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Studies on the Chemical Constituents of Fuling(Poria cocos)

Wang Liya;Wan Huijie (Hubei Research Institute of Chemistry,Wuhan 430074)Address: Wang Liya,Hubei Institute of Chemisty Research,Wuhan  
Eight compounds were isolated from Poria cocos (Schw. )Wolf by solvent extraction. 4 of them (Ⅰ ~ Ⅳ )were obtained from ethereal extract,while the other 4 (Ⅴ ~Ⅷ )from ethanol extract. On the basis of physico-chemical properties and spectral analysis (IR,UV,EI、FD MS and NMR),they were identified as 35-hydroxy-16α-acetoxy-lanosta-7, 9 (11 ), 24-trien-21-oic acid (Ⅰ ),O-acetylpachymic acid (Ⅱ ), 3β-hydroxy-lanosta-7, 9 (11), 24-trien-21-oic acid (Ⅲ), β-amyrin acetate (Ⅳ ), O-acetylpachymic acid-25-ol (Ⅴ), methylO-acetylpachymate (Ⅵ ), methyl pachymate (Ⅶ ),and ganoderic acid (Ⅷ). Ⅳ and Ⅷ were isolated from P. cocos (Schw. )Wolf for the first time. Ⅵ and Ⅶ were isolated from natural sources for the first time. Ⅰ and Ⅴ were two newly discovered compounds. The 13CNMR spectral data of Ⅰ, Ⅱ, Ⅲ, Ⅴ,Ⅵ and Ⅶ were presented for the first time in this paper.
【Fund】: 湖北省自然科学基金
【CateGory Index】: R284
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