Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Acta Pharmaceutica Sinica》 1991-07
Add to Favorite Get Latest Update

APPLICATION OF HIGH SPEED COUNTERCURRENT CHROMATOGRAPHY FOR THE ISOLATION OF NATURAL PRODUCTS——PREPARATIVE ISOLATION OF TAXANE-DITERPENOIDS AND DITERPENE ALKALOIDS

C Rao, X Liu, PL Zhang, WM Chen and QC Fang (Institute of Materia Medica, Chinese Academy of Medical Sciences,Beijing 100050)  
high speed countercurrent chromatography (HSCCC)based on the fundamental principle of liquid-liquid partition is a newly developed technique for isolation. It utilizes a particular combination of coil orientation and planetary motion to produce a unique hydrodynamic phenomenon in the unilateral phase distribution of two immiscible solvents in a coiled column. In recent years HSCCC has gained increasing popularity in the isolation of bioactive natural products.This paper reports its application in the prepartive separation of taxol (1), cephalomannine (2)and baccatin-Ⅲ (3) from the alcoholic extract of Taxus yunnanensis. These 3 ingredients are first obtained from this plant.
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved