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《Chinese Traditional Patent Medicine》 2005-07
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Effect of Gardenia jasminoides Ellis on serum IL-1β and TNF-α of rheumatoid arthritis rats

ZHU Jiang, XIE Wen-li, JIN Yu-zhang, SUN Wen-jun, GAO Xin (Department of Pharmacology, MedicaJ College of CPAPF, TianJin 300162, China)  
AIM To study the effect of Gardenia jasminoides Ellis on serum IL-1β and TNF-α level of rheumatoid arthritis rats, as well as its mechanism. METHODS An experimental type Ⅱ collagen-induced arthritic rats was established. The inhibitory effects on paw edema were observed, and serum IL-1β and TNF-α levels were determined in experimental rats. RESULTS Compared with models, Gardenia jasminoides Ellis inhibited paw edema on rats significantly, and the levels of serum IL-1β and TNF-α showed markedly decrease by Gardenia jasminoides Ellis at high dose to medium dose( P 0.01). CONCLUSION Gardenia jasminoides Ellis could significantly lower serum IL-1β and TNF-α levels in rheumatoid arthritis rats, and its effect has a close relation with inhibitory development of rheumatoid arthritis.
【Key Words】: Gardenia jasminoides Ellis rheumatoid arthritis IL-1β TNF-α
【Fund】: 武警部队科研基金资助课题:200054
【CateGory Index】: R285.5
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【References】
Chinese Journal Full-text Database 10 Hits
1 ;Effect of Gardenia Gasminoides Ellis on pathology of articular cartilage and IL-1β expression in rabbit knee osteoarthritis models[J];Academic Journal of Second Military Medical University;2009-03
2 XIA Yuan-chun,ZENG Ming-kui Master in 2005 Grades of Hunan University of Traditional Chinese Medicine,Changsha,410007;Experimental Study Progress in the Influences of Chinese Herbs on Cell Factors of Uveitis[J];Guiding Journal of Traditional Chinese Medicine and Pharmacy;2008-05
3 GAO Xiu-fen①, WU Yu-sheng. ①Department of Nursing of the General Hospital of Jinan Military Region, Jinan 250031, China;Effects of Xingnaojing injection on the levels of tumor necrosis factor and intercellular adhesion mdecule-1 in rats with acute brain ischemia[J];Practical Journal of Medicine & Pharmacy;2008-07
4 WU Yu-sheng1,ZHANG Wen-gao2,ZHENG Guo-ling1,ZHANG Jian1(1.Department of Internal Medicine,Western Hospital of Shandong University,Jinan 250012,Shandong,China;2.Medical Teaching Research Center,Shandong University of Traditional Chinese Medicine,Jinan 250014,Shandong,China);Effect of Xingnaojing injection on inflammatory reaction and brain edema and preparations in rats with acute brain ischemia[J];Journal of Shandong University(Health Sciences);2007-07
5 MA Fu-ying~(1*),ZHI Guang~1,ZHANG Jian-hong~2,FAN Hao-jun~2 (1.General Hospital of Chinese People′s Liberation Army,Beijing 100853,China;2.General Hospital of Chinese People′s Armed Police Forces,Beijing 100039,China);Experimental Study on Effect of Gardenia Jasminoides Ellis and Other Traditional Chinese Herbs on Viral Myo-carditis in Mice[J];Journal of Applied Clinical Pediatrics;2006-05
6 ZHU Jiang,XIE Wen-li,JIN Yu-zhang,DONG Li-Jin,JIN Xin(Department of Pharmacology,Medical College of Chinese People′s Armed Police Force,Tianjin 300162,China);Effect of gardenia jasminoides ellis on proliferation and secretion of IL-1β in synoviocytes of rheumatoid arthritis rats[J];Acta Academiae Medicinae CPAPF;2007-03
