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《Chinese Traditional Patent Medicine》 2010-08
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Observation of therapeutic effect of Shensong Yangxin Capsule on bradycardiac arrhythmia

JIN Zhen-yi1, ZHANG Xue-hua1, JIN Hua1, QIN Xiao-zhi1, LI Ning2, PU Jie-lin2 (1. Department of Cardiology,Hospital Affiliated to Yanbian University,Yanji 133000 Jilin,China; 2. Pathology and Physiology Research Center,Fuwai Cardiaovascular Hospital,Chinese Academy of Medical Science,Beijing 100037,China)  
AIM: To observe the curative effect and safety of Shensong Yangxin Capsule (Radix et Rhizoma ginseng,Radix et Rhizoma nardostachyos,etc) on slow arrhythmia of different causes(sick sinus syndrome,slowfast syndrome,atrioventricular block). METHODS: One hundred and thirty-four patients with slow arrhythmias were randomly divided into Shensong Yangxin Capsule treatment group and Xinbao Pills control group. Sixty-nine patients in the treatment group were treated with Shensong Yangxin Capsules,and sixty-five patients in the control group were treated with Xinbao Pills. Both groups had same routine treatment. The period of treatment lasted 4 weeks. Clinical effect and safety of two groups were compared. RESULTS: Improvement rate of symptom of the treatment group(76. 81% ) was significantly higher than that of the control group(41. 54% ),P 0. 05. A total of 73 cases of patients with sick sinus syndrome was included. Heart rate of the treatment group(36 cases) increased 7. 21 beats per minute(bpm),while heart rate of the control group(37 cases) increased 2. 1 bpm. There was significant difference between two groups,P 0. 01. 24 h Holter monitering indicated that total effective rate of the treatment group (69. 45% ) was significantly higher than that of the control group(27. 03% ),P 0. 01. A total of 48 cases of patients with slow-fast syndrome was included. The total effective rate of sinus rhythm improving of the treatment group (73. 08% ) was significantly higher than that of the control group(22. 73% ),P 0. 05. 24 h Holter monitering indicated that obvious effective rate of Shensong Yangxin Capsule on tachycardia of slow-fast syndrome(11. 54% ) was higher than that of the control group(4. 55% ),P 0. 05. The total number of cases of atrioventricular block(AVB) was only 13 cases(6 cases in the treatment group,7 cases in the control group). Three cases of high degree AVB in the treatment group and 1 case in the control group improved to low-grade AVB. There was no significant difference of adverse reactions between the treatment(2. 5% ) and the control group(3. 6% ),P 0. 05 . CONCLUSION: Shensong Yangxin Capsule may be an effective and safe drug for treating bradycardiac arrhythmia.
【Key Words】: Shensong Yangxin Capsule bradycardiac arrhythmia Holter therapeutic effect
【CateGory Index】: R259
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 ZHOU Yu-ping.Department of Cardiology, Guang'anmen Hospital,China Academy of Chinese Medical Sciences, Beijing 100053,China;The effect of Shensongyangxin capsule on clinical symptoms and ECG in patients with paroxysmal atrial fibrillation[J];Chinese Journal of Difficult and Complicated Cases;2007-02
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