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《Medical Recapitulate》 2013-09
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Research Progress and Clinical Application of α-L-fucosidase

WU Man-dan,HUANG Qian-chuan.(Department of Laboratory Medicine,Wuhan General Hospital of Guangzhou Military Area,Wuhan 430070,China)  
The acid α-L-fucosidase(AFU) is usually found as a soluble component of lysosomes,the systematic name is α-L-fucosidase(EC3.2.1.51).It is involved in the hydrolytic degradation of fucose-containing molecules.AFU distributes in human tissues and body fluids,especially high concentration is seen in the liver and kidney.Alterations in the activity of AFU in serum or tissue have been observed in cancer.AFU is a significant index for the diagnosis,therapeutic effect and prognosis of hepatocellular carcinoma,pancreatic adenocarcinoma,and colon adenocarcinoma.
【CateGory Index】: R730.5
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 ZHOU Yong-lie,SHAO Zhe-xin,GAO wei,et al.(Clinical Laboratory Medicine Center of ZheJiang Provincial Hospital,Hangzhou 310014,China);The value of integral method with the six tumor markers in the diagnosis of primary hepatic cancer[J];Chinese Journal of Laboratory Diagnosis;2006-03
2 DONG Huai-ping,WANG Li,ZHAO Qi-gang,et al.(Hospital of Puple of Liaocheng city Shandong Province 252000,China);The clinical value of the combined detection of AFU,AFP-L3 and HCY in the diagnosis of primary hepatic cancer[J];Chinese Journal of Laboratory Diagnosis;2007-04
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Xie Guoqiang,Shao Yaoming,Yangyan Department of Laboratory Medicine,Wuxi Municipal People's Hospital,Wuxi Jiangsu(214000);Study on Clinical Significance of Determination of Changes of Serum TGF-α,TGF-β1,AFU and AFP Levels in Patients with Hepatocellular Carcinoma and Liver Cirrhosis[J];Journal of Radioimmunology;2009-03
2 Wang Pengbo,et al.Oncology Department,The Affiliated Hospital of Medical College Qingdao University.Qingdao,266100;Early Diagnostic Value of Combined Examination of Tumor Markers in Primary Hepatocellular Carcinoma[J];Qingdao Medical Journal;2011-02
3 ZHANG Fu-jie,JIANG De-qing,LI Da-zhu,et al.Department of General Surgery,Affiliated Lianyungang Hospital of Bengbu Medical College,Lianyungang 222006,Jiangsu,China;Clinical Value of Determination of IL-6,IL-18 and IL-18 BP in Patients with Primary Liver Cancer[J];Chinese Journal of General Practice;2012-08
4 DONG Le,WANG Yanmei,LI Hui,and MA Xueping.Beijing Health School,Beijing 100053,China;Determination of IL-6,ceruloplasmin and AFP in diagnosis of primary hepatic cancer[J];Medical Journal of the Chinese People's Armed Police Forces;2008-06
5 DU Xian,LI Shi-kui,HUANG Sheng-xian.Department of Laboratory Medicine,the Second People's Hospital of Nanning,Nanning,Guangxi 530031,China;Expression and significance on homocysteine in primary hepatic carcinoma[J];Modern Preventive Medicine;2012-13
6 DAI Xiaoyun(Runzhou People's Hospital of Zhenjiang, Zhenjiang 212004, China);Combined Detection of Tumor Markers in the Diagnosis of Primary Hepatic Cancer and Its Value of Application[J];Clinical Medical & Engineering;2011-10
7 YANG Jun Department of Nuclear Medicine,The Third People's Hospital in Honghe State of Gejiu,Yunnan 661000;Diagnostic Value of Combined Determination of Tumor Markers in Patients with Primary Hepatic Carcinoma[J];China Modern Doctor;2008-05
