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《Chinese Journal of Oncology Prevention and Treatment》 2012-04
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In vitro antitumor effects of total flavonoids from Camellia Chrysantha(Hu) Tuyama

NONG Cai-li,CHEN Yong-xin,HE Xian-ke,WEI Jin-bin△(△Pharmaceutical College of Guangxi Medical University;Graduate School of Guangxi Medical University,Nanning 530021,P.R.China)  
Objective To observe the inhibitory effects of total flavonoids from Camellia Chrysantha(Hu) Tuyama on four malignant tumor cell lines in vitro.Methods Malignant tumor cell lines SMMC-7721,CNE-1,SGC-7901 and H460 were treated with total flavonoids,and inhibition of cell proliferation was measured using the MTT assay.Results Total flavonoids from Camellia Chrysantha(Hu) Tuyama were found to exert antiproliferative activity on all four tumor cell lines in a dose-dependent manner.IC50 values(μg/ml) were 242.44 for SMMC-7721 cells,313.79 for CNE-1,259.87 for SGC-7901 and 385.87 for H460.Conclusion Total flavonoids from Camellia Chrysantha(Hu) Tuyama can inhibit cell proliferation of SMMC-7721,CNE-1,SGC-7901 and H460 in vitro.
【Fund】: 广西壮族自治区卫生厅中医药科技专项课题(GZKZ10-102);; 广西科技基础条件平台建设项目(10-108-19);; 广西医科大学博士启动基金资助课题(02305207004)
【CateGory Index】: S685.14
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