Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Acta Pharmaceutica Sinica》 2004-08
Add to Favorite Get Latest Update

Determination of five components in compound hypotensive tablet by HPLC

CHE Bao-quan * (Beijing Institute for Drug Control, Beijing 100035, China)  
Aim To establish a method for the determination of the five components (reserpine, chlordiazepoxide, hydrochlorothiazide, dihydralazine sulfate, triamterene) in compound hypotensive tablet. Methods The chromatography was performed using a CN column with acetontrile-0.1 mol L -1 sodium heptasulfonate solution (7∶3) and (5∶5) as the mobile phases. The detection wavelength was 267 nm for reserpine, chlordiazepoxide and hydrochlorothiazide, 310 nm for dihydralazine sulfate, 360 nm for triamterene. Results The linear range of each component was tested, and the recovery and stability of each component was satisfactory, three lots of samples were determined using the method. Conclusion This is an accurate and credible quality control method for compound hypotensive tablet.
【Key Words】: compound hypotensive tablet HPLC reserpine triamterene hydrochlorothiazide chlordiazepoxide dihydralazine sulfate
【CateGory Index】: R927.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 10 Hits
1 PAN jing-lan (Guangzhou Xingqun Pharmaceutical Co.Ltd.,Guangzhou,Guangdong 510288,China);Simultaneous determination of hydrochlorothiazide,dihydralazine sulfate and triamterene in compound hypoensive tablets by HPLC[J];Journal of Guangdong College of Pharmacy;2008-03
2 JI Wan-li1,ZHAO Jia-tai2(1.Shanxi Changzhi Institute for Drug Control,Changzhi 046000,China;2.Shanxi Taihang Pharmaceutical Co.Ltd,Changzhi 046000,China);Determination of dihydralazine sulfate in compound kendir tablets (II) by HPLC[J];Strait Pharmaceutical Journal;2008-01
3 Wanli Ji1, Jiatai Zhao2 (Shanxi Changzhi Institute for Drug Control, Changzhi 046000;Shanxi Taihang Pharmaceutical Co.Ltd, Changzhi 046000);Determination of Dihydralazine Sulfate of Compound Kendir Tablets (II) by HPLC[J];Life Science Instruments;2007-12
4 LIU Hai-ying HUANG Li YANG Ning MIAO Ai -dong SU Fang SHEN Zhen -hua (Institute tot Drug and Instrument Control of United Logistics Department of Beijing Command of PLA,Beijing 100071,China);HPLC determination of five characteristic constituents in compound pargyline tablets[J];Chinese Journal of Pharmaceutical Analysis;2008-08
5 XU Bo~1 CHANG Ling~1 GAO Ling~2(1.Guizhou Province Institute for Drug Control,Guiyang 550004,China;2.The Remin Hospital of Guizhou Province,Guiyang 550002,China);HPLC determination of vitaminB_1,vitaminB_6,pantothenic acid and hydrochlorothiazide in compound reserpine tablets[J];Chinese Journal of Pharmaceutical Analysis;2008-11
6 JIN Peng-fei,YAN Xiao-yan,KUANG Yong-mei,ZOU Ding,HU Xin,SUN Chun-hua(Department of Pharmaceutical Science,Beijing Hospital,Beijing 100730,China);HPLC dtermination of reserpine in compound hypotensive tablets[J];Chinese Journal of Pharmaceutical Analysis;2010-07
7 WU Hongying1,FAN Yufeng2(1.Institute for Food and Drug Control of Xinyang City,Xinyang 464000,China;2.Affiliated Hospital of Xinyang Polytech-nic of Henan Province,Xinyang 464000,China);Analysis of dihydralazine sulfate in compound reserpine tablets by reversed phase ion pair chromatograpy[J];China Modern Medicine;2009-16
8 MAO Guifu,GUO Tao(Dept. of Pharmacy,The General Hospital of Shenyang Military Region,Shenyang 110016,China)MAO Guifu(Shenyang Pharmaceutical University,Shenyang 110016,China);Determination of Three Components in Compound Hypotensive Tablet by RP-HPLC[J];China Pharmacy;2007-22
9 GAO Qing, ZHANG Zhe, DAI Hong, CHE Bao-quan, GUO Hong-Zhu (Beijing Institute for Drug Control, Beijing 100035);Detection of Antihypertensive Agents Illegally Added in Traditional Chinese Medicine and Health Care Products by LC-MS/MS[J];Chinese Journal of Pharmaceuticals;2007-05
10 WANG Ying 1,2,WANG Wei-hong 1,NIE Lei1 (1.School of Pharmaceutical Sciences,Shandong University,Jinan 250012;2.Shandong Drug and Food Vocational College,Zibo 255011);Determination of Six Components in Compound Reserpine Tablets by Partial Least Square Method[J];Chinese Journal of Pharmaceuticals;2009-10
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 FANG Chuan-dai et al (Institute Technology,Yichun University,Yichun,Jiangxi 336000);Study on RP-HPLC Method for Determination of Two Flavone Compounds of Flos lonicerae[J];Journal of Anhui Agricultural Sciences;2006-11
2 YANG Xi-xiang, CAI Yong-qing (Huai'nan instiute for drug control, Huai'nan 232007,China);Determination of aciclovir in aciclovir ointment by HPLC[J];Anhui Medical and Pharmaceutical Journal;2005-02
3 LI Rong, LI Jun (School of Pharmacy, Anhui Medical University , Hefei 230032,China);Advances in pharmacological research and structure-activity relationship of flavonoids[J];Anhui Medical and Pharmaceutical Journal;2005-07
