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The effects of cerebral ischemia on myocardium in different month-age rats

Ma Ning, Zhang Bei-Qi, et al Hebei Academy of Medical Sciences,Shijiazhuang  
The aim was to confirm the effects of cerebral ischemia on myocardium in different month-age rats.40 rats each in 18-24 months age and 3-4 months-age group were divided further into the cerebral ischemic group and control group. The cerebral ische- mic model were established by catheterization of left middle cerebral artery. Three hours after cerebral isckemia,pathology,SOD,MDA,NAGase,platelet gather forces and cerebral ischemic sizes were examined.The results showed that after cerebral ischemia,all index showed unusual changes. But the degree of damage in the old age group was far more serious than that of the adult group.It appeared that pathologic damage severes,SOD level decreased,MDA content increased,NAGase activiy going up,platelet releasing forces redu-ced and so on. It was suggested that after cerebral ischemia the myocardium damages in old rats was more serious.
【CateGory Index】: R363.273
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