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《The Chinese Journal of Dermatovenereology》 2015-10
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Detection of Serum Ferritin and Squamous Cell Carcinoma Antigen in Hospitalized Patients

MA Cui-cui;LIU Yan;YIN Jia-feng;YANG Sheng-lian;ZHAO Bo;The Second Affiliated Hospital of Xi'an Jiaotong University,College of Medicine;  
Objective To examine the serum FET and SCCA levels of patients with skin diseases and their clinical significance. Methods The serum FET and SCCA levels of 514 cases of hospitalized patients in our department and 514 cases of eligible patients of other departments were detected and analyzed. Results The number and percentage of patients with skin diseases who had higher serum FET and SCCA levels were 129( 25. 10%) and 257( 50. 00%),respectively,significantly higher than those of the control group. The serum FET levels of connective tissue disorders also increased. The serum SCCA levels of psoriasis( 92 /96),eczema( 21 /22),erythrodermia( 24 /26),generalized neurodermatitis( 6 /7),hypereosinophilic dermatopathy( 7 /9),pityriasis rubra pilaris( 3 /4) increased significantly. The serum FET and SCCA levels of skin cancer had no obvious change. Conclusion The serum FET levels of connective tissue disorders might rise. Squamous cell hyperplasia accompanied by a large scaly skin disease had higher serum SCCA level,especially in the erythroderma,psoriasis,hypereosinophilic dermatopathy,and dermatitis. The higher serum FET and SCCA levels were not a common skin cancer specific indicator( except for SCC).
【Fund】: 西安交大院科技骨干项目(RC(GG)201204) 多发性家族性毛发上皮瘤基因突变及临床研究
【CateGory Index】: R751
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