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《Chinese Journal of Pathophysiology》 2008-04
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Effects of Sini decoction against pulmonary injury induced by ex vivo ischemia-reperfusion in rats

LIU Xiao-ai1, LIU Guo-hui1, CHEN Yan-fei2, LI Jian-hua1, HU Jing-xin1(1Department of Physiology, 2Department of Clinic, Guangzhou Medical College, Guangzhou 510182, China. )  
AIM:To observe the effects of Sini decoction against pulmonary injury induced by ex vivo ischemia-reperfusion in rats. METHODS: The model of ischemia-reperfusion was established. Twenty-four Sprague-Dawley rats were randomly divided into Sham, I/R, and SND groups. Wet to dry lung weight ratio (W/D), mean pulmonary artery pressure (MPAP), SOD activity and MDA contents in pulmonary perfusate and tissue, NOS activity and NO contents in pulmonary tissue were detected. The pathologic changes in pulmonary tissue were also observed by light microscope. RESULTS: The morphological changes of pulmonary injury were alleviated in SND group. Wet/dry ratio, MPAP and MDA contents in pulmonary perfusate and tissue were significantly lower in SND group after ischemic/reperfusion. SOD activity in pulmonary perfusate and tissue, and NO contents in pulmonary tissue were significantly higher in SND group than those in I/R group. No significant difference in NOS activity in pulmonary tissue among three groups was observed. CONCLUSION: These results indicate that SND may have a protective effect on ischemia-reperfusion injured lung by its antioxidant activity and by adjusting NO level.
【CateGory Index】: R285
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8 LU De-qin,LI Tao,CHEN Ying,et al.Department of Pathophysiology,Guiyang Medical College,Guizhou 550004,China;Protective effects of opener of mitochondrial ATP sensitive potassium channel against ischemia-reperfusion injury in rat lung[J];中国急救医学;2010-03
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5 LIU Ke-xuan 1,2, WU Wei-kang2, LUO Han-chuan2, ZHAO Ming-qi2, ZHAO Dan-yang2 ( 1 The First Affiliated Hospital, 2Institute of Integrative traditional Chinese and Western Medicine, SUN Yat-sen University, Guangzhou 510080, China);Effects of Sini decoction on the ultrastructure of small intestinal epithelial cells in rats with intestinal ischemia-reperfusion[J];中国病理生理杂志;2004-04
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4 LU Xiaoling;YOU Haoyuan;HUANG Cuilan;LIU Chengyuan;Department of Surgery,Yushui District Maternal and Child Care Service Centre of Xinyu City in Jiangxi Province;Department of Trauma Emergency, the First Hospital Affiliated to Nanchang University;;Effects of acute alcoholism on blood gas analysis in rabbits[J];中国现代医生;2014-35
5 YOU Hao-yuan;HUANG Cui-lan;LIU Cheng-yuan;LU Xiao-ling;HUANG Liang;Department of Emergency,the First Affiliated Hospital of Nanchang University;Department of General Surgey,Maternal and Child Health Hospital of Yushui District of Xinyu;;Effect of Acute Alcohol Poisoning on Inflammatory Mediators in Rabbits with Hemorrhagic Shock[J];南昌大学学报(医学版);2014-11
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7 WANG Xiao-li;DONG Miao-xian;XU Tian-jiao;LI Cheng-chong;SUN Ji-kai;LI Xiao-ming;Qiqihar Medical College;Changchun University of Chinese Medicine;;Protective effect of β-asarone on primary rat hippcampal neurons against hypoxia/hypoglycemia and reperfusion injury[J];中国病理生理杂志;2014-05
