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《Chinese Traditional and Herbal Drugs》 2014-13
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Chemical constituents from Guanxinning Injection

RUAN Ming;KONG Ling-yi;LUO Jian-guang;School of Biochemical and Environmental Engineering,Nanjing Xiaozhuang University;College of China Marteia Medica,China Pharmaceutical University;  
Objective To investigate the chemical constituents from Guanxinning Injection.Methods The chemical constituents were repeatedly isolated by column chromatographic techniques including silica gel,ODS,Sephadex LH-20,and macroporous resin,and were purified by preparation HPLC chromatography and recrystallization,and their structures were identified by physicochemical properties and spectroscopic data.Results Nineteen compounds were isolated and identified as protocatechuic aldehyde(1),vanillin(2),ferulic acid(3),2-furoic acid(4),senkyunolide I(5),caffeic acid(6),salvianolic acid A(7),isosalvianolic acid A(8),salvianolic acid B(9),isosalvianolic acid C(10),rosmarinic acid(11),1,3-dicaffeoylquinic acid(12),senkyunolide H(13),4-hydroxybenzoic acid(14),m-hydroxybenzoic acid(15),o-hydroxybenzoic acid(16),4-hydroxycinnamic acid(17),methyl rosmarinate(18),and salvianolic acid N methyl ester(19).Conclusion Nineteen compounds are isolated from the Guanxinning Injection for the first time,and all HPLC analyses and literature data show that compounds 2,3,5,13—16 are originated from Ligusticum chuanxiong,compounds 7—11,and 18—19 from Salvia miltiorrhiza,and compounds 1,4,6,12,and 17 from L.chuanxiong and S.miltiorrhiza.
【Fund】: 教育部新世纪优秀人才支持计划(NCET-12-0977)
【CateGory Index】: R286.0
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Chinese Journal Full-text Database 8 Hits
1 Yuan Ke1,Jia An2,Zhu Jian-Xin21(College of Food and Pharmacy,Zhejiang Forestry University,Lin'an 311300)2(College of Pharmacy,Henan University of Traditional Chinese Medicine,Zhengzhou 450008);Structural Identification of Phenylpropanoids from Vernonia Chunii[J];Chinese Journal of Analytical Chemistry;2008-01
2 LI Lu-jun1,SONG Jie2,FENG Li-bin1 1.The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,China 2.Beijing Union Second Pharmaceutical Factory,Beijing 102600,China;Chemical constituents in ethyl acetate fraction from roots of Dendropanax proteus[J];Drugs & Clinic;2013-02
3 TENG Rong wei\+1, ZHOU Zhi hong\+2, WANG De zu\+1, YANG Chong ren\+\{1*\} (1.Kunming Institute of Botany, Chinese Academy of Sciences, Kuming 650204, China; 2.Kungming Institute of Medicine of Biologic Valley, Kunming 650108, China);FOUR CAFFEOYLQUINIC ACIDS FROM MORINA NEPALENSISVAR. ALBA HAND.-MAZZ.[J];Chinese Journal of Magnetic Resonance;2002-02
4 LI Wei, CHEN Fa-kui, YIN Xiang-wu, LIU Xiao-qiu(School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University,Shenyang 110016, China);Chemical constituents of Folium Isatidis[J];Journal of Shenyang Pharmaceutical University;2005-01
5 GUO Xu-hui,ZHANG Na,LI Lin-sen State Nationalities Affairs Commission and Department of Educational Key Lab of Minority Traditional Medicine,MINZU University of China,Beijing 100081,China;Cause analysis on adverse reaction of Chinese materia medica injection and countermeasures[J];Drug Evaluation Research;2012-03
6 ZHENG Xiao-ke, LI Qin, FENG Wei-sheng (Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China.);Studies on chemical constituents of phenolic acids in Rabdosia rubescens[J];Chinese Pharmaceutical Journal;2004-05
7 FENG Mei-ling1,WANG Shu-fang2,ZHANG Xing-xian1 1.College of Pharmaceutical Sciences,Zhejiang University of Technology,Hangzhou 310032,China 2.College of Pharmaceutical Sciences,Zhejiang University,Hangzhou 310058,China;Chemical constituents in fruits of Lycium barbarum[J];Chinese Traditional and Herbal Drugs;2013-03
8 CAO Yuan;QU Hui;YAO Yi;LIU Zhi-hui;FANG Zhu-yuan;Department of Pharmacy, Affiliated Hospital of Nanjing University of Chinese Medicine;;Chemical constituents from Bidens bipinnata[J];Chinese Traditional and Herbal Drugs;2013-24
Chinese Journal Full-text Database 10 Hits
1 WU Wen,LI Lei,YIN Ke-xin(Pharmacy Department of Hefei First People's Hospital,Anhui 230061,China);Adverse reaction reports of guanxinning injection[J];Anhui Medical and Pharmaceutical Journal;2012-04
2 WU Chun-lei,ZHANG Zhi-feng,LIU Yuan(Ethnic Pharmaceutical Institute,Southwest University for Nationalities,Chengdu 610041,China);A Systematic Review on Dipsacaceae Species Research Development[J];Journal of Chengdu Medical College;2009-01
3 WANG Ning1,TANG Li-chang1,YANG Xian-hui3,DENG Shi-ming2(1.College of Horticulture and Landscape Architecture,Hainan University,Hainan Haikou 570228,China; 2.Key Laboratory of Tropic Biological Resources,MOE,Hainan University,Hainan Haikou 570228,China; 3.Public Laboratory Center,Hainan University,Hainan Haikou 570228,China);Chemical constituents of Eupatorium catarium as an alien invasive plant[J];Pratacultural Science;2011-10
4 LIU Ke-yue1,LIU Hai-jun1,WU Jia-zhong1,ZHANG Tie-jun2(1.Medical College of Jiujiang University,Jiujiang 332000,China;2.Tianjin Pharmaceutical Institute,Tianjin 300193,China);Studies on Inhibitory Effect of Active Constituents from Tussilago farfara L.on Lung Cancer Cells LA795 Proliferation[J];Journal of Fudan University(Natural Science);2009-01
5 WANG Qian,BU Wei,CHEN Xuan,BAI Xiao-Hong(Department of Pharmacy,Shanxi Medical University,Taiyuan 030001,China);Mechanism and Concentration of Phenylpropionic Acids by Ionic Liquid Dispersive Liquid Phase Microextraction[J];Chemical Journal of Chinese Universities;2012-04
6 KANG Fei,LU Hua-chong (Department of Phytochemistry,Guangdong College of Pharmacy,Guangzhou,Guangdong 510006,China);Separation and analysis of the chemical constituents of Mallotus apelta[J];Journal of Guangdong College of Pharmacy;2007-02
7 FENG Ji-Nan ZHAO Li-Ping HUANG Hai-Ying a YU Rui-Jin b DENG Bin(Department of Chemistry and Life Science,Xiangnan University,Chenzhou,Hunan 423000,P.R.China)a(Education Affair Office,Xiangnan University,Chenzhou,Hunan 423000,P.R.China)b(College of Sciences,Northwest A&F University,Yangling,Shaanxi 712100,P.R.China);Extraction Technique of Flavonoids Compounds from Artemisia anomala S.Moore by Ultrasonic-Assisted Method[J];Chinese Journal of Spectroscopy Laboratory;2012-03
8 WU Guang-tong;ZHANG Xia-hua;MI Li;Department of Pharmacy,Shanghai Armed Police Corps Hospital;;Analysis on adverse drug reactions induced by Chinese materia medica injections during August, 2009—August, 2012 in Shanghai Armed Police Corps Hospital[J];Drugs & Clinic;2013-05
9 SUN Meili;LI Lei;ZHANG Shuyuan;XUE Feng;ZHANG Jing;XU Tunhai;LIU Tonghua;College of Chinese Tradition Medicine,Jilin Agricultural University;Beijing University of Chinese Medicine;College of Management,Beijing University of Chinese Medicine;Health Cultivation laboratory of the Ministry of Education;Beijing Health Cultivation laboratory of Beijing University of Chinese Medicine;;A research on chemical constituents of medicinal plants of the Vernonia[J];Journal of Changchun University of Traditional Chinese Medicine;2014-03
10 ZHENG Xue-hua (Department of Chemistry and Chemical Engineering,Huaihua University,Huaihua,Hunan 410008);Studies on Chemical Components and Pharmacological Activities in Folium Isatidis[J];Journal of Huaihua University;2007-02
China Proceedings of conference Full-text Database 3 Hits
1 HE Lidong1, ZHANG Shujun1, ANDO Masayoshi2 (1.Chemistry and Chemical Engineering Institute, Qiqihar University, Qiqihar 161006, China; 2. Niigata University, Ikarashi 2-8050, Niigata 950-2181, Japan);Chemical constituents isolated from the root of Ixeris chinensis (Thunb.) Nakai[A];[C];2006
2 Bo WANG, Chang Dai, Ping LIU1* Dept of Clinical Pharmacology, General Hospital of PLA, Beijing, 100853, China;Studies on the chemical constituents from Rhodobryum roseum (Hedw) Limpr(Ⅲ)[A];[C];2006
3 WANG Jin-lan,SONG Xin,ZHANG Zhong-wei,TANG Wan-xia,ZHAO Ming and ZHANG Shu-jun (College of Chemistry and Chemical Engineering,Qiqihar University,Qiqihar,161006);Studies on the chemical constituents of Querus mongolica Fisch[A];[C];2010
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 ZHANG Lin-he, TU Chun-yan, YU Wen-tao, Wu Hong-li (College of Life Sciences and Pharmacy, Nanjing University of Technology, Najing 210009, China);Analysis of Nutritive Components and Flavones in Gynura[J];Amino Acids & Biotic Resources;2004-03
2 Yuan Ke~*1, Yu Li~2 ~1(College of Food and Pharmecy, Zhejiang Forestry University, Lin′an 311300) ~2(Pingdingshan College of Industry, Pingdingshan 467000);Development and Application of Reduced Pressure Concentration Device[J];Chinese Journal of Analytical Chemistry;2005-09
3 LUO Yun-xing1,ZHANG Yun-fu2 1 Florida Food and Drug of Dazhou,Dazhou Sichuan China635000;2 Aerospace Hospital of Chengdu City;Exploration on TCM Injection of the Characteristics of Side Effects,Causes and Preventive Measures[J];Gansu Journal of Traditional Chinese Medicine;2010-07
4 LIN Feng,WANG Jin-hui School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shenyang 110016,China;Chemical constituents of physalins from dried calyx of Physalis alkekengi var. franchetii[J];Drugs & Clinic;2011-06
5 LU Qing,QIN Jun,CHEN Tong (Physical and Chemical Research Center,GUT,Guiyang 550003,China);Study on Essential Oil Components in Stem and Leaf of Gynura Bicolor DC[J];Journal of Guizhou University of Technology(Natural Science Edition);2004-02
6 SHAO Ze-yan1,2,ZHAO Na-xia1,XIA Guang-ping1,BAI Xiu-xiu1,2,DONG Hong-ling1,2,HAN Ying-mei1 1.Tianjin Key Laboratory of Molecular Design and Drug Discovery,Tianjin Institute of Pharmaceutical Research,Tianjin 300193,China 2.Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China;Chemical constituents in ethyl acetate fraction from Daphne genkwa[J];Drugs & Clinic;2013-03
7 LIN XIU-YUN~* ZHANG SHU-DE(Institute of Biophysics, Academia Sinica, Beijing);THE CRYSTAL STRUCTURE AND ABSOLUTE CONFIGURATION OF ARTEANOMALACTONE[J];Acta Chimica Sinica;1985-08
8 WANG Qing-Ji , WANG You-Shao, HE Lei, ZHANG Si (Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China);Study on the chemical constituents of Ipomoea Pes-caprae (L.) Sweet (Ⅰ)[J];Chinese Journal of Marine Drugs;2006-03
9 YANG Xiao-Wei②,HUANG Min-Zhu③,ZHAO Wei-Quan,JIN Yong-Sheng,CHEN Hai-Sheng(②Department of Natural Medicinal Chemistry,College of Pharmacy,Second Military Medical University,Shanghai 200433 China)(③117th Hospital of PLA,Hangzhou 310012,Zhejiang China);Studies on Chemical Constituents of Bidens Bipinnata[J];Pharmaceutical Journal of Chinese People's Liberation Army;2009-04
10 XIE Ming\|yong1,YU Yin\|li1,WANG Yuan\|xing1,YI Xing1,WANG Xiao\|ru2Nanchang 330047,China; n, 361005,China);THE STRUCTURE AND CONTENTS OF FLAVONOIDS IN THE LEAVES OF CYCLOCARYA PALIURUS (BATAL.) ILJINSK[J];Journal of Nanchang University(Natural Science);2003-01
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