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《Practical Journal of Clinical Medicine》 2006-02
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Clinical evaluation for protein chip system of multi-tumor marker detection

FU Ben-qi,LIU Xian-hua,SHE Wei,et al.(Nuclear Medicine Department,Sichuan Provincial People's Hospital,Chengdu 610072,China)  
Objective To study the clinical value of protein chip system in the detection of multi-tumor markers(C-12 system).Methods The serums of 114 malignant tumour patients,32 benign disease patients and 52 healthy subjects were detected by C-12 system.The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of C-12 system were analyzed.The results of C-12 system were compared with those of chemiluminescence immunoassay,DELFIA and IRMA,and the correlation between C-12 system and the others was evaluated.Results Among the 114 malignant tumour patients,106 were positive,while 19 were positive among 84 controls.The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of C-12 system were 92.9%,77.4%,86.4%,84.8%,89.0%,respectively.There was significant positive correlation between the results of C-12 system and the others(r=0.494~0.895,P 0.001).Conclusion C-12 system is appropriate for clinical diagnosis and outcome prediction of tumours,particularly for tumour screening of healthy group.
【CateGory Index】: R730.4
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【References】
Chinese Journal Full-text Database 2 Hits
1 SUN Xin BAO Yangyi BAO Jian The First Affiliated Hospital of Anhui Medical University,Hefei 230022,China;The significance of detecting serum tumor markers and cytokines for patients with breast cancer[J];China Medicine and Pharmacy;2011-13
2 ZHANG Ming-zhou~(1,*),LIU Jun~1,HU Hua-jun~1,SU Zhi-chun~2,YU Xiao-ping(~1College of Life Sciences,China Jiliang University,Hangzhou 310018,China;~2Wenzhou Meizhong Medical Laboratory Center,Wenzhou 325007,China);Preparation and evaluation of protein chip diagnosing hepatitis B and hepatic cancer[J];Acta Agriculturae Zhejiangensis;2006-05
【Citations】
Chinese Journal Full-text Database 3 Hits
1 LAN Xiao-peng, ZHAO meng, MA Li-qiang, XUE Zhao-qing (Center of Medical Laboratory Science, Fuzhou General Hospital,Fuzhou 350025, Fujian ,China);Clinical application of a micro-array for multi-tumor marker detection[J];Journal of Medical Postgraduates;2004-08
2 JIA Hai-Wei, ZHANG Wei-Jing (Affiliated Hospital,Academy of Military Medical Sciences,Beijing 100039,China);Protein chip technology and its application to the research on tumor[J];Bulletin of The Academy of Military(Medical Sciences);2004-01
3 Ming Desong,Huang Qingliu,Huang Yingying Department of Laboratory Medicine, the First Hospitol, Quanzhou 362000;EVALUATE THE CLINICAL VALUE OF PROTEIN CHIP SYSTEM(C_(12)) FOR DETECTING MULTI-MARKER OF TUMOR[J];China Journal of Modern Medicine;2003-17
【Co-citations】
Chinese Journal Full-text Database 5 Hits
1 Xiao Chuangqing, Jiang Li, Zhou Guanghua, et al. Departmant of Laboratory Medicine, 163rd Hospital of PLA, ChangSha (410003);Clinical Values of Detection of Multiple Tumor Markers in Pleural Fluid for Diagnosis Malignancy[J];Journal of Radioimmunology;2005-02
2 ZHANG Ke~1,FAN Zhong-yuan~1,LEI Xun~2,et al. (1.Department of Clinical Laboratory,Sichuan Cancer Hospital,Chengdu 610041,China);Evaluation of Multi-tumor Markers Protein Chip Diagnostic System in the Diagnosis of Pancreatic Cancer[J];West China Medical Journal;2006-01
3 ZHOU Xiu,ZHANG Ai-min,JIN Ying,WANG Shi-yu,ZHANG Gui-fen(Department of Clinical Laboratory,The Affiliated Hospital of Medical College of Chinese People's Armed Police Force,Tianjin 300162,China);The diagnositic value of testing tumor protein chip in primary liver cancer[J];Acta Academiae Medicinae CPAF;2008-11
4 Wang Yufang,Li Shouqing,Yang Guangmin,et al.Central Hospital of Changchun,Changchun 130051;Value analysis of combined measurement of multi-tumor markers in malignant tumor diagnosis[J];Modern Medicine Journal of China;2009-03
5 SI Xue-zhong,GAO Yong,LIU Zhi-zhong(Department of Clinic Laboratory,Beijing Tiantan Hospital,Capital Medical University,Beijing 100050,China);Analysis of multiple tumor markers in patient with pulmonary infection[J];Chinese Journal of Health Laboratory Technology;2010-08
【Co-references】
Chinese Journal Full-text Database 6 Hits
1 LIU Yong, LI Fu-quan, WANG Jia-jia, et al. (No.455 Army Hospital, Shanghai 200031, China);Protein Biochip Technology Detecting Multi-tumor Markers and Their Clinical Application Values in Three Kinds of Carcinomas[J];Labeled Immunoassays and Clinical Medicine;2005-02
2 DING Bo-ni, CHEN Dao-jin, WU Jun-hui, et al. Department of General Surgery, The Third Xiangya Hospital, Central South University, Changsha 410013,China;Expression and Significance of CA125 and CA15-3 in Human Breast Cancer[J];Journal of Chinese Physician;2005-01
3 Zhang Jinchi, Chen Linxing, Yao Yingfei, et al.Department of Laboratory, The 2 nd Affiliated Hospital, Medical College of Shantou University, Shanotou (515041);Diagnostic Value of Combined Detection of Serum CA15-3, CEA, SFContents in Patients with Breast Cancer[J];Journal of Radioimmunology;2005-01
4 CHEN Jun,GUO Guangyun,XU Shaoyong,et al.Department of Gastroenterology,Renmin Hospital,Yunyang Medical College,Shiyan 442000,China;Application of multi-tumor markers protein chip diagnosis system in the Pancreatic cancer[J];Journal of Clinical Internal Medicine;2004-05
5 YUAN Yu-ning,XONG Shu-ming. Affiliated Hospital of Guangdong Medical College,Zhanjiang,524001;Affiliated Ruijing Hospital of Shanghai second Medical University,Shanghai,200025;The Determination and Significance of Serum IL-6 and TNF-α Levels in Multiple Myeloma Patients[J];THE PRACTICAL JOURNAL OF CANCER;2000-03
6 WANG Shaobin , RUI Jingan, LIU Yuhuei,et al. Liver Cancer Institute,Post and Telecommunication General Hospital,Beijing 100032,China;The detection of α-fetoprotein mRNA in peripheral blood of patients with hepatic carcinoma and its clinical significance[J];CHINESE JOURNAL OF GENERAL SURGERY;2000-01
【Secondary Citations】
Chinese Journal Full-text Database 7 Hits
1 ZHAO Jizong;WU Boheng(The First Affiliated Hospital of Sun Yat-sen University of Medical sciences,Guangzhou 510080);THE CLINICAL PRACTICAL STUDY OF ATUMOR RELATED ANTIOEN(CA_(19-9))OF DIGESTIVE TRACT[J];CHINESE JOURNAL OF CANCER;1996-02
2 ZHANG Zhi qin.No.6 Hospital of Xuzhou,Xuzhou 221006,P.R.China;The Value of SF,AFP,CEA and β_2-M in Diagnosis of Malignant Tumors[J];Journal of Qilu Oncology;2001-02
3 Tang Bu-jian; Li Li;Xu Jin; et al. (Affiliated Tumor Hospital of GuangxiMedical University, Nanning, 530027).;The diagnostic value of the assay of lactatedehydrogenese combined with other tumormarkers in ovarian cancer[J];Chinese Journal of Obstetrics And Gynecology;1994-06
4 QI Jun,CHE Yi-qun. Department of Lab Med, Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021,China;Application of multi-tumor markers protein chip diagnose system in the diagnosing of ovarian cancer[J];Chinese Journal of Laboratory Medicine;2003-06
5 LI Xiao liang,SUN Da chun. Zhuhai People's Hospital(Zhuhai,519000);CLINICAL OBSERVATION OF MALIGNANT TUMOR DIAGNOSIS AND DETECTION VIA SERUM TUMOR MARKER[J];Cancer Research and Clinic;2002-03
6 Xie Hanhua Department of Breathing,Hainan People's Hospital,Hainan 570311;TUMOR MARKER CA_(125) 、 CA_(153) 、 CA_(199) AND CEA IN LUNG CANCER[J];China Journal of Modern Medicine;2001-01
7 Gao Hui, Lin Gang, Liu Tonglin,et al. Department of Thoracic Surgery,Peking university First Medical School (100034);MEASUEMENT OF SERUM CYFRA21-1、NSE、CEA IN DETECTING LUNG CANCER[J];China Journal of Modern Medicine;2001-11
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