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《Drug Evaluation Research》 2016-02
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Research progress on chemical constituents in roots and rhizomes of Polygonum cuspidatum and their pharmacological activities

SHI Sheng-ming;PAN Ming-jia;WANG Wen-qian;WANG Jie;CHEN Chang-qing;Tianjin Institute of Pharmaceutical Research;  
In recent 10 years, the lectures for studies on the roots and rhizomes of Polygonum cuspidatum in both Chinese and foreign periodicals have been retrieved, the chemical constituents isolated and identified from the roots and rhizomes of P. cuspidatum and their pharmacological progress have been analyzed and summarized. There are main anthraquinones, stilbene, flavonoids, coumarins, and some fatty compounds in the roots and rhizomes of P. cuspidatum, which have a variety of pharmacological effects, including anti-inflammation, antivirus, antibiosis, regulation of blood lipid, antithrombosis, change of blood rheology, dilation of blood vessels, protection of myocardium, anti-oxidation, anticancer, improvement of Alzheimer's disease, prevention of AIDS, and so on. The studies on the roots and rhizomes of P. cuspidatum over the years have proven its value and development prospects, and provide the information for the further development and utilization of the roots and rhizomes of P. cuspidatum.
【Fund】: 国家自然科学基金(2711001002001)
【CateGory Index】: R284.1;R285.5
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