4 WANG Gui_fen *,PIAO Yuan_zhe (Department of Chemistry,College of Science and Technology, Yanbian University,Yanji 133002);Determination of Diclofenac in Voltalin Tablets by Differential Pulse Voltammetry[J];ELECTROCHEMISTRY;2000-01
5 NI Hong-gang, ZHANG Hong-fang, ZHENG Jian-bin~*(Institute of Analytical Science, Shanxi Provincial Key Laboratory of Electroanalytical Chemistry, Northwest University, Xi'an 710069, China);Oscillographic Determination of Ethamsylate[J];Electrochemistry;2005-02
6 ZHANG Gui-Ping1, LI Yin-Yan2, Lv Jia-Chun3, OU Hui-Jian1 1Department of Pharmacology, 2Department of Cell Biology, 3Institute of Chemical Carcinogenesis, Guangzhou Medical College, Guangzhou 510182, China;Ursolic acid induces apoptosis through effects on Bax and Bcl-2 expression in human MCF-7 cells[J];Journal of The Fourth Military Medical University;2005-20
7 LIANG Gailing,ZHAO Meihua~(1),ZHONG Ping.Henan Province Institute for Drug Control,Zhengzhou 450003;1) Institute of Biology,Heanan Academy of Science,Zhengzhou 450003,Henan;HPLC determination of Vitamin B_2 in Weimeisu tablets[J];Clinical Medicine;2005-10
8 HUANG Jian-lin~1,ZHANG Zhan-xia~2(1.School of Chemistry and Material,Hubei University,Wuhan 430062,China;2.School of Chemistry and Chemical Engineering,Zhongshan University,Guangzhou 510275,China);The Simultaneous Determination of Oleanolic and Ursolic Acid in Guava Leaves by Gas Chromatography-Mass Spectrometry[J];Analysis and Testing Technology and Instruments;2005-03
9 Wang Yong, Zhang Zhuoyong, Liu Sidong, Guo Liping (Department of Chemistry, Northeast Normal University, Changchun 130024);Non-linear Calibration in Analytical Chemistry[J];Chinese Journal of Analytieal Chemistry;1998-09
10 Xu Qijin; Huang Junxiong (Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences,Beijing 100085);Regeneration of High Performane Ion Exchange Chromatographic Colunm in Protein Separations and Purifications[J];CHINESE JOURNAL OF ANALYTIEAL CHEMISTRY;2000-01
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 CHENG Zheng,WAN Qing,GUAN Yu-yun,WU Ling(Tongling Institute for Drug Control,Tongling,Anhui 244000,China);Determination of hydrochlorothiazide,promethazine hydrochloride and reserpine in compound reserpine tablets by HPLC[J];Anhui Medical and Pharmaceutical Journal;2010-01
2 CHAI Yi-feng*,ZHU Zhen-yu and CHEN Xiao-fei(Department of Pharmaceutical Analysis,School of Pharmacy,Second Military Medical University,Shanghai 200433),Fenxi Shiyanshi,2010,29(9):78~122;Pharmaceutical analysis(I)[J];Chinese Journal of Analysis Laboratory;2010-09
3 ZHU Wei-Wei WANG Qia DENG Xi-Chao SU Danb(Department of Chemistry and Life Science,Hechi Universtiy,Yizhou,Guangxi 546300,P.R.China)a(Research Center for Analysis and Measurement,Kunming University of Science and Technology,Kunming 650093,P.R.China)b(Kunming Dianhong Pharmaceutical Co.Ltd,Kunming 650000,P.R.China);Determination of Reserpine in the R.vomitoria Roots from Different Producing Areas by HPLC[J];Chinese Journal of Spectroscopy Laboratory;2011-02
4 WU Yong (Maanshan Institute for Drug Control,Maanshan 243000,China);Determination of dihydralazine sulfate in compound reserpin tablets by HPLC[J];Anhui Medical and Pharmaceutical Journal;2011-06
5 CHENG Min(Food and Drug Control Institute,Huaibei,Anhui Province 235000);Determination of vitamin B_1,vitamin B_6 and acidum nicotinicum in pediatric compound four vitamins and ferrous fumarate powder by HPLC[J];Anhui Medical and Pharmaceutical Journal;2011-06
6 JIANG Jian-hui(College of Life Sciences,Tarim University,Alar 843300,China);Research Progress in the Synthesis of Indole Alkaloids[J];Guangzhou Chemistry;2011-02
7 ZHANG Zheng (Ma′anshan Institute for Drug Control,Ma′anshan 243000);Hydrochlorothiazide and dihydralazine sulfate in compound reserpin tablets simultaneously determined by HPLC[J];Anhui Medical and Pharmaceutical Journal;2011-10
8 JI Wan-li1,ZHAO Jia-tai2(1.Shanxi Changzhi Institute for Drug Control,Changzhi 046000,China;2.Shanxi Taihang Pharmaceutical Co.Ltd,Changzhi 046000,China);Determination of dihydralazine sulfate in compound kendir tablets (II) by HPLC[J];Strait Pharmaceutical Journal;2008-01
9 Li Jiayu,Wang Haibin,Liu Zhihua,Chen Rongshan,He Haibin(School of Life Sciences,Fujian Agriculture and Forestry University,Fuzhou 350002,China);The structure,biosynthesis,and function of plant secondary metabolism compounds——Alkaloid[J];Journal of Agricultural Sciences;2009-04
10 CHENG Ai-ping,OU Bei-li,ZHANG Zhan-huang,SHEN Chun-yan,ZHU Shan-yin(Jaxing Institute for Food and Drug Control,Zhejiang Jiaxing 314000);Determination of 11 Antihypertensive agents in Chinese patent medicine by UPLC-MS/MS[J];Strait Pharmaceutical Journal;2011-07
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved