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《China Modern Doctor》 2013-07
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The epidemic study of birth defect by prenatal screening in Lishui from 2005 to 2011

CHEN Ying HUANG Ziyan HUANG Ying LAN Weiwei Department of Clinical Laboratory,Lishui Meternity and Child Health Hospital,Zhejiang Province,Lishui 323000,China  
Objective To study the epidemiological characteristics of pregnant women sieved before delivery checking in Lishui.Methods Collected the data of pregnant women sieved before delivery during 2005-2011 in the way of monitoring them before pregnancy,and then an epidemiological analysis of birth defect risk was made.Results The high risk-rate was 3.72% in 73228 pregnant women screening,the high-risk rate of 21-trisomy was 2.95%,18-trisomy was 0.23% and NTD was 0.53%.There were significant difference in high-risk rate of different counties(cities and districts)(χ2=60.28,P 0.01),and it was the same tendency among the different gestational weeks(χ2=174.72,P 0.01).The trend is that the risk rate increased with age of pregnant women(χ2=115.51,P 0.01) and the highest was in the group over 35 years old.Conclusion It is important to control the birth defect by preventing the high-risk population which is necessary for improving the human quality.
【Fund】: 浙江省丽水市科学技术局丽科[2005]49号
【CateGory Index】: R714.5
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