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《Progress in Pharmaceutical Sciences》 2012-03
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Recent Researches on the Toxicity of Saponins from Plants

MA Sheng-tang,KOU Jun-ping,YU Bo-yang(Department of Complex Recipes of Traditional Chinese Medicine,China Pharmaceutical University,Nanjing 211198,China)  
Saponins are widely found in plants with diverse chemical structures and multiple biological activities.As major active components from some common Chinese medicinal herbs,some saponins exert anticancer,anti-inflammatory,antimicrobial,immunomodulatory and cardiovascular protection activities and have been widely used clinically.However,systematic knowledge about their toxicity is scarce.The foreign and domestic researches on the toxicity induced by saponins from plants in recent years were reviewed,so as to provide some references for the developmemt and the clinical rational use of saponins-related drugs.
【Fund】: 国家“重大新药创制”科技重大专项(No.2009ZX09103-308 2012ZX09102201-015)
【CateGory Index】: R285.5
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