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《Herald of Medicine》 2012-08
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Experimental Study on Anti-inflammatory and Analgesic Effects of Different Extracts from Chinese Lobelia

HUANG Li-de1,GUO Li-qiang2,PAN Ting-qi1,PAN Xi-ying1,YAN Zu-di1,LIU Sheng-li1,ZHAO Shan-min3,HE Xian-jiao3(1.School of Clinical Medicine;2.School of Clinical Laboratory Medicine;3.School of Basic Medicine,Youjiang Medical University for Nationalities,Baise 533000,China)  
Objective To study analgesic and anti-inflammatory effects of different extracts from Chinese lobelia.Methods Water extract and 75% alcohol extract were obtained from Chinese lobelia.Anti-inflammatory effect of Chinese lobelia was studied by using mouse abdominal cavity capillary permeability increase test induced by acetic acid,mouse auricle swelling test induced by xylene,mouse toe swelling test induced by 10% albumen test in mice.Analgesic action of Chinese lobelia was studied by mouse aceticacid-induced twisting test and hot plate test.Results In the same dose,the water extract of Chinese lobelia significantly inhibited the twisting effect induced by acetic acid in the mice(P0.01).The extracts of Chinese lobelia increased the threshold of pain in the mice significantly by hot plate test,after the treatment for 1 h or 2 h(P0.05,P0.01).The extracts of Chinese lobelia inhibited xylene-induced mouse auricle swelling(P0.05).The extracts of Chinese lobelia also significantly inhibited 10% albumen-induced mouse toe swelling,0.5 h,1 h,2 h or 4 h after the induced inflammation(P0.05,P0.01).Conclusion Chinese lobelia has obvious analgesic and anti-inflammatory effects.
【Fund】: 右江民族医学院2010~2012年度普高学生科研项目(右医科字[2010]9号)
【CateGory Index】: R285.5
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Chinese Journal Full-text Database 1 Hits
1 JIANG Yi-ping,XU Jiang-ping,HUANG Fang(Department of Pharmacology,School of Pharmaceutical Sciences,Southern Medical University,Guangzhou 510515,China);Heat-clearing And Detoxifying Effects of Eupatorium chinense L.[J];Herald of Medicine;2013-05
Chinese Journal Full-text Database 7 Hits
1 ZHANG Yong-kang,HE Sheng-hu,LI Yong (Department of Animal Science,Agricultrue Academy,Ningxia University,Yinchuan,Ningxia,750021,China);Study on Ache Easing and Anti-inflammafory Effect of Cynanchum komanovii[J];Progress in Veterinary Medicine;2006-11
2 LI Lanfang,LI Cunman,ZHANG Qinzeng,et al.Hebei Academy of Medical Sciences,Shijiazhuang 050021,China;Effects of extract from Medicago sativa L. on infammation and pain in rats and mice[J];Hebei Medical Journal;2010-07
3 PAN Han-qing,YU Yan-li,ZHANG Li,XIE Ji-qing,BI Yun-sheng(Department of Pharmacy,Jinan Military General Hospital,Jinan 250031,China);Experimental Study On the Analgesic Effect of Xuanqi Drop Pills[J];Herald of Medicine;2007-03
4 GUO Qiang,LI Meng-quan,ZHAO Yu-jia,LI Hou-zhong,JIN Xiu-dong( The Pharmaceutical Department of Mudanjiang Medical College,157011,China);Anti-inflammatory Effect of Keerkang Oral Liquid[J];Herald of Medicine;2010-08
5 HUANG Shan1,2,JIANG Chun-yan2,LONG Fei3(1.Department of Pharmacy,College of Chemical Engineering,Qingdao University of Science and Technology,Qingdao 266042,China;2.Tibet Tianzhi Pharmaceutical Co.,Ltd,Rikeze 857000,China;3.Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China);Anti-Inflammation and Analgesic Effect of Volatile Oil from Nepeta Angustifolia[J];Herald of Medicine;2011-10
