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Yang Yuexin,Liu Jianyu,Cui Hongmei (Chinese Academy of Preventive Medicine,Institute of Nutrition and Food Hygiene, Beijing 100050)  
Zinc absorption speed and bioavailability were studied by four zinc compounds(zinc sulfate,zinc glycinate,zinc lactate and zinc gluconate) on two animal experiments:in one study the process of zinc digestion and absorption was observed in rats during 0-720 min after ingestion of zinc on 6.0mg/kg bw rats.In another experiment zinc storage in tissue of rats fed lower zinc diet (7.6mg/kg diet)with different zinc level water (0,15,30,60mg/kg water w/w) was studied. The findings were as follows: 1.Rats were killed by different time (0,5,15,30,60,120,240,480,720min)after zinc fed was at 6.0mg/kg bw,serum and tissue zinc contents were analyzed.The absorption speed of zinc glycinate was faster than others when rats had same amount zinc intake,the highest content in serum was 100μmol/L at the time of 15 min,the highest level of zinc lactate and gluconate was 66.0 and 79.5μmol/L at 30 min respectively,zinc sulfate was 78.9μmol/L at 60 min. 2.Zinc contents of serum,liver,intestine and kidney were determined.There were higher absorption when zinc glycinate was at the level of 15mg/kg water,zinc lactate and gluconate were at 30 mg/kg water,the zinc content of serum and tissues in sulfate group depended on zinc sulfate level in water. 3.Bioavailability of different zinc compounds was calculated by using 3p87 model,suppose that zinc sulfate as 100%,zinc glycinate,zinc lactate and gluconate was 124%,73% and 132% respectively.
【Key Words】: zinc compounds absorption speed bioavailability
【Fund】: 北京自然科学基金
【CateGory Index】: R151.3
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