7 YU Wen-jing,LIN Yan,DU Peng-wei,et al.(School of Basic Medicine,Luzhou Medical University,Luzhou 646000,China);STUDY ON THE INJURY MECHANISM OF XINGNAOJING INJECTION(XNJ)ON ENDTOXIN SHOCK IN RABBIT’S KIDNEY[J];Modern Preventive Medicine;2011-24
8 LONG Yuan,WEN Ji-hong,ZHANG Rui-li(Yunnan Institute of Traditional Chinese Medicine and Materia Medica,Kunming,Yunnan,650223);Prevention and Treatment of Rheumatoid Arthritis by Traditional Chinese Medicine[J];Yunnan Journal of Traditional Chinese Medicine and Materia Medica;2011-01
9 HU Chang-ling1,2,LIN Bing1,ZHENG Cheng-jian1,QIN Lu-ping1,2,HAN Ting1 1.Department of Pharmacognosy,School of Pharmacy,Second Military Medical University,Shanghai 200433,China 2.School of Pharmacy,Fujian University of Traditional Chinese Medicine,Fuzhou 350108,China;Advances in studies on natural medicines and their action mechanism for treatment of rheumatoid arthritis[J];Chinese Traditional and Herbal Drugs;2011-07
10 JIN Xin,SUN Jing,XIE Wenli,WAN Zongming,JIN Yuzhang,ZHU Jiang(Department of Pharmacology,Medical college of Chinese People′s Armed Police Forces,Tianjin 300162,China);Study of geniposide-acid on anti-inflammatory action for adjuvant-induced arthritis rats and mechanism of synoviocyte apoptosis in vitro[J];China Journal of Chinese Materia Medica;2009-23
【Citations】
Chinese Journal Full-text Database 2 Hits
1 Department of Pharmacology, Medical College of CPAPF (Tianjin 300162) Zhu Jiang and Cai Dehai Tianjin Institute for Drug Control Rui Jing;Antiinflammatory and Analgesic Effects of Cape Jasmine (Gardenia jasminoides)[J];CHINESE TRADITIONAL AND HERBAL DRUGS;2000-03
2 Lin Hong, et al (Institute of Medicinal Plant Development Chinese Academy of Medical Sciences, Beijing));Rheumatoid Arthritis Model in Rat Induced by Type Ⅱ Collagen and Freund's Complete Adjuvant[J];ACTA LABORATORIUM ANIMALIS SCIENTIA SINICA;1999-01
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 SHAN Bao-en,LI Jun-xin,ZHANG Jing,LIANG Wen-jie,LI Hong-fen(Science and Research Center,The Fourth Hospital of Hebei Medical University,Hebei Shijiazhuang050011,China);The Anti-tumor in Vitro Effect of Cortex Periplocae and Its Analogues Extracted[J];Carcinogenesis,Teratogenesis and Mutagenesis;2005-05
2 LI Jun-xin1,JIANG Yu-hong1,SHAN Bao-en2(1.Women and Children's Medical Center,Qingdao 266011,Shandong;2.Science and Research Center,The Fourth Hospital of Hebei Medical University,Shijiazhuang 050011,Hebei,China);The immunoregulatory activity of cortex periplocae extract on the mice lymphocyts[J];Carcinogenesis,Teratogenesis & Mutagenesis;2010-04
3 LI Yun-xian et al (Department of Basic Courses,Southwestern Forestry College,Kunming,Yunnan 650224);Determination on Trace Elements in Gardenia by Microwave Digestion-ICP-AES[J];Journal of Anhui Agricultural Sciences;2010-22
4 CHEN Bi Yun,LI Da Ren (Dermatology Hospital of Guangdong,Jiangmen 529030 );The clinical observation of treating verruca plana by combining transfer factor with xiaoyoutang[J];Anhui Medical and Pharmaceutical Journal;2004-03
5 MA Yan1,WANG Yong-zhong1,GAO Jia-rong1,ZHAO Wei-zhong2(1.Division of Pharmac,First Affiliated Hospital of Anhui College of Traditional Chinese Medicine,Hefei,Anhui 230031;2.Dept of Pharmacology,Anhui Medical University,Hefei,Anhui 230032);Protective effect of total glycosides of Zhizi on gastric mucosal lesion induced by low dose aspirin[J];Anhui Medical and Pharmaceutical Journal;2008-12
6 CHEN Zhe,ZHAI Xiao feng,LING Chang quan (Changhai Hospital,Second Military Medical University of PLA,Shanghai 200433,China);CLINICAL OBSERVATION OF SYNERGIC AND ANTI-TOXIC EFFECTOF SHENGMAI INJECTION ON PRIMARY LIVER CANCER WITH TREATMENT OF TRANSCATHETER ARTERIAL EMBOLIZATION[J];JOURNAL OF ANHUI TRADITIONAL CHINESE MEDICAL COLLEGE;2000-05
7 HANG Li,MA Shi-ping,LONG Yin,FANG Kun-quan,WANG Zong-ren (Xijing Hospital,the 4th Military Medical University,PLA,Shaanxi Xi'an 710032,China);EFFECT OF HUOXUE TONGMAI TABLET ON HEMORRHEOLOGY AND HYPERLIPEMIA IN EXPERIMENTAL ANIMALS[J];Journal of Anhui Traditional Chinese Medical College;2000-06
8 XIAO Tie hui, WANG Zong ren, LI Jing hua, MA Shi ping, MA Jing, XIA Tian,LI Jun chang (Xijing Hospital, the 4th Militity Medical University,PLA,Shaanxi Xi′an 710032, China);EFFECT OF QIDAN TONGMAI TABLET ON BLOOD LIPID, HEMORRHEOLOGY AND RED BLOOD CELL MEMBRANE FLUIDITY IN RATS WITH HYPERLIPEMIA[J];Journal of Anhui Traditional Chinese Medical College;2002-01
9 CHEN Hua dong, ZHANG Yu liang,WU Jun,XUE Song (The 421th Hospital, PLA, Guangdong Guangzhou 510310, China);Clinical Observation on the Treatment of Fatty Liver with Liver-soothing and Lipid-reducing Decoction[J];Journal of Anhui Traditional Chinese Medical College;2003-06
10 LIU Guo-sheng,LI Li,CHEN Guang-liang (Department of Integrated Traditional Chinese and Western Medicine, Anhui College of Traditional Chinese Medicine, Anhui Hefei 230038,China);Study on Anti-aging Effect of Bushen Granule[J];Journal of Anhui Traditional Chinese Medical College;2005-01
China Proceedings of conference Full-text Database 5 Hits
1 LIN Qizhan 1,LI Fei 2,FAN Liming 2,HUANG Jing 1,BAO Kun 1,LU Fuhua 1,WU Xiuqing 1 (1.Guangdong Provincial TCM Hospital Hemodialysis Center,Guangzhou 510120,China;2.Guangzhou University of Traditional Chinese Medicine,Guangzhou 510405,China);The Effect of Tongmai Oral Solution on Cardiac Function and Structure in Patients with End-stage Renal Disease during Maintenance Hemodialysis[A];[C];2009
2 MOU Jinjin, ZHOU Jia, ZHANG Ying, WANG Zhuo (Department of Pharmacy, Changhai Hospital, Second Military Medical University, Shanghai 200433);Prevention and treatment of chemotherapy-induced phlebitis by Chinese and Western medicine in the perspective of pharmacological mechanism[A];[C];2010
3 Qizhan LIN~1,Fei LI~2,Liming FAN~2,Jing HUANG~1,KunBAO~1,Fuhua LU~1,Xiuqing WU~1 (1 Guangdong Provincial TCM Hospital Hemodialysis Center,Guangzhou,510120,China;2.Guangzhou University of Traditional Chinese Medicine,Guangzhou,510405,China);The effect of Tongmai Oral Solution on cardiac function and structure in patients with end-stage renal disease during maintenance hemodialysis[A];[C];2009
4 XUE Bao-yun,LI Wen,LI-Li,XIAO Yong-qing (Institute of Chinese Materia Medica,China Academy of Traditional Chinese Medicine,Beijing 100700,China);A Pharmacodynamic Research on Chromone Glucosides of Fangfeng[A];[C];2001
5 LI Wen,YIN Xiao-jie,LIAO Fu-long,FU Gui-lan and HU Shi-lin;Comparisons on Anti-coagulation and Anti-platelet Aggregation Effects of Paeonia Extracts from Six Origins[A];[C];2002
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 CHENG He Li,ZHAO Xin Min 1 (Dept of Pharmacy , the First Affiliated Hospital of Anhui Medical University,Hefei 230022; 1Liansheng Science and Trading Co.Ltd,Hefei 230022);The eperimental research of anti-inflammation effect of jasminoidin[J];Anhui Medical and Pharmaceutical Journal;2004-03
2 LIU Li-chao,HUANG Hong-lin,LAI Zheng-quan,LIAO Hui-jun(Jiangxi College of Traditional Chinese Medicine,Nanchang 330006,China);Determination of water soluble polysaccharide in fructus gardeniae[J];Anhui Medical and Pharmaceutical Journal;2005-11
3 FAN Li,LI lin,HE Hui-feng(Department of Dermatology,Sichuan Provincial People's Hospital,Sichuan Academy of Medical Sciences,Chengdu 610031,China);Pharmacological studies on anti-inflammatory and analgesic effects of radix angelicae pubeascentis's volatile oil[J];Anhui Medical and Pharmaceutical Journal;2009-02
4 XIA Lun-zhu,XU Xian-xiang,ZHANG Rui(The First Affiliated Hospital of Anhui College of Traditional Chinese Medicine,Anhui,Hefei 230031);Effect of total saponins of clematis on adjuvant arthritis in rats[J];Anhui Medical and Pharmaceutical Journal;2009-04
5 Liu Jian (The First Affilated Hospital,Anhui College of TCM,Hefei 230031);LEARNING EXPERIENCE OF PROF.HAN MINGXIANG IN TREATING LIJIE DISEASE[J];JOURNAL OF ANHUI TRADITIONAL CHINESE MEDICAL COLLEGE;1999-05
6 LIU Jian Tutor:Professor HAN Ming xian (The First Affiliated Hospital ,Anhui College of TCM, Anhui Hefei 230031,China);DIFFERENTIATION TREATMENT FOR AGED RHEUMATOID ARTHRITIS[J];Journal of Anhui Traditional Chinese Medical College;2001-06
7 LIU Jian,HAN Ming xiang,ZHANG Wan dong,CHEN Guang liang,LEI Li (The First Hospital Affiliated to Anhui College of Traditional Chinese Medicine,Anhui Hefei 230031,China);INFLUENCE OF XINFENG CAPSULE ON SERUM LEVEL OF IL-1, TNFα,IL-4,AND IL-10 IN ADJUVANT ARTHRITIS RATS[J];Journal of Anhui Traditional Chinese Medical College;2002-02
8 HUANG Qing chun,ZHANG Sheng peng,HUANG Wei yi,XU Qiu ying, CHEN Guang xing,SHEN Ying,MA Wei (Guangzhou General Hospital of Guangzhou Command Area,PLA,Guangdong Guangzhou 510010,China);EFFECT OF COMPOUND DANSHEN INJECTION ON IL-1β SECRETION BY SYNOVIOCYTES IN COLLAGEN-Ⅱ INDUCED ARTHRITIS RATS[J];Journal of Anhui Traditional Chinese Medical College;2002-02
9 HUANG Qing chun,XU Qiu ying, JIE Li gang, HUANG Wei yi,CHEN Guang xing,SHEN Ying (Guangzhou General Hospital of Guangzhou Military Region,PLA,Guangdong Guangzhou 510010,China);EFFECT OF COMPOUND DANSHEN INJECTION ON EXPRESSION OF IL- 1β mRNA BY SYNOVIOCYTES IN CIA RATS[J];Journal of Anhui Traditional Chinese Medical College;2002-05
10 CHEN Ji fan ,HUANG Qing chun ,CHEN Guang xing,YE Liu zhong,LIU Qing ping,LI Xiao juan (Guangzhou University of Traditional Chinese Medicine, Guangdong Guangzhou 510010,China);Effect of Tongbiling on Pathology of Synovial Membrane in CIA Rats[J];Journal of Anhui Traditional Chinese Medical College;2003-02
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 GAO Fei1),WU Dingfeng2),XUE Yidong1),DONG Zhiyan1).1)Department of Neurology,Hospital Affiliated to yan'an University,Yan'an 716000,Shanxi;2) The Second Department of Neurology,Shanxi Provincial Nuclear Industry 215 Hospital;Effects of xingnaojing on free radical and clinical efficacy in acute cerebral infact patients[J];Clinical Medicine;2008-10
2 ;类风湿性关节炎的中医辨证施护[J];Journal of Nurses Training;2012-09
3 ZHOU Hao1,LI Zhi-huan2,SHI De-sheng3 1.Tianjin Medical University General Hospital,Tianjin 300052,China 2.Tianjin Zhongxin Pharmaceutical Group Co.,Ltd.Traditional & Herbal Medicine Company,Tianjin 300079,China 3.Tianjin Danxi Traditional Chinese Medicine Institute,Tianjin 300061,China;Comparison on dissolution between Xitong Dropping Pills and Xitong Capsule[J];Drugs & Clinic;2012-02
4 HU Xue-ling Lanzhou Municipal Hospital of TCM,Lanzhou 730050,China;Clinical Observation on Hot Compress with Herbs and Infrared in Treating Rheumatoid Arthritis[J];Western Journal of Traditional Chinese Medicine;2012-07
5 ZHAO Jun,XING Tao,DONG Lin,WEI GUO-Jun,LEI Ning-Bo,WANG ZHi-yong,XU Yu-de Gansu Province Hospital of Traditional Chinese Medicine,Lanzhou 730050,China;Effects of GuCiXiao Cataplasm on IL-1β and TNF-α of Rabbits with Knee Osteoarthritis[J];Western Journal of Traditional Chinese Medicine;2012-11
6 YU Hou-you,HE Xiang-hui,WANG Yan-jun,Yin Wen(Department of Emergency Medicine,Xijing Hospital,the Fourth Military Medical University,Xi'an 710033,China);Effects of Xingnaojing Injection on Bcl-2 Gene Expression and Delayed Neuronal Damage Following Acute Severe Carbon Monoxide Poisoning in Rats[J];Acta Academiae Medicinae Jiangxi;2009-01
7 YUAN QIN1,KAN Wei-bing1,SONG Peng-fei1,XIE Dian-hong1,JIANG Yu-xiang1,WANG Yong-jun2(1.Department of Orthopedic Injuries of Putuo Hospital,Shanghai University of Traditional Chinese Medicine,Shangshai 200062,China;2.Institute of Spine Disease,Shanghai University of Traditional Chinese Medicine,Shangshai 200032,China);Basic Research for Treatment of Osteoarthritis with Chinese Medicine[J];Journal of Liaoning University of Traditional Chinese Medicine;2012-01
8 QIAO Lijun,WANG Yue,ZHOU Lamei,XIA Weijun,WU Xuesu,SUN Mingxia,MA Guquan,GUO Yunke,YE Lihong Intensive Care Unit,Traditional Chinese Medical Hospital of Nanjing,Nanjing 210001,China;Immune regulatory effects of genistein on animal model of rheumatoid arthritis[J];Immunological Journal;2009-06
9 LING Na1,2,CHEN Ying2(1.Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China;2.Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China);Influence of Fuyanning Decoction on TNF-α in Rats with Chronic Pelvic Inflammation[J];Journal of Liaoning University of Traditional Chinese Medicine;2013-05
10 QIU Xia,XU Yan (Department of Nephrology,the Center Hospital of Karamay,834000 Xinjiang,China);Influence of Methotrexate combined with Leflunomide on ACCP,RF and CRP levels in rheumatoid arthritis patients[J];Journal of Hainan Medical University;2013-04
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Yao Quansheng, Zhou Guolin, Zhu Yanqin, Pan Yuying Hu Junhong, Xue Huizhong Zhang Qin (Nanjing Institute of Materia Medica 210009);Screening Studies on Anti-inflammatory Function of Traditional Chinese Herb Gardenia jasminoides Ellis and Its Possibility in Treating Soft Tissue Injuries in Animals[J];China Journal of Chinese Materia Medica;1991-08
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