Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《CHINESE JOURANL OF CNDEMIOLOGY》 1998-02
Add to Favorite Get Latest Update

An experimental study on effects of high fluoride and supplied selenium on thyroid in rats

Lu Chuanhua,Guo Xiaowei,Bian Jianchao,et alShandong institute for endemic disease control and research,Jinan 250014  
 The metabolism of urinary fluoride,thyroid tissue structure and thyroid hormones in sixty rats drunk high fluoride water with 30 or 50mg Fper liter and fed with the selenium (Se) 2.0mg per kilogram were observed to study the effects of high fluoride and supplied Se on thyroid.Results indicated that levels of urinary fluoride raised along with the prolongation of months after drinking high F and excretive contents increased at early stage (4 months) after supplying Se.Thyroid follicular epithelial cells were proliferated actively,and at the same time,the levels of serum free thyroid hormones were higher than those of the control group at early stage.But at late stage (8 months) thyroid follicular epithelial cells appeared retrograde degenerative changes and levels of serum FT3,T4 were lower than those of the control group.There were some relationships between Se and thyroid hormones.It suggested that fluoride could excite thyroid gland,making thyroid functions in state of high compensation at early stage,but could inhibit thyroid gland causing hypothyroidism at late stage.The changes of fluoride and thyroid tissues or thyroid functions were in close relationship with months after drinding fluoride water
【CateGory Index】: R322.51,R599.9
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 4 Hits
1 Chen Fuzun, Cheng Xu, Du Yonggui, et al. (The institute of diseases of HeBei Province, Shi jiazhuang 050011);Effects of selenium at different levels on lipid peroxidation, the capatity of anti-oxidation and thyroid in rats with fluorosis[J];Chinese Journal of Control of Endemic Disenaces;2001-04
2 BIAN Jian-chao , XIAN Shu-mei, YE Ping, et al (Shandong Institute for Prevention and Treatment of Endemic Disease,jinan 250014);The experimental study of selenium on the protective effect in organism injury caused by fluoride[J];Chinese Journal of Control of Endemic Disease;2004-05
3 LIU Guo-yan,ZHANG Wei-dong,GU Jin-hui,CHAI Chun-yan(School of Agriculture and Biology,Shanghai Jiaotong University,Shanghai 200240,China);Effects of Fluoride on Morphological Structure and Function of Thyroids in Rats[J];Journal of Shanghai Jiaotong University(Agricultural Science);2008-06
4 Taiyuan Livestock Epidemic and Quarantine Station Zhang Chunyou Animal Technology College of Shanxi Agricultural University Pang Quanhai Zhang Juan;Study on Fluorine Poisonousness Effect on Animal Nonbone System[J];Taiyuan Science and Technology;2002-02
【Co-citations】
Chinese Journal Full-text Database 3 Hits
1 HUANG Zhi jun,LI Ke jun,LUO Xiao fang,et al (HANG Institute of Occupational Diseases,Zhengzhou 450054, China);Studies on effect of excessive fluoride on CT and PTH level and microelement[J];HENAN MEDICAL RESEARCH;2000-03
2 Guo Xiaowei Lu Chuanhua Bian Jianchao (Shandong Institute for Prevention and Treatment of Endemic Disease Jinan 250014);Effects of fluoride and selenium on thyroid tissues and function in rats[J];STUDIES OF TRACE ELEMENTS AND HEALTH;1998-04
3 HUANG Zhijun  ,LI Kejun,HOU Gang SHEN Zhenhe,WANG Cui ,JIANG Kaiyou,LUO Xiaofang .  Henan Institute of Occupational Dis ease,Zhengzhou450052,China;Study on the correlation of the biochemical indexes in flouride workers[J];Chinese Journal of Indusreial Hygiene and Dccupational Diseases;2002-03
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Gao Xibao, Liu Chunsheng, Sun Jianxia, Zhang Ning, Xu Zhi, Li Jie School of public health, Shandong Medical University, Jinan 250012;THE EFFECTS OF SODIUM FLUORIDE ON THE UV ABSORPTION SPECTRUM OF DIFFERENT TYPES OF DNA[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1998-01
2 Liang Yuhua,Wu Shouwei,Zhang Ding,Pan Weilin (Department of Biology,Bengbu Medical College,Anhui);SISTER CHROMATID EXCHANGE AND MICRONUCLEUS FREQUENCY IN FLUOROSIS[J];ACTA ACADEMIAE MEDICINAE BENGBU;1995-06
3 Wei Zhaojun,Wang Zhange,Zhang Zhifang(Key Laboratory of Silkworm Biotechnology,Ministry of Agriculture, Sercultural Research Institute,Chinese Academy of Agricultural Sciences,Zhenjiang,212018);Effect of Fluoride on the AKLP Activity in Midgut and Larval Weight of Silkworm(Bombyx M L.)ang It's Correlation Analysis[J];Bulletin of Sericulture;2001-02
4 Lu Shun-Iin Lang Hong-chun XU Jun-Iiang(Department of Sericulture, Zhejiang Agriculture University ,Hangzhou 310029 ,China);EFFECT OF FLUORIDE POISONINC ON REGULATION OF GLYCOGEN CATABOLISM IN LARVAL MIDGUTS OF SILDWORM,BOMBYX MORI[J];ACTA SERICOLOGICA SINICA;1994-02
5 Qu Liandong and Chu Guijun(Harbin Veterinary Institute of China Agricultural Academy)Teng Guolin,Zhang Weimu and Yang Guijun (Northeast Agricultural University, Harbin 150030,China);STUDIES ON THE DYNAMIC ULTRAMICROPATHOMORPHLOGY OF LIVER AND KIDNEY OF EXPERIMENTAL CHRONIC FLUOROSIS IN DOMESTIC RABBITS[J];JOURNAL OF NORTHEAST AGRICULTURAL UNIVERSITY;1994-04
6 Sun Yang, et al (Luoyang Institute of Endemic Disease Control, Henan);AFFECTS OF BORON,SELENIUM,FUNIN AND VITAMINE C ON THE BIOCHEMICAL CRITERIONS OF FLUOROSIS RATS[J];Endemic Disease Bulletin;1988-04
7 Li Jian-xue, et al (Tongji Medical University, Wuhan 430030);Quantum Mechanical Calculation of Hydrogen Bond Between Fluoride and Tyrosine Phenolic Hydroxyl[J];Endemic Disease Bulletin;1991-01
8 Lin Fa-fu , Aihaiti , Zhao Hong-xin , Lin Jin , Jiang Ji-yong, Maimaiti, and Aiken (Xinjiang Institute for Endemic Disease Control and Research, Urumqi; Endemic Disease Controlling Office of Hetian District; Sanitary and Antiepidemic Station of Yutian County , Xinjiang);High-fluoride and Low-iodine Environment and Subclinical Cretinism in Xinjiang[J];Endemic Disease Bulletin;1991-02
9 Chen Zhan-yin, et al. (Dept. of Neurology of the Affiliated Hospital of Shihezi Medical College, Xinjiang 832008);Determination of Fluoride in Mice Brains with Chronic Fluorosis[J];Endemic Disease Bulletin;1992-03
10 LIU Kaitai; WANG Guoquan;WANG Shizhen;WU Jiyao;XIAO Biyu(Teaching and Research Section of Environmental Health,Xinjiang Medical University, Urumqi, Xinjiang 830054 China);Effects of Fluoride on The Cell Cycle and Apoptosisin Vitro Organ Culture of Long Bone[J];Endemic Diseases Bulletin (China);1999-04
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 LI Xiao-cui,SHEN Hong-mei,LIU Li-xiang,et al(The Center of Endemic Disease Control,Harbin Medical University,Harbin 150081,China);Study on the effect of drinking water fluoride levels on the hazard caused by excessive iodine[J];Chinese Journal of Control of Endemic Diseases;2009-05
2 LI Cheng-cheng,YU Guang-qian Haerbin Medical University,Chinese Center for Disease Control and Prevention,The Center for Endemic Disease Control, The Instituet for Fluorosis control Haerbin 150081,China;The research progress on drinking brick-tea type fluorosis and the antagonism of antioxidant substances in brick tea[J];Chinese Journal of Control of Endemic Diseases;2012-03
3 WANG Jin-ming~1,CHENG Xiao-fang~2,WANG Jun-dong~1(1.College of Animal Science and Technology,Shangxi Agricultural University,Taigu 030804,China;2.College of Arts and Science,Shanxi Agricultural University,Taigu 030801,China);Fluorosis and Application of Genomics Technology in it[J];China Animal Husbandry & Veterinary Medicine;2006-04
4 CHEN Zhi-xiong,QI Gui-nian*,ZOU Yao,LI Jian-hua College of Horticulture,Sichuan Agriculture University,Ya’an 625014,China;Research Advance on Mechanism of Regulating Lipid Metabolism by Active Ingredients of Dark Tea[J];Journal of Tea Science;2013-03
5 ;饮用水氟碘正常区碘氟排泄相关性研究[J];Contemporary Medicine;2013-18
6 LIU Hong-liang,ZHAO Liang.Environment and Health Institute,Tianjin Centers for Disease Control and Prevention,Tianjin 300011,China;Research Progress in the Relationship between Nutrient Intake and Fluorosis[J];Journal of Environment and Health;2009-11
7 LI Shu,KANG Shi-liang(College of Veterinary Medicine,Northeast Agricultural University,Harbin,150030,China);Functions of nitric oxide in the mechanism of chronic fluorosis in dairy goat[J];Heilongjiang Animal Science and Veterinary Medicine;2007-08
8 GAO Ming-tao LI Hong XU Ke-yu WANG Cui-yao (Department of Biochemistry,Liaoning Medical University,Jinzhou 121000 China);Study of the Cytotoxic Effects of Sodium Fluoride on Primary Porcine Thyrocytes[J];Journal of Liaoning Medical University;2007-05
9 HUANG Rui-zhe1,TIAN Jian-gang1,CHONG Yan2,CHEN Qing-xiu3,RUAN jian-ping.1.The Dental School of Xi'an Jiaotong University,Shaanxi Xi'an 710004,China;2.The Dental Hospital of Xi'an Eity.Shanxi Xi'an 71003,China;3.The Second Hospital of Xi'an Jiaotong University,Shanxi Xi'an 710004,China.;Effect of selenium on the adhesion function of streptococcus mutans[J];Journal of Clinical Stomatology;2011-03
10 TONG Zong-xi~1,WANG Yong-cai~1,YANG Feng-lan~1,KANG Shi-liang~2(1.College of Animal Hasbandry and Veterinary Science,Henan Agricultural University,Zhengzhou 450002 China;2.College of Veterinary Science,Northeast Agricultural University,Harbin 150030,China);Study on the Pathogenesis of Anemia in Chicken with Selenium Deficiency[J];Journal of Henan Agricultural University;2006-02
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Xue Yan;PTH and CT levels in serum of patients with end emic skeletal fluorosis[J];Chinese Journal of Endemiology;1990-06
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved