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《Chinese Traditional Patent Medicine》 2001-05
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Effect of LBP on Expression of c-myc Oncogene of Senile Mice

CHEN Zhi-song1, NONG Zhi-fei2, WU Zhi-kui1, CAI Yong-chun1, WANG Lei1 (1. Laboratory of Molecular Biology, Guanganmen Hospital, China Academy of Traditional Chinese Medicine, Beijing 100053, China; 2. First Affiliated Hospital of Guangxi College of  
Objective:To study the molecular mechanism of anti-senile effect of lycium barbarum polysaccharides (LBP). Methods:After natural senile mice and D-gal-induced senile mice were given LBP for two months and a month respectively, the expression changes of c-myc oncogene in marrow cells of all mice were measured by the techniques of semi-quantitative reverse transcription and polymerase chain reaction (RT-PCR).Results: The expression of c-myc oncogene of natural senile mice and D-gal's-induced senile mice were significantly higher than those of young and nomral mice (P0.001). After medication, LBP obviously inhibited the change (P 0.05).Conclusions: One of molecular mechanisms of anti-senile effect of LBP is to inhibit the expression of c-myc oncogene.
【CateGory Index】: R285.5
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【References】
Chinese Journal Full-text Database 9 Hits
1 WU Jian-zhang,XIAO Yi-jun,CHEN Bing-hua,ZENG Hong(College of Life Sciences,Fujian Normal University,Fuzhou 350108,China);Study on the Anti-S_(180) Sarcoma of Nerium indicum Mill.Polysaccharide in Mice[J];Journal of Fujian Normal University(Natural Science Edition);2009-04
2 CHEN Qing-wei~1,CHEN Zhi-tao~2(1.Fuzhou Institute for Drug Control,Fuzhou 350007;China,2.Fuzhou Changfuxing Pharmaceutical Development Co.,Ltd.,Fuzhou 350002;China);Progress of Studies on the Pharmacology Effect of Lycium Barbarum polysaccharides[J];Strait Pharmaceutical Journal;2005-04
3 ZHAO Long-po~(1),XU Zheng~(2),ZHANG Mei~(1),SUN Hui-chen~(2),TANG Fei~(2) 1.Department of Pathology,2.Department of Clinical Experiment,Bethune International Peace Hospital,Shijiazhuang,Hebei 050082,China;Effects of Fructus Lycii and Radix Astragali on the Function of Sertoli Cells in Rat Testes[J];National Journal of Andrology;2007-01
4 Liao Hui1,Liu Jinghua1,Qian Huijun2,Lv Shengqi2 1.Department of Urology,Xiang fan Hospital Affiliated to Hubei College of TCM,Xiang fan 441000,China 2.Department of Urology,Renmin Hospital of Wuhan University;Effect of Sheng Jing He Ji mixture on pituitary-sexual gland axis[J];Chinese Journal of Andrology;2008-08
5 ZHENG Qin,FENG Yi~*,XU De-sheng(Shanghai University of Traditional Chinese Medicine,Shanghai 201203;China);From Aspect of Polysacchrides to See Pharmacologic Activities of Yin Tonifying Herbs[J];LiShiZhen Medicine and Materia Medica Research;2006-11
6 YU Lei,WANG Jian-feng,LIU Li-bo,et al.MH Radiobiology Research Unit,School of Public Health,Jilin University(Changchun 130021,China);Study on anti-irradiation damage activities of lycium barbarum L[J];Chinese Journal of Public Health;2007-10
7 Zhang Dongjie1 Feng Kun1,2(1College of Food Science,Heilongjiang August First Land Reclamation University,Daqing 163319 2College of Biological Science,China Agricultural University,Beiijing 100094);Primary Study on the Antitumer Activity of Alfalfa Polysaccharides[J];Journal of Chinese Institute of Food Science and Technology;2006-06
8 XU Shun-lin 1 , HUANG Jun 1 , TIAN Geng-yuan 2 (1.Department of Cardilolgy, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China;2.Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032,China);Effects of LbGp on the intracellular free calcium concentration of cardiomyocytes induced by hypoxia and KCl[J];China Journal of Chinese Materia Medica;2005-07
9 ZHAO Long-po,XU Zheng,ZHANG Wen,SUN Hui-chen~*,TANG Fei(Bethune International Peace Hospital,Hebei Shijiazhuang 050082,China);The Effect of Fructus Lycii and Radix Astragali on Synthesis of Inhibin in Sertoli Cells of Rat Testis[J];Chinese Journal of Experimental Traditional Medical Formulae;2007-01
【Citations】
Chinese Journal Full-text Database 4 Hits
1 LIUYutao;ZNOUHe;BAIXiaowei ;YLNJinzhu(Department of Immunology. Beijing McdicalUniveraity 100083);THE REGULATION OF LYCIUM BARBARUM POLYSACCHARIDE ON APOPTOSIS OF MOUSE THYMOCYTE IN VITRO[J];JOURNAL OF BEIJING MEDICAL UNIVERSITY;1996-02
2 Xin Shantian;Geng Changshan;Zhou Jinhuang Institute of Pharmacology and Toxicology,Academy of Military Medical Sciences;IMMUNOPHARMACOLOGICAL RESEARCH AND USAGE OF ACTIVE INGREDIENT OF TONICS IN TRADITIONAL MEDICINE[J];Bulletin of the Academy of Military Medical Sciences;1988-03
3 Li Guoli, Huang Yuanqing, Ren Binbin, et al Dept. of Nutrition and Food HYgiene, Ningxia Medical College,Yinchuan, 750004.;The Effect of Lycium Barbarum Polysaccaride on Endurance andAntioxidative Status in Trained Mice[J];CHINESE JOURANAL OF SPORTS MEDICINE;1998-01
4 Zhang Xin, Xiang Shulin, Yin Yimin, et al. Department of Immunology,Beijing Medical University,Beijing 100083;Effect of lycium barbarum polysaccharide(LBP) on apoptosis of murine thymocytes[J];CHINESE JOURNAL OF MICROBIOLOGY AND IMMUNOLOGY;1997-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LIU Mei(Department of Life Sciences,Zaozhuang University,Zaozhuang,Shandong 277160);Effects of Lycium chinese Mill Extracts on the Life-span of Drosophilae and Their SOD Activities and MDA Content[J];Journal of Anhui Agricultural Sciences;2010-04
2 MA Chun-yan 1,CAO Jian-min 2,WANG Lin 2,ZHAO De-ling 2,FAN Qin-min 2 (1.Baotou Normal College,Baotou 014030,Inner Mongolia,China;2.Beijing Sport University,Beijing 100084,China);A Study of Effects of Increasing Load Training on Free Radical Metabolization in the Tissue of Rats Changes and Nutrition Interference[J];Journal of Beijing Sport University;2008-03
3 Sun Wenjuan;Sui Dayuan;Yu Xiaofeng;et al(Dept. of Pharmacol.,N.B. Univ.of Med.Sci.);Preliminary pharmacological studies of polysaccharide-proteins from Lycium barbarum[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;1996-05
4 SHAN Anshan,MA Deying,LI Qundao,ZHU Zhengpeng ZHAO Yun,GUO Xiaoqiu,YAN Junshu (Institute of Animal Nutrition, Northeast Agricultural University, Harbin 150030, China);Nutritional and regulatory function of Chinese medical herbs and its extracts[J];Journal of Northeast Agricultural University;2007-01
5 LIU Fa-quan, ZHANG Ji-ren, XU Xiao-ping, LI Peng (Department of Oncology, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China);Effect of NADH on apoptosis during radiation injury of liver cell line L02[J];Journal of First Military Medical University;2001-08
6 JIN Shao-lin,GUAN Hong,HE Xiu-ling,LI Pei-feng (College of Animal Science and Veterinary Medicine,Inner Mongolia Agriculture University,Huhhot,Inner Mongolia,010018,China);Influences of Taurochenodexycholic Acid on the Apoptosis of Different Immunocytes[J];Progress in Veterinary Medicine;2007-06
7 GUO Feng-ying1, LI Pei-feng2(College of Animal Science and Medicine, Inner Mongolia Agricultural University,Huhhot,Inner Mongolia,010018,China);Effect of Taurocholic Acid on Thymocyte Apoptosis in Mice[J];Progress in Veterinary Medicine;2008-03
8 ZENG Yun,FANG Hui-lin,YANG Kai(College of Animal Science and Technology,Guangxi University,Nanning 530005,China);Effect of extracted RHIZOMA COPTIDIS on apoptosis of mice thymocyte[J];Journal of Guangxi Agricultural and Biological Science;2007-01
9 HUANG Pei-chi1,WANG Juan2(1.Jiangsu Province Xuzhou Medical Vocational College,Xuzhou 221116,China;2.Xuzhou Higher Vocational School of Bioengineering,Xuzhou 221004,China);The protective effects of LBP extraction on acute liver Injury caused by CCl_4[J];Strait Pharmaceutical Journal;2009-10
10 Fu yanli, Science and Research Institute of Harbin Pharm Group Co., The Sixth Pharmaceutical Medicine Factory, Heilongjiang Harbin 150010;Determination of the Concentrations of Polysaccharide in Gou Qi from different areas and grades by Colorimetry[J];Heilongjiang Medical Journal;2002-04
China Proceedings of conference Full-text Database 2 Hits
1 Li xuhui~1 Fan xiaomei~2 Yu yang~3 1 Physical Education School,Inner Mongolia Normal University,Huhhot 010022; 2.Inner mongolia Medical College,Huhhot 010022; 3.Shenyang Institute of Physical Education,Shenyang 110032;Influence of Chitosan on Free Radical Metabolism in Erythrocytes of exhaustive swimming rats[A];[C];2007
2 Qin xiaoming 1; Lin Huajuan1, Ning Enchuang 2 (1 College of Food Science and Technology, guangdong Ocean University, Zhanjiang, 524088); 2 Light Industry and Food Engineering Institute, Guangxi University, Nanning, 530005);Isolation and characterization of araban from the fruit of Lycium chinense Mill.[A];Chinese Society of Agricultural Engineering[C];2005
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LI Feng et al(Biotechnology and Science College,Shenyang Agricultural University,Shenyang,Liaoning 110161);Study on Elimination Protein from the Roofs of Aralia continentalis Kitag Polysaccharide[J];Journal of Anhui Agricultural Sciences;2006-01
2 WANG Jun jie, YU Li zhang, SHEN Wen jiang, et al The First Teaching Hospital of Beijing Medical University,Beijing 100034,P R China$$$$;The study of the influence of Kang Lai Te injection on radiosensitivity of renal carcinoma cell lines and its mechanism[J];CHINESE JOURNAL OF CANCER;1999-06
3 YANG Li,ZHU Xia,RAN Li Department of Oncology,Affiliated Hospital,Guiyang Medical College,Guiyang,Guizhou,550004,P. R. China;Correlations of HER-2,PCNA,Bcl-2,and Bax Expression to Prognosis of Breast Cancer[J];Chinese Journal of Cancer;2007-07
4 DING Shouyi, YANG Ying \ Department of Microbiology, Qingdao University Medical College, Qingdao 266021;EFFECTS OF POLYSACCHARIDES FROM SPIRULINA PLATENSIS ON THE GROWTH OF Hela CELLS: AN IN VITRO STUDY[J];Acta Acadimae Medicinae Qingdao;2002-04
5 Yao Zhenmin,Xiong Yaokang,Li Jianping Zhejiang College of TCM,Hangzhou(310009);Exper imental Study on Biejia Jian Oral Liquid's Anti fibrosis in Liver[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;2000-01
6 Xu Chengshui(徐承水) Department of Biology,Qufu Normal University,Shandong Qufu(273165);Effects of The Lycium Chinese Mill.(LcM.)on The Endurance Capacity of Mice[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;2000-04
7 Gong Bin; Li Yumei; Ma Jun(Shanghai University of Chinese Traditional Medicine, Shanghai 200032);Effect of Variously Processed Kidney-benefiting Chinese Herbal Medicine on Acetylcholinesterase Activity and M-cholinergic Receptor in the Brain of Demerntia Mice[J];LABELED IMMUNOASSAYS AND CLINICAL MEDICINE;1997-03
8 Yang Ke 1,Li Yang 1,Li Feng 1,Zhao Dan 1,Zhao Xuejian 1,Pei Haihong 2,Chen Yanping 3,Ma Xingyuan 3 (1 Dept.of Reproductive Pathophysiology,NBUMS ChangChun,130021;\ 2\ Dept. of Physical Exercise,NBUMS;\ 3\ Dept. of Natural Medicine,NBUMS) 〔;Effects of PDS on exercise-induced low serum testosterone in rats[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;2000-02
9 SHI Lei 1, WANG Yong 1,SHI Yong 2, LI Juan 2, LIU Zhi qiang 1, LIU Shu ying 1 (1. Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022,China;2. School of Public Health, Jilin University);Observation of Polysaccharide from Ornithogalum caudatum Ait. under Atomic Force Microscope[J];Journal of Norman Bethune University of Medical Science;2003-01
10 FENG Ting,HE Cong-fen,ZHAO Hua,DONG Yin-mao(College of Chemical and Environmental Engineering, Beijing Technology and Business University, Beijing 100037, China);REVIEW ON STUDIES OF PLANT POLYSACCHARIDES[J];Journal of Beijing Technology and Business University (Natural Science Edition);2004-05
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 SUN Na et al(Shengyang Agricultural University,Shengyang,Liaoning 110161);Antitumor of Polysaccharide and its Application Prospect in Divestock[J];Journal of Anhui Agricultural Sciences;2007-20
2 JIANG Jian et al (Department of Bio-technology Engineering,Dalian Nationalities University,Dalian,Liaoning 116600);Spectrometric Determination of Microelements in Alfalfa Leaves[J];Journal of Anhui Agricultural Sciences;2008-28
3 JIANG Jian et al(Department of Bio-technology Engineering,Dalian Nationalities University,Dalian,Liaoning 116600);Analysis of Amino Acids Compositions and Contents in Different Parts of Alfalfa[J];Journal of Anhui Agricultural Sciences;2008-29
4 MA Li-ping et al(College of Food and Biological Engineering,Henan University of Science and Technology,Luoyang,Henan 471003);Research on the Isolation Condition of Militaris Protoplast[J];Journal of Anhui Agricultural Sciences;2008-33
5 ZHENG Yan1,WANG Liang-xin2,WANG Hui1,SHI Mei1,SHI Xue-qin1, GUO Qing-mei3 (1.College of Life Sciences,Institute of Traditional Chinese Medicine Resources,Anhui Normal University,Wuhu 241000,China;2.Department of Pharmaceutical Sciences,Jiamusi University,Jiamusi 154003,China;3.School of Pharmaceutical Sciences,Shandong University of Traditional Chinese Medicine;Jinan 250355,China);Discussion on Building Chinese Medicinal Resources in Biology Specialty in Normal Universities[J];Journal of Anhui Normal University(Natural Science);2009-03
6 LUO Qing,LI Xiao-ying,HE Jun,WU Peng-ju,BEI Zhan-lin,QU Ling,CAO You-long(Engineering and Technology Research Center of Lycium barbarum L.,Ningxia Academy of Agricultural and Forestry Sciences,Yinchuan Ningxia 750002,China);Preliminary Study on Effect of the Eco-fertilizer NutriSmart on the Yield and Quality of Lycium barbarum L.[J];Northern Horticulture;2007-09
7 JIANG Jian,YANG Bao-ling,WANG Bing,MA Kun,HE Yong-xiang (College of Life Science,Dalian Nationalities University,Dalian Liaoning 116605,China);Determination of Trace Elements in Alfalfa by Flame Atomic Absorption Spectrophotometry[J];Journal of Dalian Nationalities University;2008-05
8 Jia YOU, Chengping HU, Qihua GU, Hongzhong YANGDepartment of respiratory medicine, Xiangya hospital, Centre-south University, Changsha 410008, china;Th1/Th2 Cells Immunomodulatory Effection of EGCG and PS-T on Non-small Cell Lung Cancer[J];Chinese Journal of Lung Cancer;2009-06
9 LI Kai,TAO Jing,LI Tao,et al.Pancreatic Surgery Center,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China;Effect of trametes robiniphila murr on the immune function of the patients with pancreatic cancer subject to resection[J];Journal of Abdominal Surgery;2007-02
10 LI Chao,PAN Jian-ming,ZHANG Xiang-nian,DENG Wei-jie,SHI Lei (Department of Pharmacy,Guangzhou General Hospital of Guangzhou Military Area Command,Guangzhou,Guangdong 510010,China);Study of teratogenicity of compound medlar oral solution in pregnant rats[J];Journal of Guangdong Pharmaceutical College;2009-04
China Proceedings of conference Full-text Database 1 Hits
1 GAO Hong, Gu Wen-ying, Ding Xiao-lin (Food School of Sounthern Yangtze University, Wuxi Jiangsu, 214036, China);Studies on Antitumor Activities of Ethanol Extracts from Liquid-Cultured Mycelium of Agaricus brasiliensis sp.[A];[C];2005
【Secondary Citations】
Chinese Journal Full-text Database 5 Hits
1 Li Xueru,Zhou Ya, Wang Qi, Xue Xiaofang(Dept. of Microbiol., Ningxia Med. Coll.);REGULATION OF LYCIUM BARBARUMPOLYSACCHARIDES ON IMMUNOFUNCTION IN MICE[J];NINGXIA MEDICAL JOURNAL;1994-04
2 Gu Rongrui; Guo Lin; Gu Minjie, et al (Shandong institute of Physical Education );RESEARCH ON MECHANISM OF ARTERIOSCLEROSIS AND THE INFLUENCE OF DIFFERENT INTENSITY OF EXERCISE ON IT[J];CHINESE JOURANAL OF SPORTS MEDICINE;1994-02
3 Zhang Xi (Beijing Military General Hospital 100700) Xie Xianchun (The Fourth Military Medical University, Xi'an 710033);Experimental Research on the Role of LyciumBarbarum Polysaccharide in Anti-peroxidation[J];China Journal of Chinese Materia Medica;1993-02
4 Zhou He, Duan Danxia, Yin Yimin, et al Department of Immunology, Beijing Medical University, Beijing 100083;APOPTOSIS(PCD) OF MURINE THYMOCYTES INDUCED BY ANTI-CD4 McAb IN VIVO[J];Chinese Journal of Microbiology and Immunology;1995-06
5 Ding yan;Xin Shan-tian;Zhou Jing-huang Inst of pharmacol Toxicol, Acad Millit Med Sci, Beijing;Stimulation of ~3H-thymidine Incorporation into T and B Cells and Inducement of Interferon in vivo onMice by Epimedium Polysaccharide[J];Chinese Journal of Immunology;1985-06
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