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《CHINESE JOURNAL OF PATHOPHYSIOLOGY》 1994-01
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Protective effect of radix salviae miltiorrhize on ethanol-induced gastric mucosal damage in rats and mechanism

Chang Jiang,Deng Chang-Sheng,et al Gastroenterology Department ,the Second Affiliated Hospital,Hubei Medical Uaiversity,Wuhan  
The protective effect of radix salviae miltiorrhize ( RSM) on gastric mu-cosa and its mechanism were studied by observing the effects of RSM on the ethanol-induced gastric mucosal lesions,gastric mucus, gastric emptying in rats,and its relation toindomethacin and exogenous PGE_1. The results indicated that RSM could protect gastricmucosa from absolute ethanol-indnced damage and increase gastric mucus secretion in rats.Pretreatment with indomethacin could partly abolish this effect, and intragastric abminis-tration of exogenous PGE_1 analogue could restore this effects.It was suggested theseeffects were mediated partly by the increased endogenous PGs stimulated by RSM.Amber-lit pellets were given intragastrically to quantify gastric emptying of solid s a nd the re-sults showed that RSM inhibited gastric emptying and reduced gastric mucosal folds so asto protect the gastric mucosa against ethanol-induced damage.
【CateGory Index】: R573.102
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【References】
Chinese Journal Full-text Database 6 Hits
1 Yi Shouxiang,et al (Research Institute of Acupuncture and Merdian,Changsha 410007);EXPERIMENTAL OBSERVATION ON PROTECTIVE EFFECT OF DYNAMIC EXCITING ON EVERY POINTS IN FOOT YANGMING CHANNEL ON GASTRIC MUCOSA OF RAT[J];JOURNAL OF HUNAN COLLEGE OF TRADITIONAL CHINESE MEDICINE;1996-04
2 LI Daohua,ZHANG Xiufang,HAO Lei(Department of Traditional Chinese Medicine,Qiaolian Hospital of Shandong,Zibo 255031,China);Effect of repeat use of radix et rhizoma salviae miltiorrhizae on healing time and relapse rate in patients with gastric ulcer[J];Journal of North China Coal Medical University;2008-03
3 CHEN Jian-yong,PAN Feng,LI Xiao-ling,et al(Zhejiang Provincial Hospital of Integrative Chinese and Western Medicine,Hangzhou310003);EFFECTS OF JIANWEI MIXTURE ON GASTRIC MUCOSAL BLOOD,6-KETO-PGF_(1α) AND TXB_2 IN RATS WITH ACUTE EROSIVE GASTRITIS BY NSAIDS[J];Chinese Journal of Traditional Medical Science and Technology;2008-04
4 ZHANG Xiang-rong, WANG Yan, YIN Feng-qiang, LI San-ming (Pharmaceutical College of Shenyang Pharmaceutical University, Shenyang 110016, China);Study on preparation of total salvianolic acids gastric residential Tablets[J];Chinese Traditional Patent Medicine;2003-05
5 ZHENG Li min, LIU Xiao ling, XIA Zhong yuan Shenzhen Municipal Central Hospital, Guangdong (518036);Clinical Observation on Gastrointestinal Protective Effect of Composite Salviae Injection in Patients Undergoing Cardio-Pulmonary Bypass Heart Surgery[J];Chinese Journal of Integrated Traditional and Western Medicine;2001-03
6 SONG Zhi-ren LIU Zhi-yun CHENG Lu, The Third Surgical Department,The 169 th Hospital of PLA,Hunan(421002);Effect of Combined Therapy with Kangyanling and Omeprazole on Digestive Dysfunction in Burned Patients[J];Chinese Journal of Integrated Traditional and Western Medicine;2008-03
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 YE Fang,XU Xin-rong(Emergency Department of Magang Hospital ,Maanshan 243000);The alteration and significance of thrombomodulin in hearts and lungs during traumatic shock of rats[J];Anhui Medical and Pharmaceutical Journal;2005-08
2 Liu Yong,Xu Guansun (Anhui College of TCM,Hefei 230038,China);PROTECTIVE EFFECT OF ELECTROACUPUNCTURE AT ZUSANLI ON STRESS-GASTRIC MUCOSAL DAMAGE IN RATS[J];JOURNAL OF ANHUI TRADITIONAL CHINESE MEDICAL COLLEGE;2000-02
3 Pei Wenfen Xu Guansun Sun Yong Wang Yuefang Zhu Shunli Zhang Daoqin (Department of Physiology,Anhui College of TCM,Hefei 230038) ;THE PROTECTIVE EFFECT OF ELECTROACUPUNCTURE AND MOXIBUSTION ON THE GASTRIC MUCOSAL DAMAGE AND THE RELATION WITH NITRIC OXIDE IN RATS[J];JOURNAL OF ANHUI TRADITIONAL CHINESE MEDICAL COLLEGE;1997-04
4 WU Yong-Fang YING Yun MAO Sun-Bo (Wuhan Postgraduate Medical College, Wuhan, 430016);A CLINICAL TRIAL OF THE EFFECTIVENESS OF HYDROXYCAMPTOTHECIN COMBINED WITH SALVIA MITORRHIZA FOR CANCERS OF THE DIGESTIVE SYSTEM[J];Chinese Journal of Cancer;1990-03
5 SONG Bo-gen LY Yi-qing ZHAO Gui-fen SHI Hong-jun ZHU Qing-yan (Lab. of Cancer Research,, Shanghai Railway Medical College, Shanghai 200070);THE TRAUMATIC DEGREE OF GASTRIC MUCOSA AND PATHOGENESIS OF GASTRIC CANCER[J];Chinese Journal of Cancer;1993-05
6 XU Li chun1*, SUN Zhen hua1, CHEN Zhi lin1, CHEN Ping2, LIU Xiao dan3, BU Pin1 1. Institute of Traditional Chinese Medicine and Western Medicine, Yangzhou University, Yangzhou 225001, P.R.China 2. Shubai Peoples Hospital of Jiangsu Province, Yan;Antitumor Effect on Murine B16 Melonama by Tumor Cell Vaccine Modified with SE (Chinese Traditional Medicine, SAN LENG and E SHU)[J];Chinese Journal of Cancer;2001-12
7 Liu Chengzhe,Liu Mulin (Yu Ji Hospital of Lingbi,Anhui 234200 );Protective effect of rhubarb on barrier of intestinal mucosa in early stage of experimental multiple organ failure(MOF)[J];JOURNAL OF BENGBU MEDICINAE COLLEGE;1998-06
8 Yan Maoxiang ; Chen Zhiyun ; Cao Junmin , et al(The Affiliated Hospital to Zhejiang College of TCM, Hangzhou 310006);The Influence of Wei Er Kang on Immunologic Function in Rats[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;1998-03
9 Li Xiaoguang,Ye Fuqiang △Xu Honghua △Medical College,Jinan University,Guangzhou(510632) △Guangzhou University of Traditional Chinese Medicine;Studies on Pharmacological Effects of Bornyl Acetate[J];Journal of Zhejiang College of Tcm;2001-03
10 YANG Xuesong; LI Yinong; YE Simao; DONG Xiuyun(Department of Gastroenterology, The Third Hospital,Beijing Medical University 100083);EXPERIMENTAL STUDY OF CORRELATION OF GASTRIC ULCER HEALING QUALITY WITH RISISTANCE TO REINJURY BY PREDNISONE IN RATS[J];Journal of Beijing Medical University;1996-06
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 Liu Yuling , Chen Xiaying , Chen XuLin, et al.Department of Experimental Surgery Laboratory of the First Clinical College in Anhui Medical University , Hefei , 230032;Effect of salvia miltiorrhizae on water content in rats during early postburn stage[J];;2006-03
2 HU Wen-bin1,WU Shu-mei2,XUE Ben-chun1,SU Zeng-feng1,YANG Jin-peng1,YANG Ren-min1(1.The Affiliated Hospital,Institute of Neurology,Anhui College of Traditional Chinese Medicine,Hefei,Anhui 230061;2.Department of Neuropathy,Chaohu Second People′s Hospital of Anhui Province,Chaohu,Anhui 238000);Effect on index of hepatic fibrosis in serumology by combined use of kushenin and decopper therapy in treating hepatolenticular degeneration[J];Anhui Medical and Pharmaceutical Journal;2008-11
3 Wang Changsong Zhejiang Chinese Medical University,Hangzhou(310053);Chronic Atrophic Gastritis Therapy of Traditional Chinese Medicine[J];Journal of Zhejiang University of Traditional Chinese Medicine;2006-04
4 Hu Yonghua Chen Wei Cheng Zhengxiong(NO.6 Hospital of Changsha,410000,China);Observation on Clinical Efficacy of Modified Salvia Decoction in Treating Peptic Ulcer with Blood Stasis Syndrome of 76 Cases[J];Journal of Changsha Medical College;2008-01
5 Jie ZHAO,Xiao-Mei TONG.Department of Pediatrics,Third Hospital of Peking University,Beijing 100083,China;Prophylactic effect of radix salvia miltiorrhiza on gastric stress ulcer in young rats[J];The Chinese Journal of Contemporary Pediatrics;2005-06
6 Zhang Deyu et al (Department of Internal Medicine,the 60th Hospital of PLA,Dali 671000);Clinical Analysis in 185 Gerontal patients with Peptic Ulcer[J];JOURNAL OF DALI MEDICAL COLLEGE;1997-03
7 ZHU Xiong Xiang, TANG Chao Wu, CHEN Bi Department of Burn Surgery, Center of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710033, China;Effect of burn patient's serum and Salvia miltiorrhiza on chemiluminescence magnitude of normal blood polymorphonuclear neutrophils[J];JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY;1999-10
8 ZHANG Zhi-ping1, YOU Ting-ting2, ZOU Li-yi2, WU Tie2, WU Yi2, CUI Liao2 1Department of Histology and Embryology, 2Departmet of Pharmaceutics, Guangdong Medical College, Zhanjiang 524023, China;Effect of a compound Danshen preparation in preventing long-term gastric lipid emulsion administration-induced nonalcoholic steatohepatitis in rats[J];Journal of Southern Medical University;2008-07
9 WANG Jun dong,LI Shu qin,SHEN Rui ling,WANG Jian ling (College of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu,030801,China);Effects of Four kinds of Chinese Medicinal Recipes on Part Characteristic in Broiler[J];Progress In Veterinary Medicine;2002-04
10 Li Zhijun, XIN Jianjun. Affiliated Hospital of Chinese and western medicine school,Anyang City,Henan Province 455000;Therapeutic effect of acupoint injection in treating 42 patients with diabetic neuropathy[J];Hebei Journal of Traditional Chinese Medicine;2001-11
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