Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Traditional Patent Medicine》 2014-03
Add to Favorite Get Latest Update

Determination of prim-O-glucosylcimifugin, 4'-O-β-D-glucosyl-5-O-methylvisamminol,notopterol,isoimperatorin and asarinin in Jiulong Huafeng Pills by HPLC

GAO Sen;LI Zheng-xiang;WANG Zhi-tao;FANG Zhi-zhong;General Hospital,Tianjin Medical University;Department of Pharmacy,College of Pharmacy,Tianjin Medical University,Tianjin Key Laboratary on Technologies Enabling Development of Clinical Therapeutics and Diagnostics ( Theranostics);  
AIM To develop an HPLC method for determining the contents of prim-O-glucosylcimifugin,4'-O-β-D-glucosyl-5-O-meth-ylvisammioside,notopterol,isoimperatorin and asarinin in Jiulong Huafeng Pills( Saposhnikoviae Radix,Notopterygh Rhizoma et Radix,Asari Radix et Rhizoma,Rhei Radix et Rhizoma,Platycodonis Radix,etc.). METHODS An Hypersil C18column was used as the chromatographic column,the flow rate was 0. 9 mL / min. For prim-O-glucosylcimifugin and 4'-O-β-D-glucosyl-5-O-methylvisamminol,the mobile phase A consisted of methanol-acetonitrile( 2 ∶ 1),the mobile phase B consisted of 0. 5% phosphoric acid solution,UV detection wavelength was set at 254 nm. For notopterol and isoimperatorin,the mobile phase A consisted of acetonitrile,the mobile phase B consisted of 0. 1% acetic acid solution,the detection wavelength was set at 310 nm. For asarinin,the mobile phase consisted of acetonitrile-methanol( 85 ∶ 15),the UV detection wavelength was set at 286 nm. RESULTS There was a good linear relationship between the concentration of prim-O-glucosylcimifugin,4'-O-β-D-glucosyl-5-O-methylvisamminol and peak area value when the concentrations of prim-O-glucosylcimifugin and 4'-O-β-D-glucosyl-5-O-meth-ylvisammioside were within the range of 0. 014 6- 0. 292 0 μg( r = 0. 999 1),0. 010 8- 0. 216 0 μg( r = 0. 999 3). The average recoveries were 97. 55%( RSD = 1. 46%) and 97. 73%( RSD = 0. 1. 18%). There was a good linear relationship between the concentration of notopterol,isoimperatorin and peak area value when the concentrations of notopterol and isoimperatorin were within the range of 0. 017 4- 0. 348 0 μg( r = 0. 999 3),0. 012 8- 0. 256 0 μg( r = 0. 999 7). The average recoveries were 97. 62%( RSD = 1. 43%) and 98. 11%( RSD = 1. 39%). There was a good linear relationship between the concentration of asarinin and peak area value when the concentrations of asarinin was within the range of 0. 012 4-0. 248 0 μg( r = 0. 999 2). The average recovery was 97. 65%( RSD = 1. 24%). CONCLUSION The method is accurate,sensitive,reproducible and may be used in the determination of prim-O-glucosylcimifugin,4'-O-β-D-glucosyl-5-O-methylvisamminol,notopterol,isoimperatorin and asarinin in Jiulong Huafeng Pills.