6 YAN Qin-yuan,LI Ling-yun(School of Medical Science of Hubei Polytechnic Institute,Xiaogan 432000,China);Anti-inflammation,Analgesia and Skin Irritancy of Nimesulide Ethosomes[J];Herald of Medicine;2011-11
7 JIANG Yanyan,SHI Renbing,LIU Bin,WANG Qiuying,DAI Ying(School of Chinese Pharmacy,Beijing University of Chinese Medicine,Beijing100102,China);Studies on chemical components of Lobelia chinensis[J];China Journal of Chinese Materia Medica;2009-03
Chinese Journal Full-text Database 10 Hits
1 LI Jie-yu et al(Department of Pharmaceutics,Hunan University of Traditional Chinese Medicine,Changsha,Hunan 410208);Optimization of Reflux Extraction Process for Toosendanin from FRUCTUS TOOSENDAN[J];Journal of Anhui Agricultural Sciences;2011-08
2 YANG Yue-e et al(College of Pharmacy,Dali University,Dali,Yunnan 671000);Determination of Five Anthraquinones in RADIX ET RHIZOMA RHEI from Genuine Producing Area[J];Journal of Anhui Agricultural Sciences;2011-11
3 LIU Yong et al(Jiangxi University of Traditional Chinese Medicine,Nanchang,Jiangxi 330006);Comparison Study on Pollen Morphology of Wild Eructus rutaecarpa(Juss.) Benth and E. rutaecarpa(Juss.) Benth.var.officinalis(Dode) Huang in Jiangxi[J];Journal of Anhui Agricultural Sciences;2011-11
4 ZHOU Ping et al(College of Pharmacy,Dali University,Dali,Yunnan 671000);Determination the Content of Astragaloside Ⅳ in Dreg of RADIX ASTRAGALI[J];Journal of Anhui Agricultural Sciences;2011-13
5 HE Rui et al(Research Centre of Chinese Herbal Resource Science and Engineering,Guangzhou University of Chinese Medicine,Key Laboratory of Chinese Medicine Resources of Ministry of Education,Higher Education Megacentre,Guangzhou,Guangdong 510006);Study on the Grading Standard of Andrographis paniculata Seeds[J];Journal of Anhui Agricultural Sciences;2011-24
6 YANG Fan et al(The Department of Chemistry,Changchun Normal University,Changchun,Jilin 130032);Optimization of the Extraction Technology of Total Alkanoids from Radix Sophorae Tonkinensis with Ultrasonic Extraction Technology[J];Journal of Anhui Agricultural Sciences;2011-29
7 WANG Fu-yuan et al(Higher Vocational and technical School,China Pharmaceutical University,Nanjing,Jiangsu 211198);Study on the Preparation Technique on Synthetic Seeds of Atractylodes macrocephala Koidz.[J];Journal of Anhui Agricultural Sciences;2012-02
8 RAO Jun-feng et al(Hangzhou Vocational and Technical College,Hangzhou,Zhejiang 310018);High-quality and High-yield Cultivation Technique of Two Segments Method for Crocus sativus L.in Zhejiang Province[J];Journal of Anhui Agricultural Sciences;2012-09
9 WANG Jin-ming et al(Shanxi Zhendong Daodi Drugs Development Co.,Ltd.,Changzhi,Shanxi 047100);Resources Survey and Analysis of Wild Forsythia suspensa(Thunb.)Vahl[J];Journal of Anhui Agricultural Sciences;2012-15
10 HAO Cai-qin et al(Ningxia Polytechnic,Yinchuan,Ningxia 750002);Effects of Ethanol Concentration on the Extraction Rate of Gentiopicroside from the Gentiana macrophylla Pall in Ningxia Liupan Mountain of China[J];Journal of Anhui Agricultural Sciences;2012-18
China Proceedings of conference Full-text Database 9 Hits
1 Wan Yan Henan University of Traditional Chinese Medicine,Zhengzhou,Henan,China 450008;Determination of Astragaloside Ⅳ in astragalus by HPLC-ELSD[A];[C];2012
2 Qunying Mao~1,Zengbing Guo~2,Chunsheng Hao~3,Dan Yu~4,Xiuling Li~3,Zhenglun Liang~1;The study of the standard virus candidate strain for Enterovirus 71 neutralization antibOdy determination[A];[C];2011
3 CHEN Zan-min,CHEN Ying-jiang (Hainan Provincial Institute for Drug Control,Haikou 511002 China);Determination of Ethylenediamine in Aminophyline by Capillary Gas Chromatography[A];[C];2010
4 ZHANG Ai-wu,LIU Le-le,LUO Su-qin,et al. (Department of Pharmacy,Affiliated Hospital,Inner Mongolia Medical College,Hohhot 010050 China);DETERMINATION OF FERULIC ACID IN MALVAE FRUCTUS BY HPLC[A];[C];2010
5 Zhou Junhui Liu Guoyu Zhang Lei Wang Daqi (Xi'an Botanical Garden,Institute of Botany of Shaanxi Province,Xi'an,Shaanxi 710061);Purification Technology of Aesculin and Fraxin from Fraxinus stylosa Lingelsh.[A];[C];2011
6 ZHAO Meng~(1,2),WEI Shuo-nan~1,HU Zheng-hai~(1*) (1.College of Life Science,Northwest University,Xi'an 710069,China; 2.Shanxi Normal University,Linfen 041004,China);Pharmacognostical Studies on Dry Lacquer and Calined Dry Lacquer[A];[C];2010
7 Hengqiang Zhao~1,Yanling Geng~1,Jinpeng Yuan~1,Qinghua Cui~2,Xiao Wang~1,Jianhua Liu~1 (1.Shandong Analysis and Test Center,Shandong Academy of Sciences,Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province,Jinan 250014,China; 2.College of Pharmacy,Shandong University of Traditional Chinese Medicine,Jinan 250355,China);Determination of cAMP in fructus jujubae by UAE-HILIC-DAD-ESI-Q-TOF/MS[A];[C];2012
8 ZHANG Li,DUAN Jinao,DING Anwei (Jiangsu Key Laboratory for High Technology Research of TCM Formulae,Nanjing University of Chinese Medicine Nanjing 210046,China);The Subsequent Revision of Standard of Chinese Pharmacopoeia 2010 Edition VolumeⅠof Thinking by the Provisions of The Crude Drugs Standards of The Japanese Pharmacopoeia 16~(th) Edition[A];[C];2012
9 SHU Ya-chun~(1,3),QIN Kun-ming~2,CHEN Ya-jun~1,ZHU Xuan-xuan~1,CAI Hao~3,LU Tu-lin~3,LI Huan~3, CAI Bao-chang~(1,3) (1 Affliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China;2 Nanjing Haichang Group Corporation of Chinese Medicine,Nanjing 210061,China;3 Engineering Center of State Ministry of Education for Standardization of Chinese Medicine Processing,Nanjing University of Chinese Medicine,Nanjing 210029,China);Study on the different decocting methods on Yinqiao San decoction of anti-inflammatory and antipyretic effects[A];[C];2013
Chinese Journal Full-text Database 10 Hits
1 HU Yong-hong*, ZENG Ke-qin, ZHANG Ming-min, TU Sheng-hao, LAI Xian-yang, ZHANG Wei-Shen. *Institute of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China;Effects of triptolide on the expression and activity of nuclear factor κB in synovium of collagen-induced arthritis rats[J];Chinese Journal of Rheumatology;2004-09
2 GAO Dong,LIU Ru-yu,ZHANG Zhen-lin(Department of Integrative Medicine,FCTCM,Fuzhou,Fujian 350108,China);Experimental Study of Hepatoma Cells Apoptosis Induced by Lobelia Chinensis Lour.through Calcium Pathway[J];Journal of Fujian College of Traditional Chinese Medicine;2006-06
3 CHEN Mei-jun, LIANG Tong, ZHOU Ke-yuan (Department of Biochemistry, Guangdong Medical College, Zhanjiang 524023, China);Proanthocyanidins inhibited the LPS-induced DNA binding activity of nuclear factor of kappa B(NF-κB) in cells of RAW264.7 cell line[J];Journal of Guangdong Medical College;2005-02
4 CHEN Ri lai 1,WU Ting Jun 2,DAI Yue Jing 2 1 Meilin Hospital of Shenzhen City,Shenzhen 518049 China; 2.School of Pharmacy, West China University of Medical Sciences,Chengdu 610041 China;STUDIES ON THE CHEMICAL CONSTITUENTS OF FOUR SPECIES OF CHAENOMELES[J];WEST CHINA JOURNAL OF PHARMACEUTCAL SCIENCES;2000-01
5 JIANG Yan-yan,SHI Ren-bing,LIU Bin,WANG Qiu-ying,DAI Ying(School of Chinese Pharmacy,Beijing University of Chinese Medicine,Beijing 100102);Studies on chemical constituents of flavones from Lobelia chinensis Lour[J];Journal of Beijing University of Traditional Chinese Medicine;2009-01
6 WANG Jing-Jing~1,FAN Xiu-Zhen~2,LIU Shang-Ming~1,WEI Xin-Bing~1,REN Dong-Mei~3,CHEN Rong~1,LI Li~1,and HU Wei-Cheng~1(1.School of Medicine;2.School of Nursing;3.School of Pharmaceutical Sciences,Shandong University,Jinan 250012,China);Lobelia Chinensis Lour Alkaloids Inhibiting Rat Aortic Vascular Smooth Muscle Cell Proliferation Induced by Endothelin[J];Chinese Journal of Arteriosclerosis;2006-02
7 ZHANG Xiao-Ling1,XUE Bing1,LI Li1,CHEN Rong1,REN Dong-Mei2,LI Rui-Feng1,and HU Wei-Cheng1(1.School of Medicine;2.School of Pharmaceutical Sciences,Shandong University,Jinan 250012,China);Lobelia Chinensis Lour Alkaloids Inhibit Expression of Endothelin-1 mRNA and Protein in Renal Hypertensive Rats[J];Chinese Journal of Arteriosclerosis;2007-01
8 SHAO Jinhua,ZHANG Hong(Medicine Department of Intergrated Traditional Chinese and Western Medicine,the Second Affiliated Hospital of Dalian Medical University,Dalian 116023,China);Influence of lobelia chinensis lour decoction on expression of C-erbB-2 and P53 on H22 tumor-bearing mice[J];Chinese Journal of Clinical Pharmacy;2010-06
9 HU Yae**,MAO Jiahui,LIU Xia,SHI Haiyan,ZHU Yan,ZHOU Ailing***(Department of Pathophysiology,Medical School of Nantong University,Nantong 226001);Effect of oxymatrine on lipopolysaccharide-induced nitric oxide releasing and inducible nitric oxide synthase expression in RAW 264.7 cells[J];Journal of Nantong University(Medical Sciences);2011-03
10 HE Shan,WU Guo-xin(College of life sciences,Fujian Normal University,Fuzhou 350108,China);Extract of alkaloids from Lobelia chinensis Lour and their inhibitory effects on growth of Myeloma Cells U266[J];Strait Pharmaceutical Journal;2012-09
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 Yang Wei,Wang ShaoDepartment of Physiology);Coordinated analgesic effect of PrCl3 and alfalfa saponin[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;1995-06
2 Ma Xuemei, Mao Zijun(Northeast Forestry University , Harbin 150040, P. R. China);A Summary on the Exploitation and Utilization of Source Plant Ledum plasture L[J];Journal of Northeast Forestry University;2003-06
3 ZHANG Wei-min~1,ZHANG Yan-ming~1,ZHANG Tao~2,ZHANG De-gang~1,LIAO Xiao-min~1,ZHANG Yi-yun~1(1.College of Animal Science and Technology,Northwest A & F University,Yangling,Shaanxi,712100,China;2.Xi'an Animal Husbandy and Veterinary Institute,Xi'an,Shaanxi,710061,China);Studies on Antibacterial and Anti-inflammafory Effect of Alkaloid of Sophora alopecuraides L.[J];Progress In Veterinary Medicine;2005-10
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