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The Influences of Ultra-early Cranioplasty on Cerebral Hemodynamics and Brian Function

Jin Panpan;Hu Fei;Jiang Yong;Yangtze River Shipping General Hospital/Wuhan Brain Hospital;  
Objective To observe the influence of ultra-early cranioplasty on cerebral hemodynamics and brian function. Methods 39 patients who underwent cranioplasty were divided into ultra-early group and control group according to time interval from cranioplasty to first craniotomy. Cerebral hemodynamics,neurological and cognitive function before and after cranioplasty surgery in the two groups were compared and analyzed respectively. Results There was no significant difference on rCBV and TTP before and afer surgery in ultra-early group( P 0.05). The changes of rCBF at injured side cortex and basal ganglia region were more in ultra-early group than those in control group(P 0. 05). The changes of MTT in ultra-early group were greater than those in control group in deep thalamus with no significant difference( P 0. 05). There were significant differences on changes of MTT in basal ganglia region between the two groups( P 0. 05). There was no significant difference on changes of TTP between the two groups(P 0. 05). NIHSS and CSS scores in ultra-early group were significantly lower than those in control group( P 0. 05).Conclusion Ultra-early cranioplasty can significantly improve blood perfusion of the brain, and is beneficial to the recovery of neurological function.
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