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《Yunnan Journal of Traditional Chinese Medicine and Materia Medica》 2006-06
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Influence of the Total Flavonoid of Stalk and Leaves of Panax Notoginseng on SMMC-7721 Cell Proliferation

ZHANG Zhi-xin,HUANG Bao-gui,ZHANG Shi-xiu,SONG Guan-bin(Wenshan Higher Teacher Training School,Yunnan,663000)  
Objective: To observe the influence of the total flavonoid of stalk and leaves of panax notoginseng on SMMC-7721 cell proliferation and withering.Methods: MTT method was used to examine and test the inhibiting effect of the total flavonoid of stalk and leaves of notoginseng with different density on SMMC-7721 cell proliferation and a flow cytometry was used to analyze the cell withering.Results: The total flavonoid of stalk and leaves of notoginseng with different density turned to be 24h,48h,72h respectively.The total flavonoid of stalk and leaves of notoginseng showed the inhibiting effect on the SMMC-7721 cell proliferation of human liver cancer cells,and its dependence on time and dosage.Conclusion: The total flavonoid of stalk and leaves of panax notoginseng has changed the periodic distribution of SMMC-772,i.e.the fall of G1 periodic cell percetntage and the rise of S periodic percentage,which presents dosage dependence.
【Fund】: 云南省教育厅科学研究基金项目(编号:5Z0505C)
【CateGory Index】: R285.5
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