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《Chinese Traditional and Herbal Drugs》 2010-06
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Chemical constituents in seeds of Indian mangrove Xylocarpus granatum

YANG Xiao-bo1,YANG Sheng-xin1,LI Min-yi2,PAN Jian-yu3,ZHENG Yi-nan1,WU Jun2(1.College of Chinese Materia Medica,Jilin Agricultural University,Changchun 130118,China;2.Key Laboratory of Marine Bio-resources Sustainable Utilization,South China Sea Institute of Oceanology,Chinese Academy of Sciences,Guangzhou 510301,China;3.Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100193,China)  
Objective To investigate the chemical constituents in the seeds of Indian mangrove Xylocarpus granatum.Methods Compounds were isolated and purified by means of silica,ODS gel column chromatographies,and HPLC.Their structures were elucidated by ESI-MS,NMR spectra,and the known compounds were identified by comparison with their reference data.Results Thirteen compounds were obtained including a new one,named indiangranatumin A(1).thers were known compounds and their structures were elucidated as swietemahonolide(2),febrifugin(3),khayasin T(4),febrifugin A(5),gedunin(6),isolariciresinol(7),phaseic acid(8),aromadendrin(9),4-hydroxy cinnamic acid(10),4-hydroxybenzoic acid(11),4-hydroxyphenylacetic acid(12),and xylogranatinin(13).Conclusion Indiangranatumin A(1) is a new compound and compounds 712 are obtained from this plant for the first time.
【Fund】: 海洋“863”高技术研究与发展资助项目(2007AA09Z407);; 国家自然科学基金资助项目(20772135)
【CateGory Index】: R284.1
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