Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Traditional and Herbal Drugs》 2006-10
Add to Favorite Get Latest Update

Purification technology of anthraquinone aglycone from Cassia obtusifolia seeds by macroporous adsorption resin

ZHANG Xiao-lu~ 1,2 , SONG Yuan-ying~3, MENG Xiang-ying~2, BO Hua-ben~2, WU Yin~ 1,2 , BAO Yong-li~ 1,2 , LI Yu-xin~1 (1. Research Center of Agriculture and Medicine Gene Engineering of Ministry of Education, Changchun 130024, China; 2. Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China; 3. People′s Hospital of Changchun, Changchun 130051, China)  
Objective To study the purification technology of anthraquinone aglycone from Cassiae obtusifolia seeds by macroporous adsorption resin. Methods Taking the content and the extraction rate of anthraquinone aglycone as the main standard index, the efficiency to extract anthraquinone aglycone with ether and chloroform was compared, and the adsorption and desorption characters as well as the purification capacities of six types of macroporous adsorption resins, such as S-8, AB-8, X-5, NKA-12, D4020, and D101, used to treat anthraquinone aglycone were investigated preliminarily. Results Anthraquinone aglycone with the content of 42.62% was got from C. obtusifolia by extracting with chloroform, purified with S-8 type macroporous adsorption resin, eluted to pH7 by water, then concentrating and acidificating the eluent by alcohol-5% NaOH (4∶1). Conclusion A preparation and purification technology of anthraquinone aglycone has been established. It provides the supporting for the industrialized production of anthraquinone aglycone from C. obtusifolia seed.
【Fund】: 国家自然科学基金资助项目(30472169);; 国家中医药管理局资助项目(04-05ZP21);; 吉林省中医药管理局资助项目(2004-114);; 吉林省科技厅重大项目(20020502);; 吉林省科技攻关项目(20030905)
【CateGory Index】: TQ461
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 4 Hits
1 CHEN Xiao - liang;RUAN Jia;XU Chao - qun;YUAN Zhi - xiang;WANG Li - zhen;BIAN Jun - jie;College of Pharmacy,Chengdu University of Traditional Chinese Medicine;Sichuan Academy of Chinese Medicine Sciences;;Study on the purification procedure of Cassiae semen and Angelica dahuricae in Zhigui tablets[J];华西药学杂志;2014-01
2 ZHONG Xu,WANG Li,XU Guangtao,CAO Yue,XU Nan(Liaoning University of Traditional Chinese Medicine,Dalian 116600,Liaoning,China);Study on Purification Technology of Dissociation Anthraquinones in Radix et Rhizoma Rhei with Macroreticular Resin[J];中华中医药学刊;2013-06
3 TAN Zhi-jian,LI Fen-fang,LIU Tai-ping(College of Chemistry and Chemical Engineering,Central South University,Hunan Changsha 410083,China);Study on the separation and purification of anthraquinone aglycone by polyamide resin[J];中国医院药学杂志;2011-11
4 JIN Ru-cheng~1 XIE Wei-xue~2 PANG Yan~3 (1.School of Life Science and Engineering,Lanzhou University of Technology;2.School of Petrochemical Technology,Lanzhou University of Technology,Lanzhou 730050,China;3.School of Chemical Engineering,Shenzhen University,Shenzhen 518060,Guangdong,China);Effects of macroporous resin on the adsorption and purification of total anthraquinones in Radix Et Rhizoma Rhei[J];兰州大学学报(医学版);2008-01
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LIU Qing1, LI Feng1, REN Qin-You2, WANG Xin3, WANG Wen1, WANG Chang-Hai1, DU Yong-Ping11PLA Centre of Traditional Chinese Medicine, Department of Traditional Chinese Medicine, 3PLA Institute of Gastroenterology, Xijing Hospital, Fourth Military Medical University, Xi'an 710033, China, 2Department of Traditional Chinese Medicine, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China;Regulating effect of aquaporin2 expression by chrysophanol on intestinal epithelial cell line LoVo[J];第四军医大学学报;2009-09
2 KE Zhong-cheng~(1),GUI Shuang-ying~2,ZHOU Ya-qiu~2(1.Huangshan University,Huangshan 245041,China;?2.Anhui College of TCM,Hefei 230031,China);Application of Polyamide Resin in Purification of Hyperoside from Hypericum perforatum L.[J];中国实验方剂学杂志;2008-11
3 GUAN Jing,WANG Chun-lan,GUO Shun-xing,XIAO Pei-gen(Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100094,China);Study on Extraction of Total Flavonoids in Anoectochilus roburghii by Orthogonal Design[J];中国药学杂志;2008-21
4 BAO Jun-qiang LI Feng ZHANG Wen-sheng WANG Han-min LIU Qing HAN Hua LIANG Liang DU Yong-ping.Department of Traditional Chinese Medicine,Xijing Hospital,the Fourth Military Medical University,Xi'an 710032,China;Effects of total anthraquinone in rheum on aquaporin 2,4 expression in rat kidney[J];中华肾脏病杂志;2008-08
5 BAO Jun-qiang~1 LI Feng~1 ZHANG Wen-sheng~1 XU Yan-bo~1 LIU Qing~1 Wang Xin~2 ZHAO Yi-ling~3 WANG Chang-hai~1 (1.Department of Traditional Chinese Medicine,Xijing Hospital,Fourth Military Medical University,Xi'an 710032,China; 2.Department of Gastroenterology Xijing Hospital,Fourth Military Medical University,Xi'an 710032,China; 3.Department of Pathology,Fourth Military Medical University,Fourth Military Medical University,Xi'an 710032,China);Effect of total anthraquinone in rheum on aquaporin 2 expression in rat distal colon[J];中国中药杂志;2008-14