8 XU Chengxin1 LIN Li1 SHI Qingxin1 ZHANG Gui2 1.Taizhou Hospital in Zhejiang Province,Taizhou 317000,China;2.Taizhou Hospital of TCM in Zhejiang Province,Taizhou 318001,China;Application Value of Combination of AFP-L3、AFP and Ferritin in Diagnosis of Liver Cancer[J];China Modern Doctor;2011-18
9 Dong Lei1,Liu Juan2,Ma Hongyu1,Quan Shouzhen1,Zhu Meicai1 1.Clinical Test Center;2.Department of Blood Transfusion,General Hospital of the Air Force,Beijing,100142,China;Clinical significance of detection of α-L-fucosidase in patients with hematopathy[J];Medical Journal of National Defending Forces in Southwest China;2012-10
10 Liu Zhengjiang,Zhou Chu,He Yajun,Xue Kedong.Medical Intensive Care Unit,Xinjiang Uygur Autonomous Region People′s Hospital,Xinjiang 830001,China;Multivariate Analysis of Uygur,Han Nationality Death Patients in ICU Patients:A Retrospective Analysis[J];Journal of Medical Research;2013-02
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 LI Qing-lin,YE Yue-hong,TANG Bo(Department of Clinical Laboratory,Second College of Clinical Medicine,Chongqing University of Medical Sciences,Chongqing 400010,China);Diagnostic value of multiple combined detection indexes in liver diseases[J];Chongqing Medicine;2007-10
2 Ynagguo Hui;et al (Department of Internal Medical, Affiliated Hospital,Guiyang medical College);Serum Sialic and α-Fucosidase Measurement and Their Clinical Significance in Patient Lung Diseases[J];GUIZHON MEDICAL JOURNAL;1998-05
3 ZHANG Ming-zhu,HE Guang-yuan,Qin qiang,et al.(Shunde Hosp.of Combination of TCM with Western Medicine,Foshan 528333,China);The correlation between the activity of serum α-L-Fucosidase and type B hepatitis[J];Ningxia Medical Journal;2007-05
4 Chang Liangang(The hospital of Feicheng coal Ltd.Feicheng Shandong 271608);Clinical significance of determination of urine α-L-Fucosidase activity in patient with renal tubular injury[J];Medical Laboratory Science and Clinics;2006-04
5 He Qian Liu Yujing Zhao CaileiDepartment of Clinical Laboratory , the Second Hospital of Xi'anJiaotong University(Xi'an 710004);Study of a-L-fucosidase during the course of forming SD rats PHC induced by DEN[J];Shaanxi Medical Journal;2005-05
6 Zhou Yonglie,Li Weixing(Zhejiang Provincial People’s Hospital,Hangzhou 310014);Clinical Significance of Determing Serum α L Fucosidase in Patients with Diabetes Mellitus[J];MODERN DIAGNOSIS & TREATMENT;1997-06
7 WANG Zi-wei,ZHUO Guang-chao,LENG Jian-hang,et al.;The Measurement of Serumα-Fetoprotein(AFP)Variants by Affinity -absorbent Assay[J];Bulletin of Chinese Cancer;2003-02
8 JIANG Jing-ting, WU Chang-ping, DENG Hai-feng,WU Jun, JI Mei,ZHANG Hong-yu,SUN Wen-hui,CHEN Guo-jin,WU Ai-zhen. Department of the Tumor Biological Treatment, The Third Affiliated Hospital of Suzhou College, Changzhou 213003,China;Detection of the diagnosis about pancreatic cancer with the 3 tumor markers in serum[J];Chinese Journal of Laboratory Medicine;2003-07
9 WANG Guo-hong,WAN Wen-hui, LIU Bo,LIU Juan,ZHANG Shu-geng,LIANG Zhen,YANG Jiang-ying,ZHANG Jing,DONG Da-hai.Beijing University School of Oncology, Beijing Institute for Cancer Research, Beijing Cancer Hospital, Clinical Laboratory, Beijing 100036,China;To investigate the clinical value of four tumor markers in non-small cell lung cancer[J];Chinese Journal of Laboratory Medicine;2003-08
10 ZHOU Shao-ling,CHEN Shu-lin.Department of Endocrinology,Yuhuangding Hospital Affiliated Qingdao University,Yantai 264000,China;Analysis of correlative risk factors of early diabetic nephropathy in patients with type 2 diabetes mellitus[J];Chinese Journal of Clinicians(Electronic Version);2009-02
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