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《Journal of Pharmaceutical Practice》 2008-03
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Preparation of Puerarin by microemulsion drug delivery system

Chen Han1,Zhong Yan-qiang2,Lu Ying2(1.China;2.College of Pharmacy,Second Military Medical University,Shanghai 200433,China)  
Objective: To develop a microemulsion drug delivery system of Puerarin(PUE-ME).Methods:Formulation of PUE-ME was screened by solubility experiments,compatibility tests and pseudo-ternary phase diagrams,with the consequence of visual examination as parameter.Results: The maximum drug corporation was 77.11 mg/mL.The formulation was composed of IPM(10%),brij-96V(37.5%),ethanol(37.5%),and water(25%).Conclusion:The formulation of PUE-ME preparation could meet the general requirements of the design.
【CateGory Index】: TQ461
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 Lin Ji, Hou Shaozhen, LI Geng, ect(Guangzhou University of Traditional Chinese Medicine, Guangzhou, 510405);An Exploration on Adverse Reaction of Injection Puerarin and Exploitation of Oral Preparation of Puerarin[J];;2005-05
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【Co-citations】
Chinese Journal Full-text Database 2 Hits
1 LI Jian (Zhejiang Chinese Medical University,Hangzhou 310053,China);Research development in flavonoids of puerarin[J];Anhui Medical and Pharmaceutical Journal;2008-12
2 DENG Chang-feng1,2,GONG You-lan1,2,WU Xue1,2,XIANG Da-wei1,2,OU-YANG Li-na1,2,XIANG Da-xiong1,2(1.School of Pharmaceutical Sciences,Central South University,Changsha 410013;2.Department of Pharmacy,Second Xiangya Hospital,Central South University,Changsha 410011);Determination of puerarin in rat plasma after intragastric administration of puerarin microemulsion[J];Central South Pharmacy;2009-07
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1 ;The bioavailability of puerarin microemulsion for oral administration in rats[A];[C];2009
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