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《CHINESE TRADITIONAL AND HERBAL DRUGS》 2000-03
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Antiinflammatory and Analgesic Effects of Cape Jasmine (Gardenia jasminoides)

Department of Pharmacology, Medical College of CPAPF (Tianjin 300162) Zhu Jiang and Cai Dehai Tianjin Institute for Drug Control Rui Jing  
The antiinflammatory and analgesic effects of a 75% methanolic extract of Gardenia jasminoides Ellis were studied at a high dose (3 0 g/kg) and a low dose (1 0 g/kg) in experimental animals. Results showed that the extract significantly inhibited the increase of dye exudation induced by acetic acid of 44 7% and 25 6%; significantly inhibited carrageenin induced rat paw edema of 33.6% and 25.4% at 6 h; significantly inhibited cotton pellet induced granuloma formation of 54.1% and 33.0%; reduced the number of writhes induced by acetic acid of 26.8% and 18.9% at high and low doses respectively. These results indicated that the 75% methanolic extract obtained from G. Jasminoides have significant antiinflammatory and analgesic effects.
【CateGory Index】: R285
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