I SOLATION AND STRUCTURAL ELUCIDATION OF FOUR NEW TAXANE DITERPENOIDS FRON TAXUS YUNNANENSIS
WM Chen,PL Zhang and JY Zhou(Institute of Materi Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050)
Seven taxane diterpen oids and alk aloids have been isolated from the ethanolicextract of the bark of Taxus yunnanensis Cheng et L.K.Fu. Three were identified as the known taxanes:5-decinnamovyl taxinineJ ( III),7-xylosyl taxol(V)and 7-xylosyl cephalomannine(VI ).Thestructures of four new compounds were elucidated as 5- decinnamoyl-11-acetyl-19- hydroxy taxagifine(I),2- deacety-5- decinnamoyltaxinine J(II ,1-hydroxy-2,7,9-trideacetylbaccatin I(IV )and7- xylosyl-10- deacetoxybaccatin III(VII)by spectroscopic methods(MS,1H NMR,1H-1H COSY,13CNMR, 13C-1HCOSY).
【CateGory Index】： R284.2