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《China Pharmaceuticals》 2019-07
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Anti-Inflammatory Pharmacodynamics of Jinshu Capsules

LIU Yusong;GUO Liang;LIU Caiying;LI Lan;MA Shanzhi;LI Qing;YE Chengli;WEN Qiao;GUO Jianhua;Chongqing Orthopaedic Hospital of Traditional Chinese Medicine;Chongqing Academy of Chinese Materia Medica;  
Objective To investigate the anti-inflammatory effect of Jinshu Capsules on chronic soft tissue injury.Methods The anti-inflammatory effect of Jinshu Capsules was observed by using the xylene-induced ear swelling model in mice, cotton ball granuloma model in rats and chronic soft tissue injury model in rats.Results The high and middle dosage groups of Jinshu Capsules(20.8,10.4 g crude drugs per kilogram of body weight) had obvious inhibitory effect on xylene-induced ear swelling in mice.The high and middle dosage groups of Jinshu Capsules(10.4,5.2 g crude drugs per kilogram of body weight) had obvious inhibitory effect on cotton ball granuloma, and had obvious improvement and repair effect on soft tissue injury in model rats.Conclusion Jinshu Capsules have an obvious anti-inflammatory effect on chronic soft tissue injury.
【Fund】: 2016年重庆市卫生计生委中医药科技项目[zy201602033]
【CateGory Index】: R285.5
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