8 Wang Di;Liu Hongbai;Heilongjiang River Fisheries Research Institute/Chinese Academy of Fisheries Sciences;;Effects of Prescription A on Anti-oxidation Capability in Amur sturgeon (Acipenser schrencki Brandt.)[J];中国农学通报;2013-32
9 LI Shao-wu,WANG Di,LU Tong-yan,LIU Hong-bai(Heilongjiang River Fisheries Research Institute,Chinese Academy of Fishery Sciences,Harbin 150070,China);Effects of Three Chinese Medicinal Herb Complex Additives on Antioxidation in Amur Sturgeon(Acipenser schrencki Brandt)[J];水产学杂志;2012-03
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9 ZHANG Hong-xia,WU Yong-jie,GAO Ming-tang Department of Pharmacology,School of Basic Medical Science of Lanzhou University,Key Laboratory of Preclinical Study of New Drugs of Gansu Province,Lanzhou 730000,Gansu,China;Protective effects of DDPH on myocardial ischemia reperfusion injury in isolated rat hearts[J];中国临床药理学与治疗学;2010-02
10 XU Chang-qing,ZHANG Wei-hua(Department of Pathophysiology,Harbin Medical University,Bio-pharmaceutical Key Laboratory of Heilongjiang Province,Harbin 150086,China. );Investigation progress of CaSR in cardiovascular system[J];中国病理生理杂志;2010-02
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 Wang Xiujuan;Zhong Xiaopeng;Ding Bo;Zhang Shiwu;Department of Emergency, Tianjin People's Hospital;;An experimental study on brain protective effect of Sini decoction on post-resuscitation syndrome[J];中国中西医结合急救杂志;2017-04
2 WANG Jing;WANG Hai-hua;ZHOU Ping-ping;JIANG Yu-xin;Department of Physiology,Wannan Medical College;;Regulation Mechanism of Ginkgo-Dipyridamolum for Calcium Homeostasis on Cardioprotective Effect During Ischemia Reperfusion Injury[J];中药材;2015-12
3 ZHAO Jianwen;WANG Zhiyong;YAN Guoqiang;ZHANG Yanwei;XIE Xinling;SONG Shuchang;Hebei Province Cangzhou Chinese and Western Medicine Hospital;;Experimental Research Progress of TCM on Vascular Dementia[J];辽宁中医药大学学报;2015-11
4 WANG Chun;LIU Li-mei;SONG Zhi-qian;DONG Yun-zhuo;DU Zhi-yong;NING Zhang-chi;LIU Yuan-yan;LIU Zhen-li;The Institute of Basic Theory,China Academy of Chinese Medical Sciences;School of Chinese Pharmacy,Beijing University of Chinese Medicine;;Survey of active components in commonly-used Chinese materia medica injections and related Chinese materia medica for cardiovascular disease[J];中草药;2015-15
5 ZHAO Lan-ping;XUE Shu-fang;CHEN Yan-jing;WANG Xue-fang;CHEN Li-feng;Department of Physiological,Hebei North University;Institute of Basic Theories,China Academy of Chinese Medical Sciences;;Effects of nitric oxide on spontaneous action potentials of guinea-pig left ventricular outflow tract under the conditions of ischemia/reperfusion[J];中国病理生理杂志;2015-07
6 RONG Xueying;GUO Hongmin;HUANG Xuxia;Nanjing University of TCM;;Treatment of SIRS by Chinese herbal compound[J];长春中医药大学学报;2015-01
7 LI Zhi-hui;YANG Chang-chun;HAN Ying;The First Department of South Building,the General Hospital of Chinese People's Armed Police Forces;Xinxiang Medical College;;Research Progress of Adiponectin and Vascular Endothelial Function Repair[J];医学综述;2014-10
8 Cai Mengmeng;Bao Hongguang;Si Yanna;Xu Li;Han Liu;Shi Tao;Wang Hongyu;Xie Xinyi;Department of Anesthesiology,Nanjing Hospital Affiliated to Nanjing Medical University(Nanjing First Hospital);;Effects of adiponectin pretreatment on CD11b expression and respiratory burst activity of peripheral blood polymorphonuclear leucocytes in septic rats[J];中华麻醉学杂志;2014-01
9 WANG Jing;JIANG Yu-xin;CUI Feng-juan;MIN Zhi-xue;ZHOU Ping-ping;WANG Hai-hua;Department of Physiology,Wannan Medical College;;Inhibitory effect of ginkgo-dipyridamole injection on ischemia/reperfusion injury in rat hearts in vitro[J];中国病理生理杂志;2013-09
10 Shi Yinglu,Ge Shenglin,Zhang Chengxin(Dept of Cardiovascular Surgery,The First Affiliated Hospital of Anhui Medical University,Hefei 230022);The protective role of nicorandil postconditioning in lung ischemia/reperfusion injury of rats[J];安徽医科大学学报;2013-07
【Secondary Citations】
Chinese Journal Full-text Database 9 Hits
1 LIU Yan 1, WU Wei-kang 2, YANG Cheng-ti 1, ZHAO Ming-qi 2, LUO Han-chuan 2 (? 1?Department of Cardiovascular of the Second Affiliated Hospital, Lanzhou Medical College, Lanzhou 730000,China; ? 2?Institute of Integrated Traditional Chinese and Western Medicine, Sun Yat-sen University of Medical Sciences, Guangzhou 510080, China);Liver protection by Sini decoction in hemorrhagic shock and its mechanism relating to oxygen free radical and nitric oxide[J];中国病理生理杂志;2003-06
2 HEI Zi-qing 1,2 , WU Wei-kang 1, SUN Hui-lan 1, HUANG He-qing 1, TAN Hong-mei 1, LUO Han-chuan 1 (? 1?Institute of Integrated Traditional Chinese and Western Medicine, Sun Yat-sen College of Medical Sciences,? 2?The First Affiliated Hospital of Zhongshan University, Guangzhou 510089, China);Effects of Sini decoction on atherosclerosis and ceramide content of aorta in rabbits[J];中国病理生理杂志;2003-03
3 SU Pixiong *, GUAN Yingpeng, YOU Bin, et al. * Heart Center, Beijing Chaoyang Hospital,Beijing 100020;Stereological studies of myocardium in different types of rheumatic vavular diseases[J];中华胸心血管外科杂志;2000-06
4 LHO Han-Chuan, HUANG He-Qing, LIU Xiao-Xia, CHEN Jian-Ping, TAN Hong-Mei, YANG Hui, TANG Tie-Jun, LIANG Tian-Wen,WU Wei-Kang Department of Pathophysiology, Sun Yat-sen University of Medical Sciences, Guangzhou (510089);Experimental research on the protective effect of SiNi decoction on acute ischemic myocardium[J];中国病理生理杂志;1999-11
5 Huang Luosheng; Zhao Weichun; Xia Yufeng(School of Traditional chinese Medicines, Nanjing 210038;Institute of Drug Inspection,Tianjing 300070);Effect of Preparation Methods on the Content of Alkaloids and Glycyrrhetic Acid in Sini Injection[J];中国药科大学学报;1999-05
6 JIANG Lan, ZHAO Xiu-Mei, TIAN Niu, LIU Yu-Ying, LI Xiang-Hong, JIANG Chao-Guang Lab of Microcirculation, Chinese PLA General Hospital, No. 28 Fuxing Road, Beijing (100853);Simulation study of hemodynamic of small intestinal villosity microvessels in vitro[J];中国病理生理杂志;1999-01
7 WU Wei-Kang,HOU Can,LUO Han-Chuan,CHENG Chao,TAN Hong-Mei Department of Pathophysiology,Sun Yat-sen University of Medical Sciences,Guangzhou(510089);Effects of Sini Decoction improving energy metabolism of ischemic myocardium and mechanisms of the effects[J];中国病理生理杂志;1998-06
8 Wu Wei-kang Yang Kun Wu Jin-lang Dept.of Pathophysiology,Sun Yat-sen University of Medical Sciences,Guangzhou(510089);Uitrastructural Observation of Protective Effects of Sini Decoction(四逆汤)on Ischemic Myocardium[J];中国中西医结合杂志;1995-S1
9 Wu Weikang;Luo Hanchuan and Hou Can(Sun Yatsen University of Medical Sciences,Guangzhou 510089);In Vitro Experiment on Scavenging Oxy-radical and SuppressingMyocardial Lipid Peroxidation with Sini Decoction[J];中国中药杂志;1995-11
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