyte was determined by an electrospray ionization tandem mass spectrometry in multiple reactions monitoring( MRMs) mode. The qualitative and quantitative analyses were based on the retention times and characteristic ion pairs consisting of one parent ion and two fragment ions of the analyte. Results: The limits of detection( LODs) for isoimperatorin and nodakenin were 0. 03 ng · mL- 1and 0. 015 ng · mL- 1,and the limits of quantification( LOQs) were 0. 10 ng·mL- 1and 0. 05 ng·mL- 1. The average recovery was 93. 6% with RSD of 2. 4% for isoimperatorin,94. 5% with RSD of 2. 6% for nodakenin. Conclusion: This established method is simple,reliable,and sensitive,which is suitable for the analysis of isoimperatorin and nodakenin in Notopterygium incisum.
【Fund】: 国家自然科学基金(30900129)资助
【CateGory Index】: R284
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【References】
Chinese Journal Full-text Database 1 Hits
1 Yu Jiang;Feng Jiafu;Zeng Bangguo;Department of Pharmacy,Leshan Vocational and Technical College;;Effectiveness analysis of determining the content of notopterol and isoimperatorin in notopterygium[J];Chongqing Medicine;2014-35
【Citations】
Chinese Journal Full-text Database 7 Hits
1 JIANG Hai-qiang,ZHANG Ying,RONG Rong**(Shandong University of Traditional Chinese Medicine,Jinan,Shandong 250355,China);GC-MS analysis for volatile compounds in Rhizoma et Radix notopterygii by headspace injection[J];Chinese Journal of Pharmaceutical Analysis;2011-04
2 LI Chun-li1,2,ZHOU Guo-ying1,3,ZHOU Yu-bi1(1.Northwest Institute of Plateau Biology,Chinese Academy of Sciences,Xining 810001,China; 2.Graduate University of Chinese Academy of Sciences,Beijing 100049,China;3.Key Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology,Chinese Academy of Sciences,Xining 810001,China);Determination the contents of six trace elements in different organs of wild Notopterygium incisum Ting ex H.T.Chang and Notopterygium forbesii Boiss by flame atomic absorption spectrometry[J];Chinese Journal of Pharmaceutical Analysis;2011-10
3 YANG Andong,MA Yan,WANG Jia,YANG Jun(Sichuan Institute of Chinese Material Medica,Chengdu610041,China);Content Determination of Isoimperatorin in Cultivated Notopterygium[J];China Pharmacy;2006-15
4 SUN Yu ru, LI Xian duan, SUN You fu (Institute of Chinese Materia Medica,China Academy of Traditional Chinese Medicine, Beijing 100700);Determination of Content of Nodakenin in Notopterygium incisum Ting from Different Source by HPLC[J];China Journal of Chinese Materia Medica;2001-11
5 ZHOU Yi1,JIANG Shun-yuan1,SUN Hui2,YANG An-dong1,MA Yan1,MA Xiao-jun3,WU Rui4(1.Sichuan Institute of Chinese Materia Medica,Chengdu 610041,China;2.Sichuan University,Chengdu 610065,China;3.Institute of Medicinal Plant,Beijing Union Medical College & Chinese Academy of Medical Sciences,Beijing 100094,China;4.Sichuan Provincial Drug Administration,Chengdu 610015,China);Quantitative analysis of volatile oils and isoimperatorin in Rhizoma et Radix Notopterygii[J];China Journal of Chinese Materia Medica;2007-07
6 LIU Wei-gen1,3,WANG Liang-sheng2,XU Wen-hua1,YANG Lu-cun1,ZHU Man-lan4, ZHOU Guo-ying1(1.Key Laboratory of Adaptation and Evolution of Plateau Biota,Northwest Institute of Plateau Biology,Chinese Academy of Sciences,Xining 810008,China;2.Beijing Botanical Garden,Institute of Botany,Chinese Academy of Sciences,Beijing 100093,China;3.Graduate University of Chinese Academy of Sciences,Beijing 100049,China;4.Nanjing Agriculture University,Nanjing 210095,China);Quantitative analysis of organic acids and coumarins in Notopterygium incisum of different specifications[J];Chinese Traditional Patent Medicine;2012-11
7 LIU Wei-gen1,3,WANG Liang-sheng2,ZHOU Guo-ying1,XU Wen-hua1, YANG Lu-cun1,ZHU Man-lan4(1.Key Laboratory of Adaptation and Evolution of Plateau Biota,Northwest Institute of Plateau Biology,Chinese Academy of Sciences, Xining 810008,China;2.Beijing Botanical Garden,Institute of Botany,Chinese Academy of Sciences,Beijing 100093,China; 3.Graduate University of Chinese Academy of Sciences,Beijing 100049,China;4.Nanjing Agriculture University,Nanjing,210095);Comparison of the contents of organic acids and coumarin compounds in different parts of Notopterygium incisum[J];Chinese Journal of Pharmaceutical Analysis;2012-11
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LI Chun-li1,2,ZHOU Yu-bi1,ZHOU Guo-ying*1,3,SUN Jing1,3,YANG Lu-cun1,2 and XU Wen-hua1,3(1.Northwest Institute of Plateau Biology,Chinese Academy of Sciences,Xining 810001;2.Graduate University of Chinese Academy of Sciences,Beijing 100049;3.Key Laboratory of Adaptation and Evolution of Plateau Biota,Northwest Institute of Plateau Biology,Chinese Academy of Sciences,Xining 810001);Comparison analysis of contents and constituents of volatile oils extracted from wild and cultivated rhizoma et radix notopterygii[J];Chinese Journal of Analysis Laboratory;2012-01
2 LI Chun-li1,2,ZHOU Guo-ying1,3,HU Feng-zu1,XU Wen-hua1,3,CHEN Gui-chen1,31.Northwest Institute of Plateau Biology,Chinese Academy of Sciences,Xining810001,China2.Graduate University of Chinese Academy of Sciences,Beijing100049,China3.Key Laboratory of Adaptation and Evolution of Plateau Biota,Northwest Institute of Plateau Biology,Chinese Academy of Sciences,Xining810001,China;Determination of Trace Determination of Elements in Medicinal Materials of Cultivated and Wild Rhizoma et Radix Notopterygii Vegetated in Different Months by Flame Atomic Absorption Spectrometry[J];Spectroscopy and Spectral Analysis;2011-04
3 ZHU Zhen-yu,CAI Ya-mei and CHAI Yi-feng(School of Pharmacy,Second Military Medical University,Shanghai 200433);Pharmaceutical Analysis(Chinese Journals)[J];Chinese Journal of Analysis Laboratory;2012-10
4 LI Lihua(Chemical and Environmental Sciences,Shaanxi University of Technology,Shaanxi Hanzhong 723000,China);Determination of Six Trace Metal Elements in Pleurotus eryngii Quel. by Microwave Digestion-AAS[J];Guangdong Trace Elements Science;2013-02
5 ZHANG Guoyue;ZHANG Yuehua;ZHAO Li;Shanxi Insititute for Food and Drug Control;Xi'an Institute for Food and Drug Control;The Second Affiliated Hospital of Xi'an Jiao Tong University;;Quality standard for pediatric cold tablets[J];China Medicine and Pharmacy;2013-21
6 HUANG Xiang;WANG Xiao-ping;Yulin Normal Univresity;;Research on the Content of Mineral Elements in Radix Millettiae Speciosae by Flame Atomic Absorption Spectroscopy Determination[J];Journal of Anhui Agricultural Sciences;2014-21
7 ZHU Mei-xiao1,2,YI Jin-hai2,LIU Yun-hua2,CHEN Yan2 (1. Luzhou Medical College,Luzhou,Sichuan,646000 P. R. China;2. Sichuan Academy of Chinese Medicine Sciences,Chengdu, Sichuan,610041 P. R. China);Determination of total ferulic acid in Rhizoma et Radix Notopterygii by RP-HPLC[J];West China Journal of Pharmaceutical Sciences;2010-02
8 HUANG Yu-sheng1,YUAN Xian-lin2,ZHONG Yu,WANG Ru-jun1;Determination of the contents of nodakenin in Notopterygii Rhizoma et Radix by HPLC[J];Chinese Journal of Ethnomedicine and Ethnopharmacy;2013-10
9 Xiang HUANG;Xiaoping WANG;Xiaobai CHEN;Yulin Normal University;;Determination of the Content of Mineral Elements in Radix Millettiae Speciosae by Flame Atomic Absorption Spectrometry[J];药用植物研究(英文版);2014-07
10 WU Xue;WANGYan;ZHANGYun-li;ZHANG Wei;Study of grade 2012 students in Shandong University of Traditional Chinese Medicine School of Medicine;Qingdao Haici medical group;;Study on supercritical extraction technology of drug in Liangxue Huoxue Capsule[J];Guiding Journal of Traditional Chinese Medicine and Pharmacy;2015-11
【Co-references】
Chinese Journal Full-text Database 9 Hits
1 WANG Pei-xiang1,XING Yue-wen2,LUO Yan3,SUN Yan-xiu1,HUO Gui-lan1,SUN Chang-shan1(1.School of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China;2.Henan Coal Health School,Pingdingshan 467013,China;3.Shenyang Yaoda Pharmaceutical Limited Liability Company,Shenyang 110016,China);Determination of related substances in rifampin,isoniazid and pyrazinamide tablets by HPLC[J];Journal of Shenyang Pharmaceutical University;2013-02
2 WANG Zhen1,2,CHEN Shilin1,HUANG Linfang1*,SONG Jingyuan1,DU Jing1(1.Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing 100193,China;2.School of Chinese Materia Medica,Beijing University of Chinese Medicine,Beijing 100102,China);Advances in Quality Control of Notopterygii Rhizoma et Radix[J];Chinese Journal of Modern Applied Pharmacy;2012-03
3 CHEN Yan1,YI Jin-hai1,LIU Yun-hua1,ZHU Mei-xiao1,2(1.Sichuan Academy of Chinese Medicine Sciences,Chengdu 610041,China;2.Luzhou Medical College,Luzhou 646000,China);Study on the quality standard for Notopterygii Rhizoma et Radix[J];Chinese Journal of Pharmaceutical Analysis;2010-05
4 SHI Wan-zhong,LI Shi-fang,LIU Jin,LIU Li,XU De-sheng(Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200021,China);Content changes of evodiamine and rutaecarpine in Compound Lingtong Capsule in stability testing[J];Chinese Traditional Patent Medicine;2011-08
5 SUN Hui1,JIANG Shunyuan2*,CHEN Shilin3,ZHOU Yi2,XIE Caixiang3,MA Xiaojun3,CHEN Tiezhu2(1.Department of Environmental Science and Engineering,Sichuan University,Chengdu 610065,China;2.Sichuan Academy of Traditional Chinese Medicine Sciences,Chengdu 610041,China;3.Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences,Chinese Peking Union Medical College, Beijing 100094,China);Studies on habitats suitability of endangered medicinal plant Notopterygium incisum[J];China Journal of Chinese Materia Medica;2009-05
6 Peng Lingfang.Xia Weijun,Cui Tao(Yunnan Institute of Materia Medica,Kunming 650111,China);Determination of Total Saponins and Oleanolic Acid in Schefjlera Venulosa Extracts[J];China Pharmacist;2012-11
7 ZHANG Hua1,DONG Li-sha1*,CHEN Hu-biao2*,HE Xi-cheng1,GE Xiang-qian1,ZHANG Xi-gui1,ZHOU Ying-ying1(1.Guiyang College of Traditional Chinese Medicine,Guiyang 550002,China; 2.School of Chinese Medicine,Hong Kong Baptist University,Hong Kong,China);Content detemination of total tannin in Smilax glabra with reddish brown and off-white colored cross section[J];China Journal of Chinese Materia Medica;2013-06
8 GAO Sen;LI Zheng-xiang;WANG Zhi-tao;FANG Zhi-zhong;General Hospital,Tianjin Medical University;Department of Pharmacy,College of Pharmacy,Tianjin Medical University,Tianjin Key Laboratary on Technologies Enabling Development of Clinical Therapeutics and Diagnostics ( Theranostics);;Determination of prim-O-glucosylcimifugin, 4'-O-β-D-glucosyl-5-O-methylvisamminol,notopterol,isoimperatorin and asarinin in Jiulong Huafeng Pills by HPLC[J];Chinese Traditional Patent Medicine;2014-03
9 WANG Dong-mei;WANG Zhen;HUANG Lin-fang;Institute of Medicinal Plant Development,Chinese Academy of Medical Science;;Comparison of Anti-inflammatory Effects and the Contents of 4 Compounds from Cultivated and Wild Notopterygii Rhizoma Et Radix[J];China Pharmacy;2014-03
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Fan Hui;Jin Youju;Li Jiquan;Chen Huajun. School of Biological Sciences and Biotechnology, Beijing For. Univ.,100083, P.R. China.;Advances on plant volatile semiochemicals attracting herbivorous insects[J];Journal of Beijing Forestry University;2004-03
2 WANG Hai-Bo DI Xue BAO Yong-Rui MENG Xian-Sheng CAO Ai-Min(Liaoning University of T.C.M.,Dalian,Liaoning 116600,P.R.China);Chromatography Fingerprint of Rhizoma et Redix Notopterygii by HPLC-Fluorescence Detection[J];Chinese Journal of Spectroscopy Laboratory;2010-02
3 Yanming LIU Department of Chemistry,Henan Xinyang Teacher′s College,464000 Xinyang;Determination of Ten Trace Elements in Chinese Traditional Medicines by Atomic Absorption Spectrometry[J];SPECTROSCOPY AND SPECTRAL ANALYSIS;2000-03
4 CHENG Fa liang 1,NING Man xia 1,MO Jin yuan 2,and LIANG Ye cheng 3 1 Department of Applied Chemistry, Dongguan Institute of Technology,Dongguan 523106,China 2 Department of Chemistry, Zhongshan University,Guangzhou 510275,China 3 Chinese;Determination of Trace Elements in Lychee of Different Growth Periods[J];Spectroscopy and Spectral Analysis;2002-04
5 WANG Xiao-yi, Zhu W, Witkamp G T, ZENG Yan-jun The Analytical and Testing Center, Beijing Polytechnic University, Beijing 100022, China; The Laboratory of Process Equipment, the Technology University of DELFT, DELFT, the Netherlands; The Centers of Bio-Medical Engineering, Beijing Polytechnic University, Beijing 100022, China;Determination of Trace Elements in Huang-Lian by High Resolution-Inductively Coupled Plasma-Mass Spectrum[J];Spectroscopy and Spectral Analysis;2003-06
6 FAN Wen-xiu~1,LI Xin-zheng~21.Department of Chemical Engineering,Henan Institute of Science and Technology,Xinxiang 453003,China2.Department of Horticulture,Henan Institute of Science and Technology,Xinxiang 453003,China;Spectrometric Determination of Trace Elements in Pagoda Flower[J];Spectroscopy and Spectral Analysis;2005-10
7 WANG Wei-ling1,LIANG Zong-suo1,2,TAN Yong2,DUAN Qi-mei11.College of Life Science,Northwest A & F University,Yangling 712100,China2.Institute of Soil and Water Conservation,Chinese Academy of Sciences and Ministry of Water Resource,Yangling 712100,China;Determination of Mineral Elements in Different Part of Astragalus Membranaceus(Fisch.) by FAAS[J];Spectroscopy and Spectral Analysis;2008-05
8 SHENG Ji-ping,CHEN Hai-rong,SHEN Lin College of Food Science and Nutritional Engineering,China Agricultural University,Beijing 100083,China;Determination of Six Mineral Elements in Roots,Stems,Leaves,Flowers and Seeds of Scutellaria Baicalensis by FAAS[J];Spectroscopy and Spectral Analysis;2009-02
9 LI Chun-li1,2,ZHOU Guo-ying1,3,HU Feng-zu1,XU Wen-hua1,3,CHEN Gui-chen1,31.Northwest Institute of Plateau Biology,Chinese Academy of Sciences,Xining810001,China2.Graduate University of Chinese Academy of Sciences,Beijing100049,China3.Key Laboratory of Adaptation and Evolution of Plateau Biota,Northwest Institute of Plateau Biology,Chinese Academy of Sciences,Xining810001,China;Determination of Trace Determination of Elements in Medicinal Materials of Cultivated and Wild Rhizoma et Radix Notopterygii Vegetated in Different Months by Flame Atomic Absorption Spectrometry[J];Spectroscopy and Spectral Analysis;2011-04
10 WANG Ping1,WU Zhao-yun2,WU Shu-hua3,JIN Jin-hua11.Shanghai Dehua Pharmaceutical Company Limited;2.Shanghai Institute for Food and Drug Control;3.Shanghai Huayu Pharmaceutical Company Limited;Analysis of the contents of Imperatorin and Isoimperatorin in Radix Glehniae from different sources[J];Shanghai Journal of Traditional Chinese Medicine;2011-02
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