6 ZHANG Wen-sheng1,LI Feng1,BAO Jun-qiang1,WANG Sheng-chun1,SHANG Gang-wei2,LI Jun-chang1,WANG Chang-hai1(Fourth Military Medical University1.Xijing Hospital,Xi′an 710032,China;2.Tangdu Hospital,Xi′an 710038,China);Regulative Effects of Aquaporin 4 Expression by Rhein in Rhubarb to Intestinal Epithelial Cell Line LoVo[J];中药材;2008-05
7 CHENG Dongliang,WANG ZhiweiDept.of Thoracic and Cardiovascular Surgery,Renmin Hospital of Wuhan University,Wuhan 430060,China;Progress in Study on Regulator of Aquaporins[J];武汉大学学报(医学版);2008-03
8 CHEN Yong,LIU Wei,GE Bao-ying,LI Lu-jun,HAN Feng-mei(Hubei Province Key Laboratory of Biotechnology of Traditional Chinese Medicine,Hubei University,Wuhan 430062,China);Studies on Separation and Purification of Isoflavones from Chuanshegan by Macroporous Adsorption Resin[J];中国药学杂志;2007-01
9 ZHANG Xiao-lu~ 1,2 , SONG Yuan-ying~3, MENG Xiang-ying~2, BO Hua-ben~2, WU Yin~ 1,2 , BAO Yong-li~ 1,2 , LI Yu-xin~1 (1. Research Center of Agriculture and Medicine Gene Engineering of Ministry of Education, Changchun 130024, China; 2. Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China; 3. People′s Hospital of Changchun, Changchun 130051, China);Purification technology of anthraquinone aglycone from Cassia obtusifolia seeds by macroporous adsorption resin[J];中草药;2006-10
10 Wu Qun-ying,Jiang Bo-quan,Bai Lan-Ii(Environmental Science and Engineering,Nanchang University,Nachang,Jiangxi,330029);Adsorption and Purification of Glycyrrhizic Acid by Resin with Large Holes[J];江西化工;2006-03
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 JIAO Fei;College of Life Science and Technology,Longdong University;;On the Separation and Purification of Total Rhubarb Anthraquinone through Macroporous Resin[J];陇东学院学报;2015-05
2 LI Ping;LUO Jia-li;LI Yuan-feng;ZHENG Yan-chun;ZHANG Dong-ge;YANG Dong-li;ZHANG Rui-hua;Jingfukang Pharmaceutical Group Co., Ltd.in Hebei Province;Engineering Techonology Research Center of New Excipients of Traditional Chinese Medicine in Hebei Province;;Optimization of the extractive factors of the Rhubarb total anthraquinones ingredients in Xin Jianwei chip tablet[J];中国当代医药;2015-23
3 HE Dan;YANG Lin;ZHANG Jing-qing;College of Pharmacy,Chongqing Medical University;Department of Pharmacy,Chongqing Medical and Pharmaceutical College;;Determination of imperatorin and isoimperatorin in Tianma Toutong tablets by UPLC[J];华西药学杂志;2015-04
4 LIU Xian-yong;SUN Ke-ming;LIU Shi-jun;WANG Yan;Armed Police Corps Hospital of Shandong Province;;Study on Refined Purification Process of Active Ingredients from Huangxiang Granules by Composite Resin Method[J];中国药房;2015-13
5 YANG Yingying;ZHANG Guangjing;ZHANG Shuyuan;XU Yajuan;XU Tunhai;LIU Tonghua;Changchun University of Chinese medicine;Jilin Institute of Traditional Chinese Medicine;Beijing University of Chinese Medicine;Beijing University of Chinese medicine of Traditional Chinese Medicine Health Ministry of Education Key Laboratory;;Application of Macroporous Adsorptive Resin in Study of Traditional Chinese Medicine[J];辽宁中医杂志;2014-10
6 HUANG Xin-quan;LEI Wei;DUAN Xiao-hong;CAI Na;WANG Sheng-yan;LI Yu-shan;The National Hospital of Enshi;Hubei Institute for Nationalities;;Study on Extract Technology of Total Flavone in Polygoni Multiflori Caulis[J];中医药导报;2014-08
7 GAO Hong-li1,TAN Yu-zhu2(1.Hubei University for Nationalities,Enshi 445000,China;2.Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China);Optimization of Purification Technology of Total Valepotriates from Extract of Valeriana jatamansi[J];中国实验方剂学杂志;2013-12
8 ZHANG Zi-long 1,WEI Gang1,LIU Dong-hui1,HUANG Yue-chun2,YANG Li-e1,DUAN Yuan-yuan1(1.Guangzhou University of Traditional Chinese Medicine,Guangzhou 510405,China; 2.The First Affiliated Hospital of Guangzhou University of TCM,Guangzhou 510405,China);Analysis on Correlation of HPLC Specific Chromatogram of Rhei Radix Et Rhizoma and its Ethanol Extract[J];中国实验方剂学杂志;2012-21
9 WANG Tao1,2,XIA Qi-le1,CHEN Jian-bin1,LU Sheng-min1(1.Institute of Food Science,Zhejiang Academy of Agricultural Sciences,Hangzhou 310021,China; 2.College of Chemistry and Life Science,Zhejiang Normal University,Jinhua 321000,China);Research Progress on Extraction,Isolation and Bioactivity of Active Ingredients from Aloes[J];食品与发酵科技;2012-04
10 SHAO Jing et al (Department of Pharmacy,Gansu College of Traditional Chinese Medicine,Lanzhou,Gansu 730000);Research Progress on the Extraction and Purification Process of Anthraquinone in Rheum[J];安徽农业科学;2010-11
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved