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《Herald of Medicine》 2003-09
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Effects of Qijianxiaoyingtang to Mice Thyroiditis on Apoptosis and Ultrastructure

HUA Chuan 1, CHEN Ru-quan 2(1. Department of Surgery,the First Clinical Medicine College Nanjing University of Traditional Chinese Medicine,Nanjing 210029, China ;2. Department of Internal Medicine,Hubei Hospital of Traditional Chinese Medicine,Wuhan 430061, China )  
Objective:Observe the effects and mechanism of qijianxiaoyingtang to EAT in murine. Method:Injection of hTg and CFA can induce EAT. Monitor the thyroid cell apoptotic ratio by TUNEL. Observe the ultrastructure pathology of mice thyroid with TEM. Results:The apoptosis of thyroid cell in the model group was inhibited ( P 0.01). The rate of apoptotic cell in BQJ was higher than that of model group ( P 0.01). It was high in TT group than that in model group ( P 0.05). The change of thyroid ultrastructure in qijianxiaoyingtang groups can be weakened. Conclusion: Qijianxiaoyingtang can adjust autoimmune disorder in EAT, induce thyroid cell apoptosis, improve the ultramicroscopic athological changes.
【CateGory Index】: R285
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