Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Pathophysiology》 2008-04
Add to Favorite Get Latest Update

Effects of Sini decoction against pulmonary injury induced by ex vivo ischemia-reperfusion in rats

LIU Xiao-ai1, LIU Guo-hui1, CHEN Yan-fei2, LI Jian-hua1, HU Jing-xin1(1Department of Physiology, 2Department of Clinic, Guangzhou Medical College, Guangzhou 510182, China. )  
AIM:To observe the effects of Sini decoction against pulmonary injury induced by ex vivo ischemia-reperfusion in rats. METHODS: The model of ischemia-reperfusion was established. Twenty-four Sprague-Dawley rats were randomly divided into Sham, I/R, and SND groups. Wet to dry lung weight ratio (W/D), mean pulmonary artery pressure (MPAP), SOD activity and MDA contents in pulmonary perfusate and tissue, NOS activity and NO contents in pulmonary tissue were detected. The pathologic changes in pulmonary tissue were also observed by light microscope. RESULTS: The morphological changes of pulmonary injury were alleviated in SND group. Wet/dry ratio, MPAP and MDA contents in pulmonary perfusate and tissue were significantly lower in SND group after ischemic/reperfusion. SOD activity in pulmonary perfusate and tissue, and NO contents in pulmonary tissue were significantly higher in SND group than those in I/R group. No significant difference in NOS activity in pulmonary tissue among three groups was observed. CONCLUSION: These results indicate that SND may have a protective effect on ischemia-reperfusion injured lung by its antioxidant activity and by adjusting NO level.
【CateGory Index】: R285
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 8 Hits
1 Liang Li;Jun-shan Yang;Wen-han Lin;Sheng-yuan Xiao;Hong-xia Liu;Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College;Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College;The State Key Laboratory of Natural and Biomimetic Drug, Peking University;School of Life Science,Beijing Institute of Technology;;Analysis on Chemical Constituents of Chinese Materia Medica Formulation Sini Decoction by HPLC-DAD-MS/MS[J];Chinese Herbal Medicines;2015-01
2 GAO Qi;HUANG Wendong;SU Meiling;YANG Yongfei;ZENG Zhi;ZHU Banghao;Cardiac and Cerebral Vascular Center, Zhongshan School of Medicine, Sun Yat-Sen University;;Protective effects of DLXSS on ischemia/reperfusion injury in isolated rat hearts[J];临床与病理杂志;2014-06
3 WANG Jing;JIANG Yu-xin;CUI Feng-juan;MIN Zhi-xue;ZHOU Ping-ping;WANG Hai-hua;Department of Physiology,Wannan Medical College;;Inhibitory effect of ginkgo-dipyridamole injection on ischemia/reperfusion injury in rat hearts in vitro[J];中国病理生理杂志;2013-09
4 LI Jian-hua1,JI Shuang-quan2,CHEN Fu-quan2,PENG Miao-ru2, LIU Xiao-ai2,ZHAO Shen-ting2,GAO Tian-ming1*(1.Neurobiology Department,Nanfang Medical University,Guangzhou 510515,China; 2.Physiology Department,Guangzhou Medical College,Guangzhou 510182,China);Effect of Sini Decoction on Learning and Memory Ability in Rats with Vascular Dementia[J];中国实验方剂学杂志;2011-12
5 ZENG Ping,YANG Yi-yu,WU Wei-kang,LIU Xiao-ai,TANG Juan,LIANG Yu-feng,WU Zhi-yuan,ZHU Nan-fang,LI Qiang-hua,LIAO Xiang-yi,ZENG Qi-yi;The early intervention of Sini decoction in SIRS rats[J];中国病理生理杂志;2009-06
6 QI Ren-bin,XIONG Yi,LU Da-xiang,WANG Yan-ping,FU Yong-mei(Department of Pathophysiology,Medical College of Jinan University,Guangzhou 510632,China.);Protection of Glycyl-L-Glutamine against myocardial ischemia-reperfusion injury in the isolated rat heart[J];中国病理生理杂志;2009-05
7 LIAO Wen-qiang1,PANG Yan2,ZHANG Yi-guan2,LI Xiao-hui2(1National Integrative Medicine Centre for Cardiovascular Diseases,China-Japan Friendship Hospital,Beijing 100029,China; 2College of Pharmacy,Third Military Medical University,Chongqing 400038,China.;Adiponectin protects human umbilical vein endothelial cells from lipid peroxidation[J];中国病理生理杂志;2009-03
8 LU De-qin,LI Tao,CHEN Ying,et al.Department of Pathophysiology,Guiyang Medical College,Guizhou 550004,China;Protective effects of opener of mitochondrial ATP sensitive potassium channel against ischemia-reperfusion injury in rat lung[J];中国急救医学;2010-03
【Citations】
Chinese Journal Full-text Database 6 Hits
1 ZHOU Xiao-hong, WEI Peng, LING Yi-qun, DAI Hong-yan, HUANG Xin-li, LING Yi-ling (Department of Pathophysiology, Hebei Medical University, Shijiazhuang 050017, China);Effect of endogenous H_2S on pulmonary hypertension during acute lung injury induced by LPS and its interaction with NO[J];中国病理生理杂志;2006-04
2 SUN Hui-lan,WU Wei-kang,LUO Han-chuan,LIANG Tian-wen(Institute of Integrated Traditional Chinese and Western Medicine,Sun Yat-sen University,Guangzhou 510080,China);Anti-myocardial ischemia-reperfusion injury of Sini Decoction's active fraction[J];中草药;2006-01
3 WANG Ting,JIANG Hao,XUE Zhang-gang,OU Zhou-luo△(Department of Anesthesiology,Zhongshan Hospital,△Department of Biochemistryand Molecular Biology,Shanghai Medical College,Fudan University,Shanghai 200032,China);Effects of Isoflurane Administration before Ischemia on Expression of Neutrophil Chemoattractant and the DNA Binding Activity of Nuclear Factor-κB in Lung Ischemia-Reperfusion Injury in Rats[J];复旦学报(医学版);2005-04
4 YAN Jian-yun1, WU Wei-kang2, LU Li-he2, LUO Han-chuan2 (1Department of Physiology, Guangzhou Medical College, Guangzhou 51 0182, China;?2?Department of Pathophysiology, Zhong Shan Medical School, S un Yat-sen University, Guangzhou 510080, China);Effect of sini decoction on the expression of bax and bcl-2 a fter focal cerebral ischemia in rats[J];中国病理生理杂志;2005-04
5 LIU Ke-xuan 1,2, WU Wei-kang2, LUO Han-chuan2, ZHAO Ming-qi2, ZHAO Dan-yang2 ( 1 The First Affiliated Hospital, 2Institute of Integrative traditional Chinese and Western Medicine, SUN Yat-sen University, Guangzhou 510080, China);Effects of Sini decoction on the ultrastructure of small intestinal epithelial cells in rats with intestinal ischemia-reperfusion[J];中国病理生理杂志;2004-04
6 LIU Yan 1, WU Wei-kang 2, YANG Cheng-ti 1, ZHAO Ming-qi 2, LUO Han-chuan 2 (? 1?Department of Cardiovascular of the Second Affiliated Hospital, Lanzhou Medical College, Lanzhou 730000,China; ? 2?Institute of Integrated Traditional Chinese and Western Medicine, Sun Yat-sen University of Medical Sciences, Guangzhou 510080, China);Liver protection by Sini decoction in hemorrhagic shock and its mechanism relating to oxygen free radical and nitric oxide[J];中国病理生理杂志;2003-06
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 YANG Yang;CHEN Dongfeng;Department of Gastroenterology,Institute of Surgery Research,Daping Hospital,Third Military Medical University;;Advance of mid-gut mucosal barrier: from basic to clinical study[J];胃肠病学和肝病学杂志;2015-11
2 YANG Xiao;ZHANG Shu-feng;WAN Hui-jie;Hebei Key Laboratory of Research and Exploitation of Traditional Chinese Medicine/Institute of Chinese Materia Media,Chengde Medical College;;INFLUENCES OF RHUBARB WATER EXTRACT ON EXPRESSION OF BCL-2 AND BAX IN UTERUS OF YOUNG FEMALE RATS WITH DIFFERENT DECOCTING TIME[J];承德医学院学报;2015-05
3 QIN Li;GUAN Li;LIN Rui-shan;XUE Qian-qian;XU Jin-wen;YAN Fu-man;LI Xiao-ying;LIU Hai-mei;Department of Physiology,Basic Medical College,Guangzhou University of Chinese Medicine;Western Medicine Basis Public Laboratory,Basic Medical College,Guangzhou University of Chinese Medicine;;Resveratrol regulates iNOS to inhibit atherosclerosis in C57BL/6J mice[J];中国病理生理杂志;2015-09
