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《Chinese Traditional and Herbal Drugs》 2015-06
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Studies on non-alkaloid constituents from Ochrosia borbonica

LIU Yan-ping;HUANG Li-gang;LI Ke-kai;LI Xiao-bao;WANG Xiao-cui;WEN Cheng-quan;FU Yan-hui;Key Laboratory of Tropical Medicinal Plant Chemistry, Ministry of Education, Hainan Normal University;College of Chemistry and Chemical Engineering, Hainan Normal University;  
Objective To study the non-alkaloid constituents from the stems and leaves of Ochrosia borbonica. Methods The chemical constituents were separated and purified by silica gel, Sephadex LH-20, ODS column chromatographies, and preparative HPLC. Their structures were determined by physicochemical properties, spectral data, as well as comparison with the data in literature. Results Fifteen compounds were isolated from the petroleum ether fraction of 70% ethanol extract from the stems and leaves of O. borbonica, and identified as lupeol(1), lupine ketone(2), betulinic alcohol(3), betulinic acid(4), ursolic acid(5), 2α,3β-dihydroxy-ursolic acid(6), 11,12-dehydroursolic acid lactone(7), β-amyrin(8), oleanolic lactone(9), alphitolic acid(10), friedelin(11), cholesterol(12), 24R-ethyl-5α-cholestane-3β, 6α-diol(13), stigmast-7-en-3β-ol(14), and β-sitosterol(15). Conclusion All the compounds are isolated from the plants of Ochrosia Juss. for the first time.
【Fund】: 国家自然科学基金项目资助(21302181);; 海南省自然科学基金项目资助(2014027);; 海南省高校科研项目(HNKY2014-41);; 海南师范大学大学生创新创业训练计划项目(3010151030 3010151053)
【CateGory Index】: R284.1
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 LI Zai-liu 1,2,LUO Bing2,CHENG Fan2,LI Feng-lan1,ZOU Kun2*(1.College of Biological Science and Biotechnology,Beijing Forestry University,Beijing 100083,China;2.Natural Product Research and Exploitation Key Laboratory of Hubei Province,Three Gorges University of China,Yichang,Hubei,443002,China);Studies on the Chemical Constituents of the Spermoderm of Xanthoceras sorbifolia Bunge[J];Lishizhen Medicine and Materia Medica Research;2007-06
2 JIAO Wei1,LU Gai-li2,SHAO Hua-wu1,LU Run-hua1,31Chengdu Institute of Biology,Chinese Academy of Sciences,Chengdu 610041,China;2Inner Mongolia Bayanaoer Chinese Hospital,Bayanaoer,015000,China;3Department of Applied Chemistry,College of Sciences,China Agricultural University,Beijing 100094,China;Studies on the Chemical Constituents of Rhodobryum giganteum (schwaegr.) Par.[J];Natural Product Research and Development;2010-02
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1 FU Ju-qin,QU Wei,LIANG Jing-yu(Department of Natural Medicinal Chemistry,China Pharmaceutical University,Nanjing 210009,China);Progress on Sarcandra Plants[J];Strait Pharmaceutical Journal;2011-01
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1 ZHANG Li-feng, GE Rui, PING Yao-dong, LI Qing-shan*(School of Pharmaceutical Science, Shanxi Medical University, Taiyuan 030001);Preparation and Evaluation of Furannodiene Multiple Emulsion in vitro/vivo[A];[C];2009
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