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《Contemporary Medicine》 2008-06
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TNFa在胎膜早破合并宫内感染的作用

Objective to evaluate the effect of tumor necrosis factor(TNF)-a in the etiology and pathogenesis of premature rupture of membranes,(PROM).Methods therewere 67 normal pregnant women who were requested terminated pregnancy with cesarean section.they were divided into three groups:PROMgroup(35cases),Preterm PROM group(15cases)andControlgroup(17cases).The enzyme linked immunosorbent assay was employed to detect the concentration of TNF-a.In the meantime,histological change and pathological.change were observed with hematoxylin and eosin.Resuhs the concentration of TNF-a in PROM is more than that in control group(P0.05).the density of TNF-a of in- fected menbranes was more than that of not-infected menbranes.Conclusion TNF-a played important role in the etiology and pathogenesis Of PROM.
【CateGory Index】: R714.433
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 Deng Feitao, Lu Qiuyun Department of Obstetrics and Gynecology, Xiehe Hospital, Tongji Medical University Wuhan 430022 Department of Obstetrics and Gynecology, Tongji Hospital,Tongji Medical University Wuhan 430030;Interleukin-6 Levels in Maternal Serum, Umbilical Cord Serum and Amniotic Fluid in Patients with Premature Rupture of Membranes and Clinical Implication[J];Acta Universitatis Medictnae Tangji;2000-06
【Co-citations】
Chinese Journal Full-text Database 4 Hits
1 Zhang Lingling1,Zhang Xiong2,Li Rong11Department of Obstetrics and Gynecology,2Department of Laboratory,Wuchang Hospital of Wuhan City,Wuhan 430063;Changes of Zn,Cu,TNF-α and Apoptosis Index in Premature Rupture of Membranes[J];Acta Medicinae Universitatis Scientiae et Technologiae Huazhong;2007-05
2 WEI Hong-wei, LEI Zhi-ying, LUO Zhang-wei, QU De-ying, SHI Gui-ling, XIE Li-ling (Affiliated Hospital of Youjiang Medical College for Nationalities, Bose, Guangxi 533000, P.R.China);Interleukin-6 levels in amniotic fluid in pregnant women with premature rupture of fetal membranes[J];Journal of Youjiang Medical College For Nationalities;2002-02
3 Huang Jinna~ * , Li Yuancheng Department of Obstetrics and Gynecology, People's Hospital of Chaonan District, Shantou 515144,China;Evaluation of matrix metalloproteinase-9 and tumor necrosis factor-α in predicting chorioamnionitis in patients with premature rupture of membranes[J];Chinese Journal of Practical Gynecology and Obstetrics;2006-06
4 HUANG Jin-na LI Yuan-cheng ZHEN Li-xuan GUO Shi-xian GAO Chang. Department of Obstetric and Gynecology,People's Hospital of Chaonan District Shantou,Guangdong 515144,China;The study of matrix metalloproteinase-9 and tumor necrosis factor-or in predicting chorioamnhionitis in patients with premature rupture of membranes[J];Chinese Journal of Primary Medicine and Pharmacy;2007-10
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 Deng Feitao, Lu Qiuyun Department of Obstetrics and Gynecology, Xiehe Hospital, Tongji Medical University Wuhan 430022 Department of Obstetrics and Gynecology, Tongji Hospital,Tongji Medical University Wuhan 430030;Interleukin-6 Levels in Maternal Serum, Umbilical Cord Serum and Amniotic Fluid in Patients with Premature Rupture of Membranes and Clinical Implication[J];Acta Universitatis Medictnae Tangji;2000-06
2 Zhang Yingyuan, Zhang Qing, Xu Zhen, et al. Institute of Antibiotics of Huashan Hospital, Shanghai Medical University, Shanghai 200040;Tissue and Body Fluid Distribution of Antibacterial Agents in Pregnant and Lactating Women[J];Chinese Journal of Obstetrics And Gynecology;1997-05
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