4 LU Xiaoling;YOU Haoyuan;HUANG Cuilan;LIU Chengyuan;Department of Surgery,Yushui District Maternal and Child Care Service Centre of Xinyu City in Jiangxi Province;Department of Trauma Emergency, the First Hospital Affiliated to Nanchang University;;Effects of acute alcoholism on blood gas analysis in rabbits[J];中国现代医生;2014-35
5 YOU Hao-yuan;HUANG Cui-lan;LIU Cheng-yuan;LU Xiao-ling;HUANG Liang;Department of Emergency,the First Affiliated Hospital of Nanchang University;Department of General Surgey,Maternal and Child Health Hospital of Yushui District of Xinyu;;Effect of Acute Alcohol Poisoning on Inflammatory Mediators in Rabbits with Hemorrhagic Shock[J];南昌大学学报(医学版);2014-11
6 LIN Jianjun;ZHANG Zicheng;YANG Yong;Shandong Institute of Pharmaceutical Technicians;Shandong University of Traditional Chinese Medicine;Xinyan Central Hospital of Yanzhou;;Research of Dynamic Efficacy on the Rat Acute Myocardial Infarction Model with CK and TNF-α Differential Expression by Sini Decoction[J];四川中医;2014-08
7 WANG Xiao-li;DONG Miao-xian;XU Tian-jiao;LI Cheng-chong;SUN Ji-kai;LI Xiao-ming;Qiqihar Medical College;Changchun University of Chinese Medicine;;Protective effect of β-asarone on primary rat hippcampal neurons against hypoxia/hypoglycemia and reperfusion injury[J];中国病理生理杂志;2014-05
8 Wang Di;Liu Hongbai;Heilongjiang River Fisheries Research Institute/Chinese Academy of Fisheries Sciences;;Effects of Prescription A on Anti-oxidation Capability in Amur sturgeon (Acipenser schrencki Brandt.)[J];中国农学通报;2013-32
9 LI Shao-wu,WANG Di,LU Tong-yan,LIU Hong-bai(Heilongjiang River Fisheries Research Institute,Chinese Academy of Fishery Sciences,Harbin 150070,China);Effects of Three Chinese Medicinal Herb Complex Additives on Antioxidation in Amur Sturgeon(Acipenser schrencki Brandt)[J];水产学杂志;2012-03
10 DONG Xiang,HU Rong,LV Xiang,LI Qi-fang,JIANG Hong,ZHU Ye-sen(Department of Anesthesiology,the Ninth People's Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200011,China);Protective effect of isoflurane posttreatment on acute lung injury induced by sepsis in rats[J];上海交通大学学报(医学版);2012-03
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 ;舒芬太尼对大鼠心肌缺血再灌注中Toll样受体4以及肿瘤坏死因子α的影响[J];当代医学;2013-17
2 HUANG Wen-dong1,YANG Yong-fei1,CHEN Jian-wen2,ZHU Bang-hao1(1.Cardiovascular Research Center,Zhongshan School of Medicine,Sun Yat-sen University,Guangzhou 510080,China; 2.Pharmacology and Toxicology Laboratory,College of Pharmacy,Sun Yat-Sen University,Guangzhou 510089,China);Synergism of tanshinol and tetramethylpyrazine on cardiovascular system in rats[J];中国药理学通报;2013-03
3 XIONG Yan,ZHANG Mei,CHEN Fei,FANG Wei-jin(Guangzhou Research Institute of Snake Venom and Department of Pharmacology,Guangzhou Medical College, Guangzhou 510182,China.);Roles of mitochondrial dysfunction in cardiovascular diseases[J];中国病理生理杂志;2013-02
4 ZHANG Wei-hua,YU Xue,WANG Jing-xiao,WANG Yan-li,SUN Zhi-rui,LIU Li(Department of Pathophysiology,Harbin Medical University,Harbin 150081,China);Calcium sensing receptor is involved in neonate rat cardiomyocyte apoptosis induced by hypoxia/reoxygenation via regulating calcium concentration in mitochondria[J];哈尔滨医科大学学报;2012-06
5 ZHANG Jian-jun,ZHANG Zhen-ying,WANG Na(Weifang Peoples Hospital,Shangdong Weifang 261041,China);Effect and mechanism of action of hydroxysafflor yellow A on myocardial ischemia-reperfusion injury in rats[J];中国医院药学杂志;2012-19
6 REN Xiao-yu1,2,SUN Gui-bo3,ZHANG Qiang4,XU Hui-bo5,SUN Xiao-bo3(1.College of Pharmacy,Heilongjiang University of Chinese Medicine,Ha′erbin 150040,China;2.Eastern Liaoning University,Dandong Liaoning 118003,China;3.Institute of Medicinal Plant Development(IMPLAD),Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing 100193,China;4.Wenzhou Medical College,Wenzhou Zhejiang 325035,China;5.Jilin Academy of Traditional Chinese Medicine,Changchun 130011,China);Protective effects of PnGL on ischemia/reperfusion injury in isolated rat hearts[J];中国药理学通报;2012-01
7 Hui Liu1,Juan Su1,Xu Liang1,Xi Zhang1,Ya-Jun He2,Hai-Qiang Huang1,Ji Ye1,Wei-Dong Zhang1,2 1 Department of Natural Medicinal Chemistry,School of Pharmacy,Second Military Medical University,Shanghai 200433,China;2 School of Pharmacy,Shanghai Jiaotong University,Shanghai 200030,China;Identification and determination of the major constituents in traditional Chinese medicine Longdan Xiegan Pill by HPLC-DAD-ESI-MS[J];Journal of Pharmaceutical Analysis;2011-01
8 ZHANG Tian-ling, DING Su-ju, ZHAO Yu-wu (Department of Neurology, the Sixth People's Hospital of Shanghai, Shanghai 200433, China);Role of -Ketoglutarate Dehydrogenase in Skeletal Muscle Lesion of Diabetic Rats[J];医学临床研究;2010-04
9 ZHANG Hong-xia,WU Yong-jie,GAO Ming-tang Department of Pharmacology,School of Basic Medical Science of Lanzhou University,Key Laboratory of Preclinical Study of New Drugs of Gansu Province,Lanzhou 730000,Gansu,China;Protective effects of DDPH on myocardial ischemia reperfusion injury in isolated rat hearts[J];中国临床药理学与治疗学;2010-02
10 XU Chang-qing,ZHANG Wei-hua(Department of Pathophysiology,Harbin Medical University,Bio-pharmaceutical Key Laboratory of Heilongjiang Province,Harbin 150086,China. );Investigation progress of CaSR in cardiovascular system[J];中国病理生理杂志;2010-02
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 Wang Xiujuan;Zhong Xiaopeng;Ding Bo;Zhang Shiwu;Department of Emergency, Tianjin People's Hospital;;An experimental study on brain protective effect of Sini decoction on post-resuscitation syndrome[J];中国中西医结合急救杂志;2017-04
2 WANG Jing;WANG Hai-hua;ZHOU Ping-ping;JIANG Yu-xin;Department of Physiology,Wannan Medical College;;Regulation Mechanism of Ginkgo-Dipyridamolum for Calcium Homeostasis on Cardioprotective Effect During Ischemia Reperfusion Injury[J];中药材;2015-12
3 ZHAO Jianwen;WANG Zhiyong;YAN Guoqiang;ZHANG Yanwei;XIE Xinling;SONG Shuchang;Hebei Province Cangzhou Chinese and Western Medicine Hospital;;Experimental Research Progress of TCM on Vascular Dementia[J];辽宁中医药大学学报;2015-11
4 WANG Chun;LIU Li-mei;SONG Zhi-qian;DONG Yun-zhuo;DU Zhi-yong;NING Zhang-chi;LIU Yuan-yan;LIU Zhen-li;The Institute of Basic Theory,China Academy of Chinese Medical Sciences;School of Chinese Pharmacy,Beijing University of Chinese Medicine;;Survey of active components in commonly-used Chinese materia medica injections and related Chinese materia medica for cardiovascular disease[J];中草药;2015-15
5 ZHAO Lan-ping;XUE Shu-fang;CHEN Yan-jing;WANG Xue-fang;CHEN Li-feng;Department of Physiological,Hebei North University;Institute of Basic Theories,China Academy of Chinese Medical Sciences;;Effects of nitric oxide on spontaneous action potentials of guinea-pig left ventricular outflow tract under the conditions of ischemia/reperfusion[J];中国病理生理杂志;2015-07
6 RONG Xueying;GUO Hongmin;HUANG Xuxia;Nanjing University of TCM;;Treatment of SIRS by Chinese herbal compound[J];长春中医药大学学报;2015-01
7 LI Zhi-hui;YANG Chang-chun;HAN Ying;The First Department of South Building,the General Hospital of Chinese People's Armed Police Forces;Xinxiang Medical College;;Research Progress of Adiponectin and Vascular Endothelial Function Repair[J];医学综述;2014-10
8 Cai Mengmeng;Bao Hongguang;Si Yanna;Xu Li;Han Liu;Shi Tao;Wang Hongyu;Xie Xinyi;Department of Anesthesiology,Nanjing Hospital Affiliated to Nanjing Medical University(Nanjing First Hospital);;Effects of adiponectin pretreatment on CD11b expression and respiratory burst activity of peripheral blood polymorphonuclear leucocytes in septic rats[J];中华麻醉学杂志;2014-01
9 WANG Jing;JIANG Yu-xin;CUI Feng-juan;MIN Zhi-xue;ZHOU Ping-ping;WANG Hai-hua;Department of Physiology,Wannan Medical College;;Inhibitory effect of ginkgo-dipyridamole injection on ischemia/reperfusion injury in rat hearts in vitro[J];中国病理生理杂志;2013-09
10 Shi Yinglu,Ge Shenglin,Zhang Chengxin(Dept of Cardiovascular Surgery,The First Affiliated Hospital of Anhui Medical University,Hefei 230022);The protective role of nicorandil postconditioning in lung ischemia/reperfusion injury of rats[J];安徽医科大学学报;2013-07
【Secondary Citations】
Chinese Journal Full-text Database 9 Hits
1 LIU Yan 1, WU Wei-kang 2, YANG Cheng-ti 1, ZHAO Ming-qi 2, LUO Han-chuan 2 (? 1?Department of Cardiovascular of the Second Affiliated Hospital, Lanzhou Medical College, Lanzhou 730000,China; ? 2?Institute of Integrated Traditional Chinese and Western Medicine, Sun Yat-sen University of Medical Sciences, Guangzhou 510080, China);Liver protection by Sini decoction in hemorrhagic shock and its mechanism relating to oxygen free radical and nitric oxide[J];中国病理生理杂志;2003-06
2 HEI Zi-qing 1,2 , WU Wei-kang 1, SUN Hui-lan 1, HUANG He-qing 1, TAN Hong-mei 1, LUO Han-chuan 1 (? 1?Institute of Integrated Traditional Chinese and Western Medicine, Sun Yat-sen College of Medical Sciences,? 2?The First Affiliated Hospital of Zhongshan University, Guangzhou 510089, China);Effects of Sini decoction on atherosclerosis and ceramide content of aorta in rabbits[J];中国病理生理杂志;2003-03
3 SU Pixiong *, GUAN Yingpeng, YOU Bin, et al. * Heart Center, Beijing Chaoyang Hospital,Beijing 100020;Stereological studies of myocardium in different types of rheumatic vavular diseases[J];中华胸心血管外科杂志;2000-06
4 LHO Han-Chuan, HUANG He-Qing, LIU Xiao-Xia, CHEN Jian-Ping, TAN Hong-Mei, YANG Hui, TANG Tie-Jun, LIANG Tian-Wen,WU Wei-Kang Department of Pathophysiology, Sun Yat-sen University of Medical Sciences, Guangzhou (510089);Experimental research on the protective effect of SiNi decoction on acute ischemic myocardium[J];中国病理生理杂志;1999-11
5 Huang Luosheng; Zhao Weichun; Xia Yufeng(School of Traditional chinese Medicines, Nanjing 210038;Institute of Drug Inspection,Tianjing 300070);Effect of Preparation Methods on the Content of Alkaloids and Glycyrrhetic Acid in Sini Injection[J];中国药科大学学报;1999-05
6 JIANG Lan, ZHAO Xiu-Mei, TIAN Niu, LIU Yu-Ying, LI Xiang-Hong, JIANG Chao-Guang Lab of Microcirculation, Chinese PLA General Hospital, No. 28 Fuxing Road, Beijing (100853);Simulation study of hemodynamic of small intestinal villosity microvessels in vitro[J];中国病理生理杂志;1999-01
7 WU Wei-Kang,HOU Can,LUO Han-Chuan,CHENG Chao,TAN Hong-Mei Department of Pathophysiology,Sun Yat-sen University of Medical Sciences,Guangzhou(510089);Effects of Sini Decoction improving energy metabolism of ischemic myocardium and mechanisms of the effects[J];中国病理生理杂志;1998-06
8 Wu Wei-kang Yang Kun Wu Jin-lang Dept.of Pathophysiology,Sun Yat-sen University of Medical Sciences,Guangzhou(510089);Uitrastructural Observation of Protective Effects of Sini Decoction(四逆汤)on Ischemic Myocardium[J];中国中西医结合杂志;1995-S1
9 Wu Weikang;Luo Hanchuan and Hou Can(Sun Yatsen University of Medical Sciences,Guangzhou 510089);In Vitro Experiment on Scavenging Oxy-radical and SuppressingMyocardial Lipid Peroxidation with Sini Decoction[J];中国中药杂志;1995-11
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved