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《Evaluation and Analysis of Drug-Use in Hospitals of China》 2012-04
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Pharmacoeconomic Analysis on Tamoxifen vs.Toremifene for Treatment of Breast Cancer

LIN Yan*,TAO Hong-hui#,YAN Chu-shun,WENG Le-jin,DAI Jia-lin(Dept.of Pharmacy,Shanghai Huangpu District Central Hospital,Shanghai 200002,China)  
OBJECTIVE:To evaluate the pharmacoeconomic value of tamoxifen versus toremifene as endocrine therapy for breast cancer.METHODS: 130 patients with breast cancer were assigned to receive either tamoxifen(group TAM,n=80 cases) or toremifene(group TOR,n=50 cases).The curative efficacy and safety of two therapies were recorded and evaluated using cost-effectiveness analysis in pharmacoeconomics.RESULTS: In TAM group versus TOR group,the drug cost stood at 90.30 yuan vs.809.52 yuan,with effective rate of 88.75% vs.94%.CONCLUSION: TAM is superior to TOR in terms of pharmacoeconomics.
【Fund】: 上海市黄浦区卫生局科研项目(编号:2008-HGG-19)
【CateGory Index】: R737.9
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