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《Chinese Traditional and Herbal Drugs》 2005-11
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Chemical constituents from fruiting bodies of Ganoderma lucidum

ZHANG Xiao-qi 1,2 , YIN Zhi-qi2, YE Wen-cai 1,2 , ZHAO Shou-xun2(1. Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, China; 2. Department of Natural Pharmaceutical Chemistry, China Pharmaceutical University, Nanjing 210038, China)  
Objective To study the chemical constituents from fruiting bodies of Ganoderma lucidum. Methods Various kinds of chromatographic methods were used to separate the chemical constituents from the fruiting bodies of G. lucidum. Their structures were determined by NMR and MS spectral data. Results Seven compounds were isolated from the ethyl acetate extract of the fruiting bodies of G. lucidum and characterized as ergosta-7, 22-dien-3β-yl pentadecanoate (Ⅰ), ergosteryl palmitate (Ⅱ), ergosta-7, 22-dien-3β-ol (Ⅲ), ergosterol (Ⅳ), ganoderic acid C2 (Ⅴ), ganodermanontriol (Ⅵ) and 1, 2-benzenedicarboxylic acid bis (1-methylpropyl) ester (Ⅶ), respectively. Conclusion Compound Ⅰ is a new compound and compound Ⅶ is isolated from G. lucidum for the first time.
【CateGory Index】: R284
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