【CateGory Index】: R284.1
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 10 Hits
1 LUO Xiao-Ru,CAO Hong,XING Jun-Bo,WANG Pei-Xian,WU Yan,BAO Rui-Ling(Institute for Drug and Instrument Control,Health Dept,GLD of PLA,Beijing 100071 China)(Guangzhou Anjian Industrial Development Co.Ltd. Guangzhou 510240,Guangdong China)(The Second Artillery General Hospital,Beijing 100088 China);Studies on Quality Control Standard of Dingchu Huafeng Wan[J];Pharmaceutical Journal of Chinese People's Liberation Army;2008-01
2 ZHANG Te-li1,YU Chun-yue2,WEI Xing-bo2,SHAN Jing-si2,LIU Xiao-ying2(1.Department of Pharmacy,the Fifth Affiliated Hospital of Harbin Medical University,Daqing 163316,China;2.School of Pharmacy,Daqing Campus of Harbin Medical University,Daqing 163319,China);Study on the extraction technology of active constituents from saposhnikovia divaricata(Turcz.)[J];Heilongjiang Medicine and Pharmacy;2012-03
3 Li Yun-xia1,ZHENG Xiao-he1,MENG Xian-sheng2(1.Zhejiang Hisun Pharmaceutical Company Limited,Taizhou 318000,China; 2.Chinese Medicine College,Liaoning University of Traditional Chinese Medicine,Dalian 116000,China);Determination of Notopterol Concentrations and Pharmacokinetics in Rat Plasma by High-performance Liquid Chromatography[J];Journal of Nanchang University(Medical Science);2012-07
4 Zhang Wenxue(Chemical Factory Hospital of Shanxi Taiyuan Chemical Industry Group,Taiyuan Shanxi 030021);Study on Chemical Constituents of Notopterygium[J];Journal of Shanxi College of Traditional Chinese Medicine;2008-04
5 YUAN Wen-juan,MENG Qin,LI Ting-ting(Yunnan Institute for Food and Drug Control,Kunming 650011,China);HPLC simultaneous determination of two isoflavonoids,four chromones in Yupingfeng granules[J];Chinese Journal of Pharmaceutical Analysis;2012-02
6 LIU Yu-hong1,YI Jin-hai1,HUANG Jiao2,HUANG Zhi-fang1,LIU Yun-hua1(1.Sichuan Academy of Chinese Medicine Sciences,Chengdu 610041,China;2.Chengdu University of TCM,Chengdu 610072,China);RP-HPLC simultaneous determination of methyleugenol,safrole andasarinin in Asari Radix et Rhizoma[J];Chinese Journal of Pharmaceutical Analysis;2012-05
7 KOU Guifeng1,2, ZHANG Youbo1, YANG Xiuwei1, RONG Rong2(1. State Key Laboratory of Natural and Biomimetic Drugs, Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China; 2.School of Pharmaceutical Sciences, Shandong University of Trational Chinese Medicine, Jinan 250355, China);O-Methylnotopterol,a new natural product from the roots and rhizomes of Notopterygium incisum[J];China Journal of Chinese Materia Medica;2010-09
8 XIE Lin1,HAN Jian-wei 1,FU Cong1,WANG Ya-qin1,XIONG Chang-yuan2(1.Key Laboratory of Traditional Chinese Medicine Resource and Compound Prescription,Hubei University of Traditional Chinese Medicine,Ministry of Education,Wuhan 430061,China;2.Hubei Provincial Hospital of Traditional Chinese Medicine,Wuhan 430061,China);Study on Optimizing Technological Condition of Water Extraction for Shangke Fumigant Decoction by Orthogonal Design[J];Chinese Journal of Experimental Traditional Medical Formulae;2010-13
9 Jiang Li,Shen Guoqing,Cong Chunyan(Chinese Academy of Medical Sciences Dermatological Hospital,Nanjing 210042,China);Determination of Cimicifugoside and 5-O-Methylvismmiside in Compound Fangfeng Capsules by HPLC[J];China Pharmacist;2010-08
10 YANG Fang,WAN Li,XU Si-cong,YE Na(College of Pharmacy,Chengdu University of Traditional Chinese Medicine,State Key Lab of Systematic Research and Utilization of TCM Source,Ministry of Education,Chengdu 610075,China)YANG Rong-ping,WANG Yun-hong(Chongqing Academy of Chinese Materia Medica,Chongqing 400065,China);Content Determination of Imperatorin,Isoimperatorin and Tetrahydropalmatione in Yuanhu Zhitong Capsules by QAMS[J];China Pharmacy;2012-32
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 JIN Pan-pan (Life and Geography Department,Qinghai Normal University,Xi'ning,Qinghai 810008);Research Progress of Notopterygium incisun Ting ex H.T.chang[J];Journal of Anhui Agricultural Sciences;2011-02
2 LIN Yu-shun 1,WU Zeng-an 2,YANG Guo-hua 2,DONG Yong-li 2,LONG Xing-yu 2(1 Beijing NO.6 Hospital,Beijing 100007,China;2 Wangjing Hospital of CACMS,Beijing 100102,China);Observation on the effect of orthopedics postoperative fever by heavy formula of heat-clearing drugs[J];China Journal of Traditional Chinese Medicine and Pharmacy;2013-06
3 CHENG Li-li, XU Yan-yan, Nyirimigabo Eric, LI Yu-bo, ZHANG Yan-jun Tianjin Key Laboratory of Chinese Chemistry and Analysis, College of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;Determination of alkaloids with quantitative analysis of multi-components by single marker[J];Drugs & Clinic;2013-04
4 LI Jian-jun;JIA Guo-lun;WANG Jun;LIANG Jian-qiang;YANG Li;College of Life Sciences,Henan Normal University,Engineering Technology Research Center of Nursing and Utilization of Genuine Chinese Crude Drugs,University of Henan Province;Xinxiang Zuo Jinming Pharmaceutical Co.,LTD;The Rural Science and Technology Research and Development Promotion Center of Fengqiu County;;Morphology and Quality Components Analysis Comparison of Different Lonicera japonica Germplasms[J];Journal of Guangxi Normal University(Natural Science Edition);2013-04
5 SONG Xin;WANG Bing;DING Pu;LI Xian-kuan;CHEN Ting;WU Ya-nan;College of Pharmacy,Liaoning Universtity of Traditional Chinese Medicine;;Effect of 1.8% Compound Sodium Nitrophenolate Stress on Lignans Content of Schisandra chinensis Fruits[J];Northern Horticulture;2014-02
6 HE Meng-ling;HE Fang;XIONG Yang;MA Jia-yu;GONG Wei-jun;YAN Han-jing;Department of Chinese Traditional Medicine,Guangdong Pharmaceutical University;The Second People Hospital of Haizhu District in Guangzhou;;Effect of Methyl Jasmonate on the Content of Patchouli Alcohol From the Leaves of Pogostemoncablin (Blanco) Benth.[J];Northern Horticulture;2014-05
7 DIAO Xinping;YE Yingjian;WANG Lijun;CHEN Meixia;School of Animal Science and Technology,Northeast Agricultural University;;Study on fermentation process of Atractylodes chinensis feed additive[J];Journal of Northeast Agricultural University;2013-12
8 QI Bing;LI Shuang;MENG Xiansheng;BAO Yongrui;WANG Shuai;College of pharmacy,Liaoning University of Traditional Chinese Medicine;;Analysis of Inorganic Elements in Qizhiweitong Particles[J];Guangdong Trace Elements Science;2014-02
9 SHEN Bing-xiang;WANG Tong-sheng;WEI Qing-hong;LI Li;WU Jin-shuang;YU Gui-yuan;WU De-ling;Lu'an Hospital Affiliated to Anhui Medical University;Clinical School of Integrated Traditional Chinese and Western Medicine,Anhui University of Chinese Medicine;Anhui Key Laboratory for Modern Chinese Materia Medica;Anhui Xiehecheng Co.,Ltd.;Department of Science and Technology,Anhui University of Chinese Medicine;;Cardioprotective Effect of Total Flavonoids in Chrysanthemum morifolium Ramat.from Bozhou in Rats with Acute Myocardial Ischemia[J];Journal of Anhui University of Chinese Medicine;2014-01
10 WANG Qiong;LIU Shou-jin;LI Chang-lai;HU Zong-qun;LU Hong-ming;ZHAO Bao-lin;School of Pharmacy,Anhui University of Chinese Medicine;Hexian Hospital of Traditional Chinese Medicine;Hexian People's Hospital;Anhui College of Traditional Chinese Medicine;;Resource Investigation of Common Medicinal Plants in Hexian County of Anhui Province,China[J];Journal of Anhui University of Chinese Medicine;2014-01
China Proceedings of conference Full-text Database 4 Hits
1 Zhou Shu-xiang,Cheng Gang,Zeng Ling (the First People’s of Changde City,Changde,415003 );Pharmaceutical care for a severe bone trauma patient with secondary infection[A];[C];2012
2 GU Jia-qin,ZHU Jun(Department of pharmacy,Shanghai Chest Hospital,Shanghai 200030,China.);Determination of Specnuezhenide and Naringin in Qiyelin Granules by HPLC[A];[C];2012
3 LI Li- Min;REN Bin;GUO Jie-wen;CHEN Jian-mei;LIU Ruo-xuan;Guangzhou Hospital of Traditional Chinese Medicine;The First Affiliated Hospital of Sun Yat-Sen University;;Analysis of Volatile Compositions of Panax Notoginseng(Burk.) F.H.Chen by HS-SPME- GC-MS[A];[C];2014
4 MENG Shu1 LIN Yu-lian2 ( 1.Yancheng Health Vocational Technical College;Yancheng 224005 2. Yancheng Institute for Drug Control of Jiangsu P rovince,,Yancheng 224002);Content Determination and Quality Evaluation of baicalin in Cholagogic Tablet[A];[C];2012
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Yang Xiuwei(School of Pharmaceutical Sciences,Peking University,Beijing 100083);Discovery Strategy for Toxic-invited Constituents and Toxic-effective Substances on Chinese Material Medica Based on Processes of Metabolism and Disposition in Intra-body[J];China Journal of Traditional Chinese Medicine and Pharmacy;2007-02
2 CAI Shaoqhg;WANG He; CHEN Shizhong; LOU Zhicen(Department of Pharmacognosy,Beijing Medical University 100083);STUDIES ON THE NON-VOLATILE CHEMICAL CONSTITUENTS OF ASARUM HETEROTROPOIDES VAR. MANDSHURICUM[J];JOURNAL OF BEIJING MEDICAL UNIVERSITY;1996-03
3 WU Zhen-Gang1,WANG Qing-Wei2,LIU Xue-Ying2,LI Jun-Chang4,QIAN Xiao-Hong2,LU Li-Hua3,WANG Qiao-Feng3,LI Xiao-Ye31Department of Pharmacy,North China Coal Medical College,Tangshan 063000,2Department of Pharmacy,Tangdu hospital,Fourth Military Medical University,Xi'an 710038,3Department of Medicinal Chemistry,School of Pharmacy,4Department of Traditonal Chinese Medicine,Xijing hospital,Fourth Military Medical University,Xi'an 710033,China;Determination of methyleugenol and safrole in essential oil of Asarum by RP-HPLC[J];Journal of the Fourth Military Medical University;2008-13
4 WANG Hai-Bo DI Xue BAO Yong-Rui MENG Xian-Sheng CAO Ai-Min(Liaoning University of T.C.M.,Dalian,Liaoning 116600,P.R.China);Chromatography Fingerprint of Rhizoma et Redix Notopterygii by HPLC-Fluorescence Detection[J];Chinese Journal of Spectroscopy Laboratory;2010-02
5 BAI Yaowu,YANG Junhong,WANG Shuhua.Department of Anesthesiology,Tangshan Maternal and Children Health Hospital,Hebei,Tangshan 063000,China;Detection of pharmacokinetics of remifentanil at late trimester of pregnancy by using Rosenblueth method of non compartment model[J];Hebei Medical Journal;2009-18
6 Zhang Li,Wang Yu(Nanjing Institute for Drug Control,Nanjing 210008,China)Li Zhengyan(Nanjing University of Traditional Chinese Medicine,Nanjing 210046,China);HPLC-ELSD DETERMINATION OF ASTRAGALOSIDE IN YUPINGFENG CAPSULE[J];Chemical Analysis and Meterage;2009-01
7 YANG Xiu-Wei②,GUO Qing-Mei②③,ZHANG Cai-Yu④⑤,ZHANG Ben-Gang⑤(②The State Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences,Peking University,Beijing 100083 China)(③Shandong University of Traditional Chinese Medicine,Jinan 250014,Shangdong China)(④National Institute for the Control of Pharmaceutical and Biological Products,Beijing 100050 China)(⑤Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100094 China);Further Studies on the Chemical Constituents of the Root of Angelica pubescens f.biserrata[J];Pharmaceutical Journal of Chinese People's Liberation Army;2008-05
8 YANG Xiu-wei(State Key Laboratory of Natural & Biomimetic Drugs,School of Pharmaceutical Sciences,Peking University,Beijing 100083,China);Application of NMR for Structural Dedication of Forbesoside[J];Chinese Journal of Magnetic Resonance;2006-04
9 Zhang Wenxue(Chemical Factory Hospital of Shanxi Taiyuan Chemical Industry Group,Taiyuan Shanxi 030021);Study on Chemical Constituents of Notopterygium[J];Journal of Shanxi College of Traditional Chinese Medicine;2008-04
10 SUN Hui 1 JIANG Shunyuan 2 ZHOU Yi 2 FANG Junmin 3 (1.Department of Environment Science and Engineering,Sichuan University,Chengdu 610065; 2.Sichuan Institute of Chinese Meteria Medica,Chengdu 610065; 3.Chengdu Library of the Chinese Academy of Sciences,Chengdu 610041);Present Situation and Ethno botany Survey of Chinese and Tibetan Traditional Medicinal Plants of Notopterygium[J];World Sci-tech R & D;2004-06
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved