Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Remedies & Clinics》 2007-11
Add to Favorite Get Latest Update

Study on the proliferative inhibition and apoptosis of human gastric cancer cells with treatment of caesalpinia sappan L. extract

WANG Xue*, ZHAO Su-lian, XU Jian-guo, ZHAO Ying-fang. *Department of Immunology, Shanxi Medical University, Taiyuan 030001, China  
Objective To illustrate the growth inhibition and apoptosis in human gastric cancer (SGC-7901) cells treated with extracts of caesalpinia sappan L. Methods The growth curve was mapped according to cell counts to reflect the proliferation of cancer cells. Morphological changes of cells were observed by means of HE staining and fluorescence staining. DNA ladder was examined by DNA agarose gel electrophoresis. Results The growth curve of the cell line showed inhibitory effects of Caesalpinia sappan L. extracts on cell proliferation. Changes in morphology typical of apoptosis were observed 48 h following treatment with caesalpinia sappan L. extracts, which appeared somewhat dose-dependent. Typical DNA ladders were identified with agarose gel electrophoresis. Conclusion Caesalpinia sappan L. extracts may obviously inhibit SGC-7901 cell proliferation and induce cell apoptosis.
【Key Words】: Apoptosis Caesalpinia sappan L. extracts Gastric cancer cells
【CateGory Index】: R735.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 1 Hits
1 WU Hui-hui~1,HOU Xiu-liang~1,ZHANG Xin-long~2,GAO Wei-dong~1,GAO Hai-yan~3(1.Key Laboratory of Science and Technology of Eco-Textile,Ministry of Education,Jiangnan University,Wuxi 214122,China;2.Heilan Group,Jiangyin 214426,China;3.School of Chemical and Material Engineering,Jiangnan University,Wuxi 214122,China);Extraction process of Sappan Wood Dye and its dyeing properties to wool fabrics[J];Wool Textile Journal;2009-10
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 WU Zhi-li1,SUN Guo-ping1,WU Qiang2,FAN Lu-lu1,FU Wei-zheng1(1.Department of Oncology,The First Affiliated Hospital of Anhui Medical University,Hefei,Anhui 220022,China;2.Department of Pathology,Anhui Medical University,Hefei 230032);Expression and its correlation of Cox-2 and Her-2/neu in gastric carcinoma tissues[J];Anhui Medical and Pharmaceutical Journal;2010-10
2 ZHANG Xue Mei1, 2△, MIAO Xiao Ping2△, XIONG Ping2, YU Chun Yuan2, TAN Wen2, QU Shi Ning2, SUN Tong2, ZHOU Yi Feng2, LIN Dong Xin21.Department of Biological Sciences,North China Coal Medical College,Tangshan,Hebei,063000,P.R.China2.Department of Etiology &Carcinogenesis,Cancer Institute,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,100021,P.R.China;Association of Functional Polymorphisms in Matrix Metalloproteinase-2 (MMP-2) and MMP-9 Genes with Risk of Gastric Cancer in A Chinese Population[J];Chinese Journal of Cancer;2004-11
3 ZHAO Fu-you,WANG Zi-an,ZHENG Rong-sheng(Department of Medical Oncology,The First Affiliated Hospital of Bengbu Medical College,Bengbu Anhui 233004,China);Efficacy of calf spleen extraction injection combined chemotherapy in the treatment of andvanced gastric cancer[J];Journal of Bengbu Medical College;2010-08
4 CUI Xiao-wei,ZHANG Qing-yu,ZHAO Feng-juan,LIU Jian,SONG Xiao-mei.Department of Gastroenterology,Tianjin Medical University General Hospital,Tianjin(300052),China;KANG Chun-sheng.Department of Neurosurgery,Tianjin Medical University General Hospital and Laboratory of Neuro-Oncology,Tianjin Neurological Institute,Tianjin(300052),China;Growth inhibition effect of small interfering RNA on tumor growth of human gastric caner cell SGC7901 targeting Akt1[J];International Journal of Digestive Diseases;2009-03
5 PENG Xiao-chun (Medical School of Yangtze University, Jingzhou 434023, China)ZHANG Jing-wei (Department of Tumor Surgery of Zhongnan Hospital,Wuhan University,Wuhan 430071, China)WEI Lei (Department of Pathophysiology, Medical College of Wuhan University, Wuhan 430071, China);Study of Expression of VASP in Gastric Carcinoma[J];Journal of Yangtze University(Natural Science Edition);2009-02
6 HUANG Xi*,LIU Juan,WANG Xin-yun,ZHENG Hai-yan,ZHU Cong-zhong,LI Yun,LI Fang*Department of Pathology,Tianjin Medical University,Tianjin 300070,China;Analysis of clinical pathological features of 7 540 cases of gastric tumors[J];Clinical Focus;2008-23
7 WANG Si-ping,ZHU Yan (Department of General Surgery,Suzhou Wuzhong People’s Hospital,Suzhou 215128,China);A Retrospective Analysis on 1371 Cases of Gastric Carcinomas Diagnosed by Gastroscopy[J];Practical Clinical Medicine;2010-03
8 YU Guan-zhen,CHEN Ying,PAN Jun,WANG Xi,WANG Jie-jun.Department of Oncology,the Affiliated Changzheng Hospital,Second Military Medical University,Shanghai 200070,China;The construction of tissue microarrays of Chinese gastric carcinoma and analysis of clinicopathological prognostic factors of gastric cancer patients[J];Chinese Clinical Oncology;2008-08
9 YU Guan-zhen,CHEN Ying,PAN Jun,WANG Xi,WANG Jie-jun.Department of Oncology,the Affiliated Changzheng Hospital,Second Military Medical University,Shanghai 200070,China;The role of ErbB2/Grb2/mTOR pathway in gastric carcinoma[J];Chinese Clinical Oncology;2008-08
10 SHA Jie,LI Xue-liang*,LIN Lin,SHI Rui-hua,HU Xiao-dan(Department of Gastroenterology,the First Affiliated Hospitoal of NJMU,Nanjing 210029,China);Clinical application value of acetic acid and indigo carmine staining in the auxiliary diagnosis of flat gastric lesion[J];Acta Universitatis Medicinalis Nanjing(Natural Science);2011-03
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 WANG San long1,2, CAI Bing1*, CUI Cheng bin1, ZHANG Hua feng1,2, YAO Xin sheng2, QU Ge xia2 1.Laboratory of Molecular Pharmacology, Beijing Institute of Biomedicine, Beijing 100091, P.R.China 2.Laboratory of Botany Chemistry, Shenyang Pharm;Apoptosis Induced by Caesalpinia Sappan L.Extract in Leukemia Cell Line K562[J];Chinese Journal of Cancer;2001-12
2 QIAN Xiao-Ping,LIU Bao-Rui,HU Jing,LI Min,HU Wen-Jing,SUN Jing,YU Li-Xia Cancer Center,Drum Tower Hospital,Medical School of Nanjing University,Nanjing,Jiangsu,210008,P.R.China;Inhibitory Effect of Tetrandrine on Angiogenesis[J];Chinese Journal of Cancer;2008-10
3 GUO Rong-hui, LIU Miao-li, FU Hong-bin(Department of Dyeing and Chemistry, Chengdu Textile College, Chengdu 610023);On Progress of Sappan Plant Dyestuff Application[J];Journal of Chengdu Textile College;2005-03
4 GAO Yong, WANG Jie Jun, XU Qing, YE Qin Qin, GUO Jing, GENG Huai Cheng (Department of Oncology, Changzheng Hospital, Second Military Medical University,Shanghai 200003, China);Inhibitory effect of ginsenoside Rg3 on tumor neoangiogenesis[J];Academic Journal of Second Military Medical University;2001-01
5 ;Study on chemical constituents of Flos Carthami(Ⅱ)[J];Academic Journal of Second Military Medical University;2005-02
6 YU Xiao ping, MI Man tian, ZHU Jun dong (Department of Nutrition and Food Hygiene, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China);Effects of genistein and VEGFR on proliferation of ECV304 cells[J];Acta Academiae Medicinae Militaris Tertiae;2004-08
7 YANG He-ping, LI Jian-ming, TANG Chun-lan, GONG Liang, WANG Hai-jing (Department of Respiratory Diseases, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Role of active components of curcumin in anti-angiogenesis in vitro[J];Acta Academiae Medicinae Militaris Tertiae;2005-11
8 HUANG Li-sha,LU Yu-yun(Department of Chemistry and Chemical Engineering,Foshan University,Foshan 528000,China);Stady on microwave extraction and stability of pigment in Sappan[J];Journal of Foshan University(Natural Science Edition);2007-02
9 YI Cheng, WANG Guo-qing,YI Qiong(Department of Chemotherapy,Center for Cancer,West ChinaHospital, Sichuan University,Chengdu 610041, China);Experimental study on antiangiogenesis of Xue-liu-san[J];The Chinese Journal of Clinical Pharmacology;2004-06
10 KE Gui-zhen LIN Chan-yang XU Wei-lin YU Wei-dong(College of Textiles and Materials,Wuhan Universityof Science and Engineering,Wuhan 430073);Dyeing of Wool Fabric with Natural Plant Dye Sapanwood[J];Dyestuffs and Coloration;2007-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved