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Effects of Verapamil and Anisodamine on pathologic changes of passive Heymann nephritis in rats

Wang Ying-Wei,Hao Xing-Zhi,et al Department of Immunopathology,Xuzhou Medical College,Xuzhou  
An animal model of passive Heymann nephritis(PHN)in rats was madewith the antiserum against renal tubular antigen(Tub-Ag)of rats.Verapamil andAnisodamine were chosen to treat the rats with PHN and effects of these two drugson pathologic changes in PHN were observed.The results showed that proteinuria in grouptreated by Verapamil or Anisodamine was apparently lower than that in group ofPHN.The tissue injuries in groups treated by these two drugs were ameliorated to acertain extent.The results suggested that these two drugs had curative effects to thepathologic changes of PHN in rats.
【CateGory Index】: R965.1
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