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《Herald of Medicine》 2004-02
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Puerarin in the Treatment of 42 Cases of Acute Cerebral Infarction

CAO Xue-bing, LIU Chang-qin, YUAN Guang-lei(Department of Medica l Neurology, Union Hospital Affiliated with the Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022 China)  
Objective:To survey the effect of puerarin o n hemorrheology and fibrin monomer polymerization in patients with acute cerebral infarction. Methods:84 cases of acute cerebral infarction were rando mly divided into 2 equal groups, the puerarin group and the control group. Patie nts of the control group were treated with conventional measures including dehyd ration, brain protection, amelioration of microcirculation ect.. On the basis of these measures, patients of the puerarin group were given each 250 mL (600 mg) of puerarin administered by intravenous instillation q.d. for 10 consecution day s. Hemorrheology and fibrin monomer polymerization were assayed before as well a s on day 10 of the treatment. Results:The overall effectives rates in the puerarin gro up and control group were 95.23% and 76.19%, respectively(P0.05). Hemorrhe ology and the function of fibrin monomer polymerization in patients of the puera rin group were significantly ameliorated as compared with those of the control g roup(P0.01). Conclusion:Puerarin was shown to be effective in the tre atment of acute cerebral infarction possibly by improving hemorrheology and the function of fibrin monomer polymerization.
【CateGory Index】: R743.3
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