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Chemical constituents of sarcocarp of Crescentia cujete

YIN Wei1,2,WU Pei-yun2,LIANG Yi-min2,LIU Jin-song2,WANG Gang2(1.Department of Pharmacology,Xin hua College of Anhui,Hefei 230038,China;2.Department of Pharmacology,Anhui College of Traditional Chinese Medicine & Anhui Key Laboratory of Modernized Chinese Medicine,Hefei 230031,China)  
AIM To study the chemical constituents of sarcocarp of Crescentia cujete.METHODS EtOH(95%,V/V)extracts of sarcocarp of Crescentia cujete were separated and purified by silica gel,RP-18,Sephadex LH-20 column chromatography,respectively.Their structures were elucidated using spectroscopic analysis.RESULTS A total of 18 compounds were isolated and identified as ningpogenin(1),6-O-p-hydroxylbenzoylaucubin(2),3,3′-bisdemethylpinoresinol(3),(22E,24R)-ergosta-7,22-dien-3β-ol(4),ergosta-4,6,8(14),22-dien-3-one(5),cerevisterol(6),5α,8α-epidiory-(22E,24R)-ergosta-6,22-dien-3β-ol(7),β-sitosterol(8),daucosterol(9),3β,5α,9α-trihydroxyergosta-7,22-dien-6-one(10),ergosta-7,22-dien-3-one(11),sesquiterpene(12),4-hydroxybenzonicacid(13),benzoicacid(14),p-hydroxybenzylethanol(15),p-hydroxybenzylalcohol(16),D-allitol(17),5-hydroxymethyl-2-furancarboxaldehyde(18).CONCLUSON All the compounds are isolated from sarcocarp of Crescentia cujete for